Cyanocobalamin
What the research shows
PrototypeConflicting
studies in people disagree or haven’t settled it
2 health findings on this page · See the findings
A form of vitamin B12.
It treats and prevents vitamin B12 deficiency.
Written from English Wikipedia1
- Vegan
- Vegetarian
What research says
Studies in people
-
Benefit
Oral treatment for anemia2
In people with pernicious anemia, taking cyanocobalamin by mouth improved vitamin B12 levels within a month.
-
Concern
Skin bacteria and acne3
In one of ten people studied, vitamin B12 supplements changed skin bacteria and acne appeared.
Study type not stated
-
Benefit
low vitamin levels4
Vitamin B12 is needed for DNA and energy, and low levels are common in vegetarians and older people.
How it’s made and used
-
nutrient absorption at meals5
How much cyanocobalamin the body absorbs drops when you eat more of it in one meal.
The signal at the top counts the findings in people and in animal and lab studies. A concern in studies of people outranks animal and lab studies, and “No concerns” needs at least two findings in people. Findings whose study type is not stated are shown but not counted. This page is a reference, not medical advice. It describes what regulators and published research say. Talk to a doctor or dietitian about your own diet.
Products
The 6 most-scanned of 5,171 products on Open Food Facts that list cyanocobalamin.
- Nutritional Yeast Flakes Engevita · 100 g 0 additives
- Vanilla Huel · 1 Bottle 3 additives
- Chocolate Huel · 1 Bottle 3 additives
- Organic Unsweetened Almond Non-Dairy Beverage Vanilla Kirkland Signature · 946 ml 3 additives
- Soya Unsweetened plant based Lidl · 1000 ml 1 additive
- Vanilla Protein Shake Premier Protein · 11 ounces 7 additives
References
- 1Cyanocobalamin. Wikipedia. Accessed September 26, 2026.
- 2Lacombe V, Vinatier E, Roquin G, et al. Oral vitamin B12 supplementation in pernicious anemia: a prospective cohort study. Am J Clin Nutr. 2024;120(1):217-224. doi:10.1016/j.ajcnut.2024.05.019
- 3Kang D, Shi B, Erfe MC, Craft N, Li H. Vitamin B12 modulates the transcriptome of the skin microbiota in acne pathogenesis. Sci Transl Med. 2015;7(293):293ra103. doi:10.1126/scitranslmed.aab2009
- 4O'Leary F, Samman S. Vitamin B12 in health and disease. Nutrients. 2010;2(3):299-316. doi:10.3390/nu2030299
- 5Watanabe F. Vitamin B12 sources and bioavailