E330Antioxidant · Sequestrant
Citric acid
What the research shows
Concerning
in animal and lab studies only
A colorless weak organic acid that occurs naturally in citrus fruits.1
- Vegan
- Vegetarian
- EU permitted
What research says
Studies in people
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Benefit
Body fat in overweight adults2
In people with high body fat, drinking tea with citric acid and other ingredients was linked to less body fat.
-
Open question
Iron absorption from toddler milk3
In 15 women, iron in toddler milk with citric acid was absorbed about 20%, more than from fortified cow's milk.
Animal and lab studies only
-
Benefit
Iron absorption from food6
In lab studies, citric acid helped iron from blood clam proteins get taken up by cells.
-
Concern
Tooth enamel erosion7
In lab studies, citric acid soft drinks softened tooth enamel, but some added food polymers seemed to form a protective layer.
Study type not stated
-
Open question
Food industry uses4
Citric acid is used widely in food and other industries, and scientists say much about it is still unexplored.
-
Concern
Iron levels in the body5
Citric acid may help the body take in too much iron, which some scientists link to heart disease and diabetes.
The signal at the top counts the findings in people and in animal and lab studies. A concern in studies of people outranks animal and lab studies, and “No concerns” needs at least one finding in people. When most findings in people point one way, the page leans that way (“Mostly”), and every finding is still shown. Findings whose study type is not stated are shown but not counted. This page is a reference, not medical advice. It describes what regulators and published research say. Talk to a doctor or dietitian about your own diet.
What expert reviews concluded
Expert panels that weigh all the research. Shown for context: the signal at the top does not count them.
-
UN and WHO food additive experts (JECFA), 1973
No daily limit needed (“ADI not specified”, JECFA’s term for very low toxicity).
Regulatory status
Checked Sep 2026-
United States Permitted FDA 21 CFR 184.1033
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European Union Permitted EUR-Lex Reg. (EC) 1333/2008
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United Kingdom Permitted FSA retained EU law
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Canada Permitted Health Canada · Other Accepted Uses
Status reflects the named register on the date checked. It is not a safety rating.
How we checkProducts
The 6 most-scanned of 112,190 products on Open Food Facts that list citric acid.
- Cappy PULPY Coca cola · 1 L 9 additives
- Mayonnaise recette originale Star · 280 ml 17 dh 5 additives
- Confiture d'abricot Delicia · 430 1 additive
- Granola L'Original LU · 200 g e 5 additives
- Natur mit Kokosnuss alpro · 0,5 kg 4 additives
- Momo black Excelo · 36 g 6 additives
References
- 1Citric acid. Wikipedia. Accessed September 26, 2026. CC BY-SA 4.0.
- 2Muroyama K, Murosaki S, Yamamoto Y, Ishijima A, Toh Y. Effects of intake of a mixture of thiamin, arginine, caffeine, and citric acid on adiposity in healthy subjects with high percent body fat. Biosci Biotechnol Biochem. 2003;67(11):2325-33. doi:10.1271/bbb.67.2325
- 3Pizarro F, Olivares M, Maciero E, Krasnoff G, Cócaro N, Gaitan D. Iron Absorption from Two Milk Formulas Fortified with Iron Sulfate Stabilized with Maltodextrin and Citric Acid. Nutrients. 2015;7(11):8952-9. doi:10.3390/nu7115448
- 4Książek E. Citric Acid: Properties, Microbial Production, and Applications in Industries. Molecules. 2023;29(1). doi:10.3390/molecules29010022
- 5Crawford RD. Proposed role for a combination of citric acid and ascorbic acid in the production of dietary iron overload: a fundamental cause of disease. Biochem Mol Med. 1995;54(1):1-11. doi:10.1006/bmme.1995.1001
- 6Sun B, Tan B, Sun N, et al. Effect of ascorbic acid and citric acid on bioavailability of iron from Tegillarca granosa via an in vitro digestion/Caco-2 cell culture system. Food Funct. 2021;12(22):11491-11502. doi:10.1039/d1fo01650d
- 7Beyer M, Reichert J, Heurich E, Jandt KD, Sigusch BW. Pectin, alginate and gum arabic polymers reduce citric acid erosion effects on human enamel. Dent Mater. 2010;26(9):831-9. doi:10.1016/j.dental.2010.04.008