Chlorella

What the research shows

No concerns

none of the findings here link it to harm

A tiny green algae.

It has been considered as a source of food and energy.12

What research says

Studies in people

  • Benefit

    Iron levels in the blood3

    In people and animals, chlorella raised iron levels and helped red blood cells, but longer human studies are needed.

  • Open question

    Heart health4

    Chlorella may help lower inflammation and oxidative stress, but studies on heart risk factors show mixed results.

  • Benefit

    Heart and blood vessel health5

    In people with mildly high cholesterol, daily chlorella supplements lowered blood triglycerides and total cholesterol.

  • No harm found

    Blood pressure and cholesterol6

    In people, chlorella supplements did not change blood pressure or cholesterol levels.

  • Benefit

    Heart and blood sugar health7

    Chlorella may improve cholesterol, blood pressure and blood sugar, but scientists do not yet know which compounds in it do this.

  • Benefit

    Heart and blood health8

    In people, taking chlorella lowered cholesterol, blood pressure and blood sugar, but not triglycerides, good cholesterol or weight.

  • Benefit

    Blood sugar and cholesterol9

    In people, chlorella supplements have been suggested to help lower blood sugar and cholesterol.

  • Benefit

    Menstrual pain relief11

    In women with period pain, taking chlorella reduced how bad and how long the pain lasted.

  • Benefit

    Clearing cooking chemicals12

    In people, chlorella may help clear some harmful cooking chemicals from the body, but scientists do not yet know for sure.

  • No harm found

    Food allergy potential13

    Chlorella did not cause allergic skin reactions in people, and animal studies found no DNA damage.

  • Benefit

    Blood pressure control14

    In people with slightly high blood pressure, GABA-rich chlorella taken twice daily for 12 weeks lowered systolic blood pressure.

  • Open question

    DNA damage in smokers15

    In smokers, chlorella raised blood antioxidants, but DNA damage dropped with placebo too, so the benefit is unclear.

  • Open question

    Immune response to flu shot16

    Chlorella did not raise flu-shot antibodies overall, though people 50 to 55 saw a rise.

  • Open question

    Exercise recovery after cycling17

    In people, taking chlorella for two days lowered blood lactate after cycling but did not boost peak fitness.

Animal and lab studies only

  • Benefit

    Skin aging and repair22

    In lab and animal studies, chlorella fractions may support cell repair under stress, but human evidence is lacking.

  • Benefit

    Gut bacteria balance23

    In lab studies, chlorella helped gut bacteria make more good acids and crowd out harmful ones.

  • Benefit

    Skin allergy symptoms24

    In mice, chlorella lessened atopic dermatitis-like skin symptoms, but whether it helps people is not yet known.

Study type not stated

Found in some samples or products

These come from where it was grown, how it was processed or cooked, or what it was made into. They are not about the ingredient itself, so the signal does not count them.

Single cases of misuse or overdose

One person or one incident, such as an accidental overdose or a mistake in a kitchen or factory. They are real, but a single case does not show what happens at normal amounts, so the signal does not count them.

The signal at the top counts the findings in people and in animal and lab studies. A concern in studies of people outranks animal and lab studies, and “No concerns” needs at least one finding in people. When most findings in people point one way, the page leans that way (“Mostly”), and every finding is still shown. Findings whose study type is not stated are shown but not counted. This page is a reference, not medical advice. It describes what regulators and published research say. Talk to a doctor or dietitian about your own diet.

Products

The 6 most-scanned of 378 products on Open Food Facts that list chlorella.

  • Green Machine Super Smoothie Naked · 2 servings, 300 g 0 additives
  • organic supergreens fruits & vegetables zena greens 4 additives
  • CHEDDY MAC CREAMY CHEDDAR AND MACARONI GOODLES · 6 oz 3 additives
  • Green Machine Super Smoothie Naked · 750 ml 0 additives
  • Shella Good Aged White Cheddar and Shells Goodles · 6 oz 2 additives
  • greens & superfoods Bloom 5 additives

