E161j
Astaxanthin
What the research shows
No concerns
none of the findings here link it to harm
A red colouring found in algae.
It gives salmon and other seafood their red-orange colour.1
- Vegan
- Vegetarian
What research says
Studies in people
-
Open question
Inflammation after hard exercise2
In firefighters, astaxanthin seemed to calm some inflammation after hard workouts, but most differences were within groups.
-
Benefit
PCOS symptoms and inflammation3
In women with PCOS, astaxanthin lowered some inflammation markers, but did not improve weight, hair growth, hair loss or periods.
-
Benefit
Heart failure symptoms4
In people with heart failure, astaxanthin supplements improved breathlessness and tiredness over eight weeks, but studies are still limited.
-
Benefit
Eye-hand coordination5
In people, a supplement with astaxanthin, lutein and zeaxanthin helped eye-hand coordination after screen work.
-
Benefit
Sun-damaged skin6
People taking astaxanthin for 9 weeks showed less sun-related skin moisture loss and better rough skin scores.
-
Open question
Oxidative stress in overweight adults7
In overweight adults, astaxanthin supplements for 3 weeks changed blood markers of oxidative stress.
-
Open question
Fat breakdown in the body9
In healthy men, three months of astaxanthin capsules may have reduced the breakdown of fats.
-
Open question
Egg quality in IVF10
In women with PCOS, astaxanthin led to more mature eggs, but scientists do not yet know whether it lowers OHSS risk.
-
Benefit
Blood sugar and cholesterol11
In obese men, astaxanthin plus CrossFit improved insulin, glucose and lipid levels over 12 weeks.
Animal and lab studies only
-
Benefit
Heart and eye health16
Astaxanthin is said to help prevent heart disease and cataracts, but most research so far is in lab studies.
-
Benefit
Gum and jawbone health in diabetes17
In diabetic mice, astaxanthin reduced gum and jawbone damage, but did not lower blood sugar.
-
Open question
Exercise recovery evidence18
In animal and lab studies astaxanthin improved exercise recovery, but studies in people have given mixed results.
-
Benefit
Fatty liver after menopause20
In mice without ovaries, astaxanthin lessened liver fat, inflammation and scarring.
-
Open question
Clogged arteries22
In lab studies, astaxanthin stopped foam cells forming and calmed inflammation, but the authors did not say if it helps people.
Study type not stated
-
Open question
Long-term eating effects12
Natural astaxanthin cut oxidative and free-radical stress more than synthetic astaxanthin, but long-term eating risks are not well studied.
-
Open question
Long-term health effects13
Scientists do not yet know whether eating synthetic astaxanthin over many years affects human health.
-
Benefit
Antioxidant health effects14
Astaxanthin from microalgae is used as a colour in food and feed, and may have health benefits.
-
Open question
Heart and blood vessels15
Astaxanthin may help prevent hardened arteries, but scientists do not yet know whether it truly works in people.
How it’s made and used
-
Exercise performance in cyclists8
In trained cyclists, taking astaxanthin for four weeks did not improve fat burning or time trial performance.
-
Gut bacteria and tryptophan19
In lab studies, astaxanthin changed gut bacteria and raised the breakdown products of tryptophan.
-
How much the body absorbs21
In lab studies, cooking wild salmon lowered astaxanthin bioaccessibility, and uncooked wild salmon gave more than uncooked farmed salmon.
The signal at the top counts the findings in people and in animal and lab studies. A concern in studies of people outranks animal and lab studies, and “No concerns” needs at least one finding in people. When most findings in people point one way, the page leans that way (“Mostly”), and every finding is still shown. Findings whose study type is not stated are shown but not counted. This page is a reference, not medical advice. It describes what regulators and published research say. Talk to a doctor or dietitian about your own diet.
Regulatory status
Checked Sep 2026-
United States Permitted FDA 21 CFR 73.35
Status reflects the named register on the date checked. It is not a safety rating. A country appears here once we've found this ingredient on its official list.
How we checkProducts
The 3 most-scanned of 39 products on Open Food Facts that list astaxanthin.
- Cold Smoked Atlantic Salmon Specially Selected · 3 oz 2 additives
- Farm-Raised Atlantic Salmon Fillets 365 Whole Foods Market · 32 oz 1 additive
- Smoked nova salmon Acme · 8 oz 1 additive
References
- 1Astaxanthin. Wikipedia. Accessed September 26, 2026. CC BY-SA 4.0.
