E320Antioxidant
Butylated hydroxyanisole (bha)
What the research shows
PrototypeConcerning
in studies of people
1 of 3 health findings on this page · See the findings
A man-made waxy solid from petroleum.
It stops food spoiling by acting as an antioxidant.
Written from English Wikipedia1
- Vegan
- Vegetarian
- EU permitted
What research says
Studies in people
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Concern
Additive intake in young children2
In young children, eating butylated hydroxyanisole from foods like vegetable soups may exceed the safe daily amount.
Animal and lab studies only
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Concern
Blood vessel health7
In lab and animal studies, butylated hydroxyanisole harmed blood vessel cells, but scientists do not yet know if this happens in people.
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Concern
Hormone balance in tissues8
In lab studies, butylated hydroxyanisole blocked an enzyme that controls a hormone, which may raise hormone action in kidneys and placentas.
Study type not stated
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Concern
Health risks of additive4
Several studies show butylated hydroxyanisole may cause thyroid damage, growth and metabolic problems, and cancer.
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Concern
Cell and DNA damage5
Butylated hydroxyanisole (BHA) can cause cell and DNA damage when absorbed in high doses through the gut.
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Open question
Gut bacteria6
Butylated hydroxyanisole changed some gut bacteria genes but not the overall mix.
How it’s made and used
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Food sources of additive3
In Lebanese children aged 9 to 18, bread and biscuits were the main sources of BHA.
The signal at the top counts the findings in people and in animal and lab studies. A concern in studies of people outranks animal and lab studies, and “No concerns” needs at least two findings in people. Findings whose study type is not stated are shown but not counted. This page is a reference, not medical advice. It describes what regulators and published research say. Talk to a doctor or dietitian about your own diet.
Regulatory status
Checked Sep 2026-
United States Permitted FDA 21 CFR 172.110
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European Union Permitted EUR-Lex Reg. (EC) 1333/2008
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United Kingdom Permitted FSA retained EU law
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Canada Permitted Health Canada · Preservatives
Status reflects the named register on the date checked. It is not a safety rating.
How we checkProducts
The 6 most-scanned of 3,465 products on Open Food Facts that list butylated hydroxyanisole (bha).
- Super Noodles Chicken Flavour Batchelors · 90 g 7 additives
- Extra Peppermint Wrigley's · 64 g 10 additives
- Extra Spearmint (46 Pieces) Wrigley's 10 additives
- White Bubblemint Chewing Gum Sugar Free Bottle Pieces Mars · 64 g 14 additives
- 46 Piece Chewing Gum Pot Airwaves · 64 g e 14 additives
- Wrigley's Extra Peppermint Wrigley's · 60 pieces 11 additives
References
- 1Butylated hydroxyanisole. Wikipedia. Accessed September 25, 2026.
- 2Mancini FR, Paul D, Gauvreau J, Volatier JL, Vin K, Hulin M. Dietary exposure to benzoates (E210-E213), parabens (E214-E219), nitrites (E249-E250), nitrates (E251-E252), BHA (E320), BHT (E321) and aspartame (E951) in children less than 3 years old in France. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2015;32(3):293-306. doi:10.1080/19440049.2015.1007535
- 3Soubra L, Sarkis D, Hilan C, Verger P. Dietary exposure of children and teenagers to benzoates, sulphites, butylhydroxyanisol (BHA) and butylhydroxytoluen (BHT) in Beirut (Lebanon). Regul Toxicol Pharmacol. 2007;47(1):68-77. doi:10.1016/j.yrtph.2006.07.005
- 4Zhang XJ, Diao MN, Zhang YF. A review of the occurrence, metabolites and health risks of butylated hydroxyanisole (BHA). J Sci Food Agric. 2023;103(13):6150-6166. doi:10.1002/jsfa.12676
- 5Esazadeh K, Ezzati Nazhad Dolatabadi J, Andishmand H, et al. Cytotoxic and genotoxic effects of tert-butylhydroquinone, butylated hydroxyanisole and propyl gallate as synthetic food antioxidants. Food Sci Nutr. 2024;12(10):7004-7016. doi:10.1002/fsn3.4373
- 6Lemons JMS, Narrowe AB, Firrman J, et al. The food additive butylated hydroxyanisole minimally affects the human gut microbiome ex vivo. Food Chem. 2025;473:143037. doi:10.1016/j.foodchem.2025.143037
- 7Zhan Y, Zhang Y. Butylated hydroxyanisole induces vascular endothelial injury via TFEB-mediated degradation of GPX4 and FTH1. Food Chem Toxicol. 2024;188:114682. doi:10.1016/j.fct.2024.114682
- 8Li L, Wu Y, Wu X, et al. Butylated Hydroxyanisole Potently Inhibits Rat and Human 11β-Hydroxysteroid Dehydrogenase Type 2. Pharmacology. 2016;97(1-2):10-7. doi:10.1159/000441034