Clarified butter
What the research shows
Mostly no concerns
most studies in people found no harm or a benefit
What research says
Studies in people
-
Concern
Heart risk from fats4
In people, eating ghee raised a blood fat linked to heart risk more than olive oil did.
-
No harm found
Blood cholesterol levels5
Eating ghee in a vegetarian diet generally did not change blood cholesterol in healthy young people, though a few responded differently.
-
Benefit
Heart disease risk6
Men who ate more ghee each month had less heart disease, though scientists cannot say ghee caused this.
-
Open question
Cholesterol levels in adults7
In healthy young adults, eating ghee raised total and HDL cholesterol but not their ratio.
Animal and lab studies only
-
Benefit
Body's inflammation signals8
In animal studies, eating ghee lowered several inflammation signals in the rats' blood and immune cells.
Found in some samples or products
These come from where it was grown, how it was processed or cooked, or what it was made into. They are not about the ingredient itself, so the signal does not count them.
-
Swelling outbreak from food3
In 1987, families in India who ate ghee contaminated with sanguinarine fell ill with epidemic dropsy.
-
Heart artery disease9
Ghee, a clarified butter used in Indian cooking, was found to contain cholesterol oxides, which may help explain high heart disease rates.
The signal at the top counts the findings in people and in animal and lab studies. A concern in studies of people outranks animal and lab studies, and “No concerns” needs at least one finding in people. When most findings in people point one way, the page leans that way (“Mostly”), and every finding is still shown. Findings whose study type is not stated are shown but not counted. This page is a reference, not medical advice. It describes what regulators and published research say. Talk to a doctor or dietitian about your own diet.
Products
The 6 most-scanned of 339 products on Open Food Facts that list clarified butter.
- CHOCO LEIBNIZ milk Bahlsen · 111 g 4 additives
- CHOCO LEIBNIZ Dark Bahlsen · 111 g 4 additives
- Organic Naan Crackers Trader Joe's · 10 oz 2 additives
- Cookies chocolate Chip Sondey · 225 g 1 additive
- Muesli Bars Chocolate & Banana Crownfield · 200 g 2 additives
- MINI NAAN ORIGINAL Stonefire · 28.6oz 4 additives
References
- 1clarified butter: ingredient taxonomy entry. Open Food Facts.
- 2Butterfat. Wikipedia. Accessed September 29, 2026. CC BY-SA 4.0.
- 3Narasimhan C, T JG, Thomas G, Israel J, Rao PS, Pulimood BM. Epidemic dropsy in Andhra Pradesh due to contaminated ghee. J Assoc Physicians India. 1991;39(10):749-50.
- 4Mohammadi Hosseinabadi S, Nasrollahzadeh J. Effects of diets rich in ghee or olive oil on cardiometabolic risk factors in healthy adults: a two-period, crossover, randomised trial. Br J Nutr. 2022;128(9):1720-1729. doi:10.1017/S0007114521004645
- 5Shankar SR, Bijlani RL, Baveja T, et al. Effect of partial replacement of visible fat by ghee (clarified butter) on serum lipid profile. Indian J Physiol Pharmacol. 2002;46(3):355-60.
- 6Gupta R, Prakash H. Association of dietary ghee intake with coronary heart disease and risk factor prevalence in rural males. J Indian Med Assoc. 1997;95(3):67-9, 83.
- 7Shankar SR, Yadav RK, Ray RB, et al. Serum lipid response to introducing ghee as a partial replacement for mustard oil in the diet of healthy young Indians. Indian J Physiol Pharmacol. 2005;49(1):49-56.
- 8Vijaya Kumar M, Sambaiah K, Lokesh BR. The anhydrous milk fat, ghee, lowers serum prostaglandins and secretion of leukotrienes by rat peritoneal macrophages. Prostaglandins Leukot Essent Fatty Acids. 1999;61(4):249-54. doi:10.1054/plef.1999.0097
- 9Jacobson MS. Cholesterol oxides in Indian ghee: possible cause of unexplained high risk of atherosclerosis in Indian immigrant populations. Lancet. 1987;2(8560):656-8. doi:10.1016/s0140-6736(87)92443-3