Cottonseed
What the research shows
PrototypeNo concerns
none of the findings here link it to harm
3 health findings on this page, 2 in people · See the findings
The seed of the cotton plant.
Written from Open Food Facts taxonomy1
What research says
Studies in people
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Benefit
Cholesterol levels2
In people, cottonseed oil lowered LDL cholesterol and triglycerides compared with olive oil, but only a few small studies exist.
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Benefit
Appetite and weight3
In adults with high cholesterol, cottonseed oil led to more fullness and lower reported eating than olive oil.
Animal and lab studies only
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Benefit
Gut inflammation and scarring8
In animal studies, cottonseed oil eased gut inflammation and scarring in mice with colitis.
Study type not stated
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Benefit
Heart and inflammation4
Cottonseed oil is rich in vitamin E and fats that may support heart health and ease inflammation.
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Benefit
Cooking oil uses5
Cottonseed oil is used for cooking and food manufacturing, and may promote health benefits.
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Benefit
Heart and metabolic health7
Recent evidence suggests cottonseed oil may improve heart and metabolic risk factors, but questions remain.
How it’s made and used
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nutrient loss in processing6
Cottonseed oil is widely used in frying and baking, but keeping nutrients in it during processing remains a challenge.
The signal at the top counts the findings in people and in animal and lab studies. A concern in studies of people outranks animal and lab studies, and “No concerns” needs at least two findings in people. Findings whose study type is not stated are shown but not counted. This page is a reference, not medical advice. It describes what regulators and published research say. Talk to a doctor or dietitian about your own diet.
Products
The 6 most-scanned of 6,004 products on Open Food Facts that list cottonseed.
- Smooth Kraft · 2 kg 1 additive
- Peanut Butter SKIPPY · 16.3oz 0 additives
- Sour Cream & Onion Pringles 7 additives
- Creamy Peanut Butter SKIPPY · 1.36 kg 0 additives
- PEANUT BUTTER SKIPPY · 40 oz 0 additives
- CHEESED CHEESE NATURALLY FLAVORED PRINGLES · 5.5 oz (158 g) 8 additives
References
- 1cottonseed: ingredient taxonomy entry. Open Food Facts.
- 2Hart TL, Petersen KS, Kris-Etherton PM. The effect of cottonseed oil on lipids/lipoproteins: a systematic review and plasma cholesterol predictive equations estimations. Nutr Rev. 2024;82(8):1079-1086. doi:10.1093/nutrit/nuad109
- 3Prater MC, Scheurell AR, Paton CM, Cooper JA. Hunger and satiety responses to diets enriched with cottonseed oil vs. olive oil. Physiol Behav. 2023;259:114041. doi:10.1016/j.physbeh.2022.114041
- 4Riaz T, Iqbal MW, Mahmood S, et al. Cottonseed oil: A review of extraction techniques, physicochemical, functional, and nutritional properties. Crit Rev Food Sci Nutr. 2023;63(9):1219-1237. doi:10.1080/10408398.2021.1963206
- 5Zia MA, Shah SH, Shoukat S, Hussain Z, Khan SU, Shafqat N. Physicochemical features, functional characteristics, and health benefits of cottonseed oil: a review. Braz J Biol. 2021;82:e243511. doi:10.1590/1519-6984.243511
- 6Xu S, Yang R, Wei X, et al. A comprehensive review on cottonseed oil: Composition, processing, quality control, and biotechnological innovations. Food Chem. 2026;525(Pt 1):150348. doi:10.1016/j.foodchem.2026.150348
- 7Prater MC, Cooper JA. Is Cottonseed Oil the Next Healthy Oil? J Med Food. 2024;27(12):1141-1144. doi:10.1089/jmf.2024.0114
- 8Park JS, Choi J, Hwang SH, et al. Cottonseed Oil Protects Against Intestinal Inflammation in Dextran Sodium Sulfate-Induced Inflammatory Bowel Disease. J Med Food. 2019;22(7):672-679. doi:10.1089/jmf.2018.4323