Artichoke
What the research shows
No concerns
none of the findings here link it to harm
What research says
Studies in people
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Benefit
Blood pressure3
In people with high blood pressure, artichoke supplements may lower blood pressure, but this finding is not certain.
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Benefit
Cholesterol levels4
In studies of people, artichoke supplements lowered total cholesterol, LDL and triglycerides, but not HDL.
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Benefit
Waist size5
In people, artichoke supplements slightly shrank waist size, but weight and BMI barely changed.
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Benefit
Heart and blood sugar health6
In adults, artichoke supplements modestly improved cholesterol, blood pressure, blood sugar handling and liver markers.
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Benefit
Blood sugar levels7
In people, taking artichoke supplements lowered fasting blood sugar, but other blood sugar measures stayed about the same.
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Benefit
Blood sugar and insulin8
In people with a certain gene type, artichoke leaf extract lowered insulin and insulin resistance.
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Benefit
Blood vessel health9
In people with high cholesterol, drinking artichoke juice daily improved blood vessel function and lowered cholesterol.
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Benefit
Antioxidant blood markers10
In people with metabolic syndrome, artichoke leaf extract lowered one blood marker, oxidized-LDL, but not other antioxidant markers.
Animal and lab studies only
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Open question
Gut absorption of plant material12
In lab studies, artichoke miRNAs were not taken up by human intestinal cells after cooking and digestion.
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Benefit
Gut bacteria13
In lab studies, artichoke extract helped good gut bacteria grow, though less than the standard prebiotic.
Study type not stated
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Benefit
Liver and heart health11
Artichoke may help the liver, heart and digestion, but scientists do not yet know how it works in people.
How it’s made and used
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How much the body absorbs14
In lab studies, only a tiny fraction of artichoke polyphenols passed through intestinal cells.
The signal at the top counts the findings in people and in animal and lab studies. A concern in studies of people outranks animal and lab studies, and “No concerns” needs at least one finding in people. When most findings in people point one way, the page leans that way (“Mostly”), and every finding is still shown. Findings whose study type is not stated are shown but not counted. This page is a reference, not medical advice. It describes what regulators and published research say. Talk to a doctor or dietitian about your own diet.
Products
The 6 most-scanned of 806 products on Open Food Facts that list artichoke.
- Fonds d'artichauts Marque Repère · 210 g 1 additive
- Verdure Sourdough Grilled Vegetables, Taggiasca Olives & Basil Sauce Pizza Croats & Mollica · 1, 471 0 additives
- ARTICHOKE HEARTS QUARTERS & HALVES MARINATED IN OIL KIRKLAND Signature · 33 oz (0.94 kg) 1 additive
- Carciofini Rustici in Olio Di Semi di Girasole Italiamo · 340 g e (195 g égoutté) 2 additives
- Artichaut gorgonzola noisette 420 g 3 additives
- Carciofini sottolio grigliati Polli · 185 g 1 additive
References
- 1artichoke: ingredient taxonomy entry. Open Food Facts.
- 2Artichoke. Wikipedia. Accessed September 29, 2026. CC BY-SA 4.0.
- 3Moradi M, Sohrabi G, Golbidi M, et al. Effects of artichoke on blood pressure: A systematic review and meta-analysis. Complement Ther Med. 2021;57:102668. doi:10.1016/j.ctim.2021.102668
- 4Shahinfar H, Bazshahi E, Amini MR, et al. Effects of artichoke leaf extract supplementation or artichoke juice consumption on lipid profile: A systematic review and dose-response meta-analysis of randomized controlled trials. Phytother Res. 2021;35(12):6607-6623. doi:10.1002/ptr.7247
- 5Hemati N, Venkatakrishnan K, Yarmohammadi S, et al. The effects of supplementation with Cynara scolymus L. on anthropometric indices: А systematic review and dose-response meta-analysis of clinical trials. Complement Ther Med. 2021;56:102612. doi:10.1016/j.ctim.2020.102612
- 6Jafari A, Karimi MA, Mahmoudinezhad M, Razavi F, Mardani H, Musazadeh V. Artichoke and cardiometabolic health: A systematic and meta-analytic synthesis of current evidence. Diabetes Metab Syndr. 2025;19(10):103328. doi:10.1016/j.dsx.2025.103328
- 7Jalili C, Moradi S, Babaei A, et al. Effects of Cynara scolymus L. on glycemic indices:A systematic review and meta-analysis of randomized clinical trials. Complement Ther Med. 2020;52:102496. doi:10.1016/j.ctim.2020.102496
- 8Ebrahimi-Mameghani M, Asghari-Jafarabadi M, Rezazadeh K. TCF7L2-rs7903146 polymorphism modulates the effect of artichoke leaf extract supplementation on insulin resistance in metabolic syndrome: a randomized, double-blind, placebo-controlled trial. J Integr Med. 2018;16(5):329-334. doi:10.1016/j.joim.2018.05.006
- 9Lupattelli G, Marchesi S, Lombardini R, et al. Artichoke juice improves endothelial function in hyperlipemia. Life Sci. 2004;76(7):775-82. doi:10.1016/j.lfs.2004.07.018
- 10Rezazadeh K, Aliashrafi S, Asghari-Jafarabadi M, Ebrahimi-Mameghani M. Antioxidant response to artichoke leaf extract supplementation in metabolic syndrome: A double-blind placebo-controlled randomized clinical trial. Clin Nutr. 2018;37(3):790-796. doi:10.1016/j.clnu.2017.03.017
- 11Olas B. An Overview of the Versatility of the Parts of the Globe Artichoke (Cynara scolymus L.), Its By-Products and Dietary Supplements. Nutrients. 2024;16(5). doi:10.3390/nu16050599
- 12Cavallini A, Minervini F, Garbetta A, et al. High degradation and no bioavailability of artichoke miRNAs assessed using an in vitro digestion/Caco-2 cell model. Nutr Res. 2018;60:68-76. doi:10.1016/j.nutres.2018.08.007
- 13Van den Abbeele P, Ghyselinck J, Marzorati M, et al. In Vitro Evaluation of Prebiotic Properties of a Commercial Artichoke Inflorescence Extract Revealed Bifidogenic Effects. Nutrients. 2020;12(6). doi:10.3390/nu12061552
- 14D'Antuono I, Garbetta A, Linsalata V, Minervini F, Cardinali A. Polyphenols from artichoke heads (Cynara cardunculus (L.) subsp. scolymus Hayek): in vitro bio-accessibility, intestinal uptake and bioavailability. Food Funct. 2015;6(4):1268-77. doi:10.1039/c5fo00137d