References

  1. 1chlorella: ingredient taxonomy entry. Open Food Facts.
  2. 2Chlorella. Wikipedia. Accessed September 29, 2026. CC BY-SA 4.0.
  3. 3Lacurezeanu A, Vodnar DC. Arthrospira platensis and Chlorella vulgaris Consumption on Iron Status: A Systematic Review of In Vivo Studies. Mol Nutr Food Res. 2025;69(24):e70318. doi:10.1002/mnfr.70318
  4. 4Barghchi H, Dehnavi Z, Nattagh-Eshtivani E, et al. The effects of Chlorella vulgaris on cardiovascular risk factors: A comprehensive review on putative molecular mechanisms. Biomed Pharmacother. 2023;162:114624. doi:10.1016/j.biopha.2023.114624
  5. 5Heo Y, Kim MY, Cho JY. Chlorella vulgaris, a representative edible algae as integrative and alternative medicine. Integr Med Res. 2026;15(1):101228. doi:10.1016/j.imr.2025.101228
  6. 6Pinto-Leite M, Martins D, Ferreira AC, et al. The Role of Chlorella and Spirulina as Adjuvants of Cardiovascular Risk Factor Control: A Systematic Review and Meta-Analysis of Randomised Controlled Trials. Nutrients. 2025;17(6). doi:10.3390/nu17060943
  7. 7Bito T, Okumura E, Fujishima M, Watanabe F. Potential of Chlorella as a Dietary Supplement to Promote Human Health. Nutrients. 2020;12(9). doi:10.3390/nu12092524
  8. 8Fallah AA, Sarmast E, Habibian Dehkordi S, et al. Effect of Chlorella supplementation on cardiovascular risk factors: A meta-analysis of randomized controlled trials. Clin Nutr. 2018;37(6 Pt A):1892-1901. doi:10.1016/j.clnu.2017.09.019
  9. 9Panahi Y, Darvishi B, Jowzi N, Beiraghdar F, Sahebkar A. Chlorella vulgaris: A Multifunctional Dietary Supplement with Diverse Medicinal Properties. Curr Pharm Des. 2016;22(2):164-73. doi:10.2174/1381612822666151112145226
  10. 10Jitsukawa K, Suizu R, Hidano A. Chlorella photosensitization. New phytophotodermatosis. Int J Dermatol. 1984;23(4):263-8. doi:10.1111/j.1365-4362.1984.tb01245.x
  11. 11Haidari F, Homayouni F, Helli B, Haghighizadeh MH, Farahmandpour F. Effect of chlorella supplementation on systematic symptoms and serum levels of prostaglandins, inflammatory and oxidative markers in women with primary dysmenorrhea. Eur J Obstet Gynecol Reprod Biol. 2018;229:185-189. doi:10.1016/j.ejogrb.2018.08.578
  12. 12Lee I, Tran M, Evans-Nguyen T, et al. Detoxification of chlorella supplement on heterocyclic amines in Korean young adults. Environ Toxicol Pharmacol. 2015;39(1):441-6. doi:10.1016/j.etap.2014.11.015
  13. 13Szabo NJ, Matulka RA, Chan T. Safety evaluation of Whole Algalin Protein (WAP) from Chlorella protothecoides. Food Chem Toxicol. 2013;59:34-45. doi:10.1016/j.fct.2013.05.035
  14. 14Shimada M, Hasegawa T, Nishimura C, et al. Anti-hypertensive effect of gamma-aminobutyric acid (GABA)-rich Chlorella on high-normal blood pressure and borderline hypertension in placebo-controlled double blind study. Clin Exp Hypertens. 2009;31(4):342-54. doi:10.1080/10641960902977908
  15. 15Lee SH, Kang HJ, Lee HJ, Kang MH, Park YK. Six-week supplementation with Chlorella has favorable impact on antioxidant status in Korean male smokers. Nutrition. 2010;26(2):175-83. doi:10.1016/j.nut.2009.03.010
  16. 16Halperin SA, Smith B, Nolan C, Shay J, Kralovec J. Safety and immunoenhancing effect of a Chlorella-derived dietary supplement in healthy adults undergoing influenza vaccination: randomized, double-blind, placebo-controlled trial. CMAJ. 2003;169(2):111-7.
  17. 17White H, Gurney T. Chlorella Supplementation Reduces Blood Lactate Concentration and Increases O(2) Pulse during Submaximal and Maximal Cycling in Young Healthy Adults. Nutrients. 2024;16(5). doi:10.3390/nu16050697
  18. 18Bagryantseva OV, Mazo VK, Kochetkova AA, Khotimchenko SA, Petrov NA. [Chlorella (Chlorella sp.): composition, cultivation technologies and food safety]. Vopr Pitan. 2025;94(5):24-33. doi:10.33029/0042-8833-2025-94-5-24-33
  19. 19Wang CA, Onyeaka H, Miri T, Soltani F. Chlorella vulgaris as a food substitute: Applications and benefits in the food industry. J Food Sci. 2024;89(12):8231-8247. doi:10.1111/1750-3841.17529
  20. 20Rzeski W, Rzeska W. Chlorella and Arthrospira (Spirulina) as Multi-Pathway Biological Response Modulators: Molecular Mechanisms, Signaling Pathways and Clinical Evidence. Molecules. 2026;31(10). doi:10.3390/molecules31101595
  21. 21Shah MAR, Gao F, Zhu F, et al. Chlorella vulgaris as a functional food and nutraceutical: bioactive composition, health-promoting mechanisms, applications, and current challenges. Food Funct. 2026;17(13):5824-5841. doi:10.1039/d6fo00663a
  22. 22Rzeski W, Rzeska W. Chlorella Growth Factor: Biochemical Identity, Redox-Active Mechanisms, Nutritional Relevance, and Translational Implications. Nutrients. 2026;18(8). doi:10.3390/nu18081250
  23. 23Bañares C, Paterson S, Gómez-Garre D, et al. Modulation of Gut Microbiota and Short-Chain Fatty Acid Production by Simulated Gastrointestinal Digests from Microalga Chlorella vulgaris. Int J Mol Sci. 2025;26(6). doi:10.3390/ijms26062754
  24. 24Kang H, Lee CH, Kim JR, et al. Chlorella vulgaris Attenuates Dermatophagoides Farinae-Induced Atopic Dermatitis-Like Symptoms in NC/Nga Mice. Int J Mol Sci. 2015;16(9):21021-34. doi:10.3390/ijms160921021