E170iColour · Stabiliser
Calcium carbonate
What the research shows
Mostly no concerns
most studies in people found no harm or a benefit
What research says
Studies in people
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Open question
How well calcium is absorbed3
Scientists do not yet know whether calcium carbonate needs stomach acid to be absorbed well.
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Benefit
Phosphate levels in dialysis patients5
In dialysis patients, eating cheese made with added calcium carbonate lowered phosphate levels between treatments.
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Benefit
Bone density in teenagers6
In teens with HIV and low vitamin D, calcium carbonate plus vitamin D3 improved bone density.
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Concern
Thyroid hormone absorption7
Taking calcium carbonate within two hours of thyroid pills raised TSH and cholesterol in women.
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Open question
Bone strength in children8
In children with HIV, calcium carbonate with vitamin D3 is being tested to see if it helps bones grow stronger.
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Benefit
Calcium absorption in teen girls9
In teen girls, calcium carbonate supplements helped the body hold onto more calcium than a placebo, but smaller particles were no better.
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Open question
Calcium absorption after stomach surgery10
In people who had gastric bypass, calcium citrate was absorbed better than calcium carbonate.
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No harm found
Calcium absorption from supplements11
In women, calcium carbonate raised blood calcium no more than a placebo pill did.
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No harm found
Blood pressure12
Calcium carbonate did not lower blood pressure in people with mild high blood pressure.
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Concern
Iron absorption from food13
In women, taking calcium carbonate with a meal cut how much iron their bodies absorbed from that food.
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Open question
Bone strength in children with HIV14
In children with HIV, calcium carbonate with vitamin D3 is being tested to see if it helps bones grow stronger.
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Benefit
Bone breakdown after menopause16
In postmenopausal women, calcium carbonate and milk both lowered bone breakdown, and visceral fat did not change this.
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Open question
Child growth after pregnancy supplements19
Calcium carbonate taken in pregnancy led to higher growth signals in boys but lower ones in girls years later.
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Benefit
Calcium absorption after weight-loss surgery20
In people who had weight-loss surgery, calcium citrate raised calcium absorption more than calcium carbonate did.
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Benefit
Bone breakdown in older women21
In older women, calcium citrate lowered bone breakdown markers, while calcium carbonate did not change them.
Found in some samples or products
These come from where it was grown, how it was processed or cooked, or what it was made into. They are not about the ingredient itself, so the signal does not count them.
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Aluminium in infant formula24
Calcium carbonate used in infant formula can carry aluminium, which the experts said is a concern.
How it’s made and used
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How much calcium the body absorbs4
In people, calcium from calcium carbonate was absorbed about as well as from another calcium supplement.
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Calcium absorption from soymilk15
In women, the body absorbed calcium from calcium carbonate-fortified soymilk as well as from cow's milk.
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Kidney stone risk17
In eight healthy men, calcium carbonate plus citrate had an added effect on one urine stone risk factor.
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Bone health after stomach surgery18
In people who had gastric bypass, calcium carbonate and calcium citrate changed parathyroid hormone levels about the same.
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Blood calcium levels22
Calcium carbonate supplements raised calcium in the blood for hours after each dose, and this repeated with daily use.
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What it does in food23
Calcium carbonate is used in food to carry nutrients and hold mixtures and gels together.
The signal at the top counts the findings in people and in animal and lab studies. A concern in studies of people outranks animal and lab studies, and “No concerns” needs at least one finding in people. When most findings in people point one way, the page leans that way (“Mostly”), and every finding is still shown. Findings whose study type is not stated are shown but not counted. This page is a reference, not medical advice. It describes what regulators and published research say. Talk to a doctor or dietitian about your own diet.
Regulatory status
Checked Sep 2026-
United States Permitted FDA 21 CFR 73.70
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Canada Permitted Health Canada · Colouring Agents
Status reflects the named register on the date checked. It is not a safety rating. A country appears here once we've found this ingredient on its official list.
How we checkProducts
The 6 most-scanned of 17,212 products on Open Food Facts that list calcium carbonate.
- Geröstete Mandel Ohne Zucker alpro · 1 l 3 additives
- White Ciabatta Sourdough Bread Jason's Sourdough · 580 g 0 additives
- Sliced White Sourdough Bread with Grains & Seeds Ciabattin Jason's · 580 g 0 additives
- sourdough bread jason's sourdough · 450 g 0 additives
- Seeded Sourdough Bread Specially Selected · 500 g 0 additives
- JASON'S SOURDOUGH JASON'S SOURDOUGH · 450 g 0 additives
References
- 1Calcium carbonate: ingredient taxonomy entry. Open Food Facts.
- 2Calcium carbonate. Wikipedia. Accessed September 26, 2026. CC BY-SA 4.0.
- 3de Jonge HJ, Gans RO, Huls G. [Calcium suppletion for patients who use gastric acid inhibitors: calcium citrate or calcium carbonate?]. Ned Tijdschr Geneeskd. 2012;156(34):A4343.
