Cane sugar

What the research shows

Concerning

in studies of people

A sweetener extracted from sugarcane.

It is used to sweeten foods and drinks like cookies, cakes, coffee, and tea.1

What research says

Studies in people

  • Concern

    Liver fat production2

    In healthy men, drinks with fructose or sucrose increased the liver's fat-making more than glucose drinks did.

  • Concern

    Heart and blood health4

    In overweight people, sucrose in drinks raised homocysteine and total cholesterol.

  • Concern

    Body weight changes5

    In adults with overweight, drinking sucrose-sweetened drinks daily for 12 weeks led to weight gain.

  • Concern

    Pregnancy blood pressure risk6

    In pregnant women, high sucrose intake was linked to a higher risk of preeclampsia.

Animal and lab studies only

  • Concern

    Body fat and liver11

    In mice, drinking sucrose water raised body fat, especially in males, without changing insulin response.

  • Concern

    Hunger brain signals12

    In animal studies, a high-sucrose diet blunted the silencing of hunger-promoting brain cells after glucose.

Study type not stated

  • Concern

    Tooth decay10

    Eating cane sugar often, and in large amounts, is linked to tooth decay, especially in children's new teeth.

How it’s made and used

The signal at the top counts the findings in people and in animal and lab studies. A concern in studies of people outranks animal and lab studies, and “No concerns” needs at least one finding in people. When most findings in people point one way, the page leans that way (“Mostly”), and every finding is still shown. Findings whose study type is not stated are shown but not counted. This page is a reference, not medical advice. It describes what regulators and published research say. Talk to a doctor or dietitian about your own diet.

References

  1. 1Sugar. Wikipedia. Accessed September 26, 2026. CC BY-SA 4.0.
  2. 2Geidl-Flueck B, Hochuli M, Németh Á, et al. Fructose- and sucrose- but not glucose-sweetened beverages promote hepatic de novo lipogenesis: A randomized controlled trial. J Hepatol. 2021;75(1):46-54. doi:10.1016/j.jhep.2021.02.027
  3. 3Sousa Lima R, Cazelatto de Medeiros A, André Bolini HM. Sucrose replacement: a sensory profile and time-intensity analysis of a tamarind functional beverage with artificial and natural non-nutritive sweeteners. J Sci Food Agric. 2021;101(2):593-602. doi:10.1002/jsfa.10671
  4. 4Zafrilla P, Masoodi H, Cerdá B, García-Viguera C, Villaño D. Biological effects of stevia, sucralose and sucrose in citrus-maqui juices on overweight subjects. Food Funct. 2021;12(18):8535-8543. doi:10.1039/d1fo01160j
  5. 5Higgins KA, Mattes RD. A randomized controlled trial contrasting the effects of 4 low-calorie sweeteners and sucrose on body weight in adults with overweight or obesity. Am J Clin Nutr. 2019;109(5):1288-1301. doi:10.1093/ajcn/nqy381
  6. 6Clausen T, Slott M, Solvoll K, Drevon CA, Vollset SE, Henriksen T. High intake of energy, sucrose, and polyunsaturated fatty acids is associated with increased risk of preeclampsia. Am J Obstet Gynecol. 2001;185(2):451-8. doi:10.1067/mob.2001.116687
  7. 7Odell OJ, Podlogar T, Wallis GA. Comparable Exogenous Carbohydrate Oxidation from Lactose or Sucrose during Exercise. Med Sci Sports Exerc. 2020;52(12):2663-2672. doi:10.1249/MSS.0000000000002426
  8. 8Flad E, Teysseire F, Budzinska A, et al. Erythritol, sucrose, and sucralose elicit similar reward responses after flavor preference learning in healthy humans. Physiol Behav. 2026;314:115394. doi:10.1016/j.physbeh.2026.115394
  9. 9van der Sman RGM, Renzetti S. Understanding functionality of sucrose in biscuits for reformulation purposes. Crit Rev Food Sci Nutr. 2019;59(14):2225-2239. doi:10.1080/10408398.2018.1442315
  10. 10Sheiham A. Sucrose and dental caries. Nutr Health. 1987;5(1-2):25-9. doi:10.1177/026010608700500205
  11. 11Stephenson EJ, Stayton AS, Sethuraman A, et al. Chronic intake of high dietary sucrose induces sexually dimorphic metabolic adaptations in mouse liver and adipose tissue. Nat Commun. 2022;13(1):6062. doi:10.1038/s41467-022-33840-6
  12. 12Lorch CM, Hayes NW, Xia JL, et al. Sucrose overconsumption impairs AgRP neuron dynamics and promotes palatable food intake. Cell Rep. 2024;43(2):113675. doi:10.1016/j.celrep.2024.113675