Artichoke

What the research shows

No concerns

none of the findings here link it to harm

A variety of thistle grown as food.12

What research says

Studies in people

  • Benefit

    Blood pressure3

    In people with high blood pressure, artichoke supplements may lower blood pressure, but this finding is not certain.

  • Benefit

    Cholesterol levels4

    In studies of people, artichoke supplements lowered total cholesterol, LDL and triglycerides, but not HDL.

  • Benefit

    Waist size5

    In people, artichoke supplements slightly shrank waist size, but weight and BMI barely changed.

  • Benefit

    Heart and blood sugar health6

    In adults, artichoke supplements modestly improved cholesterol, blood pressure, blood sugar handling and liver markers.

  • Benefit

    Blood sugar levels7

    In people, taking artichoke supplements lowered fasting blood sugar, but other blood sugar measures stayed about the same.

  • Benefit

    Blood sugar and insulin8

    In people with a certain gene type, artichoke leaf extract lowered insulin and insulin resistance.

  • Benefit

    Blood vessel health9

    In people with high cholesterol, drinking artichoke juice daily improved blood vessel function and lowered cholesterol.

  • Benefit

    Antioxidant blood markers10

    In people with metabolic syndrome, artichoke leaf extract lowered one blood marker, oxidized-LDL, but not other antioxidant markers.

Animal and lab studies only

  • Open question

    Gut absorption of plant material12

    In lab studies, artichoke miRNAs were not taken up by human intestinal cells after cooking and digestion.

  • Benefit

    Gut bacteria13

    In lab studies, artichoke extract helped good gut bacteria grow, though less than the standard prebiotic.

Study type not stated

  • Benefit

    Liver and heart health11

    Artichoke may help the liver, heart and digestion, but scientists do not yet know how it works in people.

How it’s made and used

The signal at the top counts the findings in people and in animal and lab studies. A concern in studies of people outranks animal and lab studies, and “No concerns” needs at least one finding in people. When most findings in people point one way, the page leans that way (“Mostly”), and every finding is still shown. Findings whose study type is not stated are shown but not counted. This page is a reference, not medical advice. It describes what regulators and published research say. Talk to a doctor or dietitian about your own diet.

Products

The 6 most-scanned of 806 products on Open Food Facts that list artichoke.

  • Fonds d'artichauts Marque Repère · 210 g 1 additive
  • Verdure Sourdough Grilled Vegetables, Taggiasca Olives & Basil Sauce Pizza Croats & Mollica · 1, 471 0 additives
  • ARTICHOKE HEARTS QUARTERS & HALVES MARINATED IN OIL KIRKLAND Signature · 33 oz (0.94 kg) 1 additive
  • Carciofini Rustici in Olio Di Semi di Girasole Italiamo · 340 g e (195 g égoutté) 2 additives
  • Artichaut gorgonzola noisette 420 g 3 additives
  • Carciofini sottolio grigliati Polli · 185 g 1 additive

References

  1. 1artichoke: ingredient taxonomy entry. Open Food Facts.
  2. 2Artichoke. Wikipedia. Accessed September 29, 2026. CC BY-SA 4.0.
  3. 3Moradi M, Sohrabi G, Golbidi M, et al. Effects of artichoke on blood pressure: A systematic review and meta-analysis. Complement Ther Med. 2021;57:102668. doi:10.1016/j.ctim.2021.102668
  4. 4Shahinfar H, Bazshahi E, Amini MR, et al. Effects of artichoke leaf extract supplementation or artichoke juice consumption on lipid profile: A systematic review and dose-response meta-analysis of randomized controlled trials. Phytother Res. 2021;35(12):6607-6623. doi:10.1002/ptr.7247
  5. 5Hemati N, Venkatakrishnan K, Yarmohammadi S, et al. The effects of supplementation with Cynara scolymus L. on anthropometric indices: А systematic review and dose-response meta-analysis of clinical trials. Complement Ther Med. 2021;56:102612. doi:10.1016/j.ctim.2020.102612
  6. 6Jafari A, Karimi MA, Mahmoudinezhad M, Razavi F, Mardani H, Musazadeh V. Artichoke and cardiometabolic health: A systematic and meta-analytic synthesis of current evidence. Diabetes Metab Syndr. 2025;19(10):103328. doi:10.1016/j.dsx.2025.103328
  7. 7Jalili C, Moradi S, Babaei A, et al. Effects of Cynara scolymus L. on glycemic indices:A systematic review and meta-analysis of randomized clinical trials. Complement Ther Med. 2020;52:102496. doi:10.1016/j.ctim.2020.102496
  8. 8Ebrahimi-Mameghani M, Asghari-Jafarabadi M, Rezazadeh K. TCF7L2-rs7903146 polymorphism modulates the effect of artichoke leaf extract supplementation on insulin resistance in metabolic syndrome: a randomized, double-blind, placebo-controlled trial. J Integr Med. 2018;16(5):329-334. doi:10.1016/j.joim.2018.05.006
  9. 9Lupattelli G, Marchesi S, Lombardini R, et al. Artichoke juice improves endothelial function in hyperlipemia. Life Sci. 2004;76(7):775-82. doi:10.1016/j.lfs.2004.07.018
  10. 10Rezazadeh K, Aliashrafi S, Asghari-Jafarabadi M, Ebrahimi-Mameghani M. Antioxidant response to artichoke leaf extract supplementation in metabolic syndrome: A double-blind placebo-controlled randomized clinical trial. Clin Nutr. 2018;37(3):790-796. doi:10.1016/j.clnu.2017.03.017
  11. 11Olas B. An Overview of the Versatility of the Parts of the Globe Artichoke (Cynara scolymus L.), Its By-Products and Dietary Supplements. Nutrients. 2024;16(5). doi:10.3390/nu16050599
  12. 12Cavallini A, Minervini F, Garbetta A, et al. High degradation and no bioavailability of artichoke miRNAs assessed using an in vitro digestion/Caco-2 cell model. Nutr Res. 2018;60:68-76. doi:10.1016/j.nutres.2018.08.007
  13. 13Van den Abbeele P, Ghyselinck J, Marzorati M, et al. In Vitro Evaluation of Prebiotic Properties of a Commercial Artichoke Inflorescence Extract Revealed Bifidogenic Effects. Nutrients. 2020;12(6). doi:10.3390/nu12061552
  14. 14D'Antuono I, Garbetta A, Linsalata V, Minervini F, Cardinali A. Polyphenols from artichoke heads (Cynara cardunculus (L.) subsp. scolymus Hayek): in vitro bio-accessibility, intestinal uptake and bioavailability. Food Funct. 2015;6(4):1268-77. doi:10.1039/c5fo00137d