E320Antioxidant

Butylated hydroxyanisole (bha)

What the research shows

Prototype

Concerning

in studies of people

1 of 3 health findings on this page · See the findings

A man-made waxy solid from petroleum.

It stops food spoiling by acting as an antioxidant.

Written from English Wikipedia1

  • Vegan
  • Vegetarian
  • EU permitted

What research says

Studies in people

Animal and lab studies only

  • Concern

    Blood vessel health7

    In lab and animal studies, butylated hydroxyanisole harmed blood vessel cells, but scientists do not yet know if this happens in people.

  • Concern

    Hormone balance in tissues8

    In lab studies, butylated hydroxyanisole blocked an enzyme that controls a hormone, which may raise hormone action in kidneys and placentas.

Study type not stated

  • Concern

    Health risks of additive4

    Several studies show butylated hydroxyanisole may cause thyroid damage, growth and metabolic problems, and cancer.

  • Concern

    Cell and DNA damage5

    Butylated hydroxyanisole (BHA) can cause cell and DNA damage when absorbed in high doses through the gut.

  • Open question

    Gut bacteria6

    Butylated hydroxyanisole changed some gut bacteria genes but not the overall mix.

How it’s made and used

The signal at the top counts the findings in people and in animal and lab studies. A concern in studies of people outranks animal and lab studies, and “No concerns” needs at least two findings in people. Findings whose study type is not stated are shown but not counted. This page is a reference, not medical advice. It describes what regulators and published research say. Talk to a doctor or dietitian about your own diet.

Regulatory status

Checked Sep 2026

Status reflects the named register on the date checked. It is not a safety rating.

How we check

Products

The 6 most-scanned of 3,465 products on Open Food Facts that list butylated hydroxyanisole (bha).

  • Super Noodles Chicken Flavour Batchelors · 90 g 7 additives
  • Extra Peppermint Wrigley's · 64 g 10 additives
  • Extra Spearmint (46 Pieces) Wrigley's 10 additives
  • White Bubblemint Chewing Gum Sugar Free Bottle Pieces Mars · 64 g 14 additives
  • 46 Piece Chewing Gum Pot Airwaves · 64 g e 14 additives
  • Wrigley's Extra Peppermint Wrigley's · 60 pieces 11 additives

References

  1. 1Butylated hydroxyanisole. Wikipedia. Accessed September 25, 2026.
  2. 2Mancini FR, Paul D, Gauvreau J, Volatier JL, Vin K, Hulin M. Dietary exposure to benzoates (E210-E213), parabens (E214-E219), nitrites (E249-E250), nitrates (E251-E252), BHA (E320), BHT (E321) and aspartame (E951) in children less than 3 years old in France. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2015;32(3):293-306. doi:10.1080/19440049.2015.1007535
  3. 3Soubra L, Sarkis D, Hilan C, Verger P. Dietary exposure of children and teenagers to benzoates, sulphites, butylhydroxyanisol (BHA) and butylhydroxytoluen (BHT) in Beirut (Lebanon). Regul Toxicol Pharmacol. 2007;47(1):68-77. doi:10.1016/j.yrtph.2006.07.005
  4. 4Zhang XJ, Diao MN, Zhang YF. A review of the occurrence, metabolites and health risks of butylated hydroxyanisole (BHA). J Sci Food Agric. 2023;103(13):6150-6166. doi:10.1002/jsfa.12676
  5. 5Esazadeh K, Ezzati Nazhad Dolatabadi J, Andishmand H, et al. Cytotoxic and genotoxic effects of tert-butylhydroquinone, butylated hydroxyanisole and propyl gallate as synthetic food antioxidants. Food Sci Nutr. 2024;12(10):7004-7016. doi:10.1002/fsn3.4373
  6. 6Lemons JMS, Narrowe AB, Firrman J, et al. The food additive butylated hydroxyanisole minimally affects the human gut microbiome ex vivo. Food Chem. 2025;473:143037. doi:10.1016/j.foodchem.2025.143037
  7. 7Zhan Y, Zhang Y. Butylated hydroxyanisole induces vascular endothelial injury via TFEB-mediated degradation of GPX4 and FTH1. Food Chem Toxicol. 2024;188:114682. doi:10.1016/j.fct.2024.114682
  8. 8Li L, Wu Y, Wu X, et al. Butylated Hydroxyanisole Potently Inhibits Rat and Human 11β-Hydroxysteroid Dehydrogenase Type 2. Pharmacology. 2016;97(1-2):10-7. doi:10.1159/000441034