- 4Wiria M, Tran HM, Nguyen PHB, Valencia O, Dutta S, Pouteau E. Relative bioavailability and pharmacokinetic comparison of calcium glucoheptonate with calcium carbonate. Pharmacol Res Perspect. 2020;8(2):e00589. doi:10.1002/prp2.589
- 5Ardissino G, Matta R, Patricelli M, et al. Calcium carbonate-enriched cheese to improve nutrition, compliance and phosphorus control in patients on kidney replacement therapy. J Nephrol. 2022;35(1):305-309. doi:10.1007/s40620-021-01102-1
- 6Ferrand RA, Dzavakwa NV, Bandason T, et al. Impact of high-dose vitamin D and calcium carbonate supplementation on bone density in adolescents living with HIV: a randomised, placebo-controlled trial. Lancet Child Adolesc Health. 2026;10(2):111-121. doi:10.1016/S2352-4642(25)00301-3
- 7Morini E, Catalano A, Lasco A, Morabito N, Benvenga S. L-thyroxine malabsorption due to calcium carbonate impairs blood pressure, total cholesterolemia, and fasting glycemia. Endocrine. 2019;64(2):284-292. doi:10.1007/s12020-018-1798-7
- 8Dzavakwa NV, Chisenga M, McHugh G, et al. Vitamin D(3) and calcium carbonate supplementation for adolescents with HIV to reduce musculoskeletal morbidity and immunopathology (VITALITY trial): study protocol for a randomised placebo-controlled trial. Trials. 2022;23(1):78. doi:10.1186/s13063-021-05985-0
- 9Elble AE, Hill KM, Park CY, Martin BR, Peacock M, Weaver CM. Effect of calcium carbonate particle size on calcium absorption and retention in adolescent girls. J Am Coll Nutr. 2011;30(3):171-7. doi:10.1080/07315724.2011.10719957
- 10Tondapu P, Provost D, Adams-Huet B, Sims T, Chang C, Sakhaee K. Comparison of the absorption of calcium carbonate and calcium citrate after Roux-en-Y gastric bypass. Obes Surg. 2009;19(9):1256-61. doi:10.1007/s11695-009-9850-6
- 11Hanzlik RP, Fowler SC, Fisher DH. Relative bioavailability of calcium from calcium formate, calcium citrate, and calcium carbonate. J Pharmacol Exp Ther. 2005;313(3):1217-22. doi:10.1124/jpet.104.081893
- 12Nowson C, Morgan T. Effect of calcium carbonate on blood pressure in normotensive and hypertensive people. Hypertension. 1989;13(6 Pt 1):630-9. doi:10.1161/01.hyp.13.6.630
- 13Dawson-Hughes B, Seligson FH, Hughes VA. Effects of calcium carbonate and hydroxyapatite on zinc and iron retention in postmenopausal women. Am J Clin Nutr. 1986;44(1):83-8. doi:10.1093/ajcn/44.1.83
- 14Dzavakwa NV, Chisenga M, McHugh G, et al. Update: Vitamin D(3) and calcium carbonate supplementation for adolescents with HIV to reduce musculoskeletal morbidity and immunopathology (VITALITY trial): study protocol for a randomised placebo-controlled trial. Trials. 2024;25(1):499. doi:10.1186/s13063-024-08342-z
- 15Zhao Y, Martin BR, Weaver CM. Calcium bioavailability of calcium carbonate fortified soymilk is equivalent to cow's milk in young women. J Nutr. 2005;135(10):2379-82. doi:10.1093/jn/135.10.2379
- 16Sharma DK, Anderson PH, Morris HA, Clifton PM. Acute C-Terminal Crosslinking Telopeptide of Type I Collagen (CTX-1) Suppression with Milk Calcium or Calcium Carbonate Is Independent of Visceral Fat in a Randomized Crossover Study in Lean and Overweight Postmenopausal Women. J Nutr. 2022;152(4):1006-1014. doi:10.1093/jn/nxab384
- 17Allie S, Rodgers A. Effects of calcium carbonate, magnesium oxide and sodium citrate bicarbonate health supplements on the urinary risk factors for kidney stone formation. Clin Chem Lab Med. 2003;41(1):39-45. doi:10.1515/CCLM.2003.008
- 18Ring Madsen L, Espersen R, Rejnmark L, Richelsen B. Effect of calcium citrate vs calcium carbonate on elevated parathyroid hormone after Roux-en-Y gastric bypass. A double-blinded, randomized trial. Clin Endocrinol (Oxf). 2018;89(6):734-741. doi:10.1111/cen.13836
- 19Prentice A, Ward KA, Nigdikar S, Hawkesworth S, Moore SE. Pregnancy supplementation of Gambian mothers with calcium carbonate alters mid-childhood IGF1 in a sex-specific manner. Bone. 2019;120:314-320. doi:10.1016/j.bone.2018.11.011
- 20Hany M, Wuyts S, Abouelnasr AA, et al. Comparison of calcium citrate and calcium carbonate absorption in patients with a Roux-en-Y gastric bypass, sleeve gastrectomy, and one-anastomosis gastric bypass: a double-blind, randomized cross-over trial. Surg Obes Relat Dis. 2025;21(4):471-481. doi:10.1016/j.soard.2024.10.034
- 21Kenny AM, Prestwood KM, Biskup B, et al. Comparison of the effects of calcium loading with calcium citrate or calcium carbonate on bone turnover in postmenopausal women. Osteoporos Int. 2004;15(4):290-4. doi:10.1007/s00198-003-1567-0
- 22Bristow SM, Gamble GD, Stewart A, et al. Acute and 3-month effects of microcrystalline hydroxyapatite, calcium citrate and calcium carbonate on serum calcium and markers of bone turnover: a randomised controlled trial in postmenopausal women. Br J Nutr. 2014;112(10):1611-20. doi:10.1017/S0007114514002785
- 23Dong Y, Liu Z, Lan T, Zhang Y, Sui X. Calcium carbonate particles: Template-driven structural design and functional innovation applications in food systems. Food Chem. 2025;485:144447. doi:10.1016/j.foodchem.2025.144447
- 24Younes M, Aquilina G, Castle L, et al. Re-evaluation of calcium carbonate (E 170) as a food additive in foods for infants below 16 weeks of age and follow-up of its re-evaluation as food additive for uses in foods for all population groups. EFSA J. 2023;21(7):e08106. doi:10.2903/j.efsa.2023.8106