- 2Gonzalez DE, Dickerson BL, Johnson SE, et al. Impact of astaxanthin supplementation on markers of cardiometabolic health and tactical performance among firefighters. J Int Soc Sports Nutr. 2024;21(1):2427751. doi:10.1080/15502783.2024.2427751
- 3Jabarpour M, Amidi F, Aleyasin A, Nashtaei MS, Marghmaleki MS. Randomized clinical trial of astaxanthin supplement on serum inflammatory markers and ER stress-apoptosis gene expression in PBMCs of women with PCOS. J Cell Mol Med. 2024;28(14):e18464. doi:10.1111/jcmm.18464
- 4Mohammadi SG, Shafie D, Feizi A, Bagherniya M, Ahmadi AR, Kafeshani M. Impact of astaxanthin on oxidative markers, uric acid, and clinical symptoms in heart failure: a randomized clinical trial. BMC Cardiovasc Disord. 2025;25(1):779. doi:10.1186/s12872-025-05260-z
- 5Yoshida K, Sakai O, Honda T, et al. Effects of Astaxanthin, Lutein, and Zeaxanthin on Eye-Hand Coordination and Smooth-Pursuit Eye Movement after Visual Display Terminal Operation in Healthy Subjects: A Randomized, Double-Blind Placebo-Controlled Intergroup Trial. Nutrients. 2023;15(6). doi:10.3390/nu15061459
- 6Ito N, Seki S, Ueda F. The Protective Role of Astaxanthin for UV-Induced Skin Deterioration in Healthy People-A Randomized, Double-Blind, Placebo-Controlled Trial. Nutrients. 2018;10(7). doi:10.3390/nu10070817
- 7Choi HD, Kim JH, Chang MJ, Kyu-Youn Y, Shin WG. Effects of astaxanthin on oxidative stress in overweight and obese adults. Phytother Res. 2011;25(12):1813-8. doi:10.1002/ptr.3494
- 8Res PT, Cermak NM, Stinkens R, et al. Astaxanthin supplementation does not augment fat use or improve endurance performance. Med Sci Sports Exerc. 2013;45(6):1158-65. doi:10.1249/MSS.0b013e31827fddc4
- 9Karppi J, Rissanen TH, Nyyssönen K, et al. Effects of astaxanthin supplementation on lipid peroxidation. Int J Vitam Nutr Res. 2007;77(1):3-11. doi:10.1024/0300-9831.77.1.3
- 10Maleki-Hajiagha A, Aleyasin A, Amidi F. Exploratory pilot trial of astaxanthin supplementation in PCOS patients at risk of OHSS with focus on RAGE-NFκB pathway. Sci Rep. 2026;16(1). doi:10.1038/s41598-026-36449-7
- 11Moqaddam MA, Nemati M, Dara MM, et al. Exploring the Impact of Astaxanthin Supplementation in Conjunction with a 12-Week CrossFit Training Regimen on Selected Adipo-Myokines Levels in Obese Males. Nutrients. 2024;16(17). doi:10.3390/nu16172857
- 12Kumar S, Kumar R, Kumari A, Panwar A. Astaxanthin: A super antioxidant from microalgae and its therapeutic potential. J Basic Microbiol. 2022;62(9):1064-1082. doi:10.1002/jobm.202100391
- 13Stachowiak B, Szulc P. Astaxanthin for the Food Industry. Molecules. 2021;26(9). doi:10.3390/molecules26092666
- 14Villaró S, Ciardi M, Morillas-España A, Sánchez-Zurano A, Acién-Fernández G, Lafarga T. Microalgae Derived Astaxanthin: Research and Consumer Trends and Industrial Use as Food. Foods. 2021;10(10). doi:10.3390/foods10102303
- 15Kishimoto Y, Yoshida H, Kondo K. Potential Anti-Atherosclerotic Properties of Astaxanthin. Mar Drugs. 2016;14(2). doi:10.3390/md14020035
- 16Higuera-Ciapara I, Félix-Valenzuela L, Goycoolea FM. Astaxanthin: a review of its chemistry and applications. Crit Rev Food Sci Nutr. 2006;46(2):185-96. doi:10.1080/10408690590957188
- 17Bhattarai G, So HS, Kieu TTT, Kook SH, Lee JC, Jeon YM. Astaxanthin Inhibits Diabetes-Triggered Periodontal Destruction, Ameliorates Oxidative Complications in STZ-Injected Mice, and Recovers Nrf2-Dependent Antioxidant System. Nutrients. 2021;13(10). doi:10.3390/nu13103575
- 18Brown DR, Gough LA, Deb SK, Sparks SA, McNaughton LR. Astaxanthin in Exercise Metabolism, Performance and Recovery: A Review. Front Nutr. 2017;4:76. doi:10.3389/fnut.2017.00076
- 19Ren P, Wei B, Qin W, Tang Q, Wang Y, Xue C. Impact of astaxanthin on the capacity of gut microbiota to produce tryptophan catabolites. Food Funct. 2025;16(2):524-538. doi:10.1039/d4fo04890c
- 20Zhao M, Ma L, Honda T, et al. Astaxanthin Attenuates Nonalcoholic Steatohepatitis with Downregulation of Osteoprotegerin in Ovariectomized Mice Fed Choline-Deficient High-Fat Diet. Dig Dis Sci. 2023;68(1):155-163. doi:10.1007/s10620-022-07489-6
- 21Chitchumroonchokchai C, Failla ML. Bioaccessibility and intestinal cell uptake of astaxanthin from salmon and commercial supplements. Food Res Int. 2017;99(Pt 2):936-943. doi:10.1016/j.foodres.2016.10.010
- 22Cai Y, Yang S, Zhao J, et al. Mechanism Exploration of Dietary Supplement Astaxanthin on Improving Atherosclerosis through an Integrated Strategy Encompassing Artificial Intelligence Virtual Screening and Experimental Validation. J Agric Food Chem. 2025;73(18):11265-11287. doi:10.1021/acs.jafc.4c11894