Calcium pantothenate

What the research shows

No concerns

none of the findings here link it to harm

A form of vitamin B5 used in supplements and animal feed.

It is more stable than other forms, so products last longer on the shelf.1

  • Vegan
  • Vegetarian

What research says

Studies in people

  • No harm found

    Rare vitamin shortfall2

    Pantothenic acid deficiency is rare, and no health concerns related to it were found.

  • Benefit

    Diet and inflammation marker4

    In older adults in South Korea, eating more pantothenic acid was linked to lower levels of a marker of inflammation over time.

  • No harm found

    Vitamin levels in teens5

    In 63 healthy teens, eating less pantothenic acid than suggested still came with normal blood levels.

How it’s made and used

  • Exercise performance3

    In trained male cyclists, 16 weeks of pantothenic acid did not change muscle CoASH or exercise performance.

  • Vitamin levels in pregnancy6

    In pregnant and breastfeeding women, average blood pantothenate was lower than in other women.

  • Vitamin excretion in urine7

    In people eating a peanut butter diet, taking pantothenic acid raised pantothenic acid in urine, and taking niacin lowered it.

  • Vitamin levels in the body8

    People eating little pantothenic acid had less of it in their blood and urine than those taking a supplement.

  • Vitamin levels in older adults9

    In older people studied, those taking pantothenic acid supplements had higher levels of it in their urine.

The signal at the top counts the findings in people and in animal and lab studies. A concern in studies of people outranks animal and lab studies, and “No concerns” needs at least one finding in people. When most findings in people point one way, the page leans that way (“Mostly”), and every finding is still shown. Findings whose study type is not stated are shown but not counted. This page is a reference, not medical advice. It describes what regulators and published research say. Talk to a doctor or dietitian about your own diet.

Products

The 6 most-scanned of 2,927 products on Open Food Facts that list calcium pantothenate.

  • Energy Drink Red Bull · 250 ml 2 additives
  • Oatmeal Squares Quaker · 500 g 4 additives
  • Multi Grain Cheerios Cheerios · 510 g 2 additives
  • Unsweetened Organic Fortified Soy Beverage Natura · 946 mL 0 additives
  • SPARKLING ORANGE CELSIUS · 12 FL OZ (355 mL) 2 additives
  • Lait de soya Kirkland Signature · 946 ml 1 additive

References

  1. 1Pantothenic acid. Wikipedia. Accessed September 26, 2026. CC BY-SA 4.0.
  2. 2Freese R, Aarsland TE, Bjørkevoll M. Pantothenic acid - a scoping review for Nordic Nutrition Recommendations 2023. Food Nutr Res. 2023;67. doi:10.29219/fnr.v67.10255
  3. 3Whitfield J, Harris RC, Broad EM, et al. Chronic pantothenic acid supplementation does not affect muscle coenzyme A content or cycling performance. Appl Physiol Nutr Metab. 2021;46(3):280-283. doi:10.1139/apnm-2020-0692
  4. 4Jung S, Kim MK, Choi BY. The long-term relationship between dietary pantothenic acid (vitamin B(5)) intake and C-reactive protein concentration in adults aged 40 years and older. Nutr Metab Cardiovasc Dis. 2017;27(9):806-816. doi:10.1016/j.numecd.2017.05.008
  5. 5Eissenstat BR, Wyse BW, Hansen RG. Pantothenic acid status of adolescents. Am J Clin Nutr. 1986;44(6):931-7. doi:10.1093/ajcn/44.6.931
  6. 6Song WO, Wyse BW, Hansen RG. Pantothenic acid status of pregnant and lactating women. J Am Diet Assoc. 1985;85(2):192-8.
  7. 7Duke ML, Kies C, Fox HM. Niacin and pantothenic acid excretions of humans fed a low-methionine, plant-based diet. J Nutr Sci Vitaminol (Tokyo). 1977;23(6):481-9. doi:10.3177/jnsv.23.481
  8. 8Fry PC, Fox HM, Tao HG. Metabolic response to a pantothenic acid deficient diet in humans. J Nutr Sci Vitaminol (Tokyo). 1976;22(4):339-46. doi:10.3177/jnsv.22.339
  9. 9Srinivasan V, Christensen N, Wyse BW, Hansen RG. Pantothenic acid nutritional status in the elderly--institutionalized and noninstitutionalized. Am J Clin Nutr. 1981;34(9):1736-42. doi:10.1093/ajcn/34.9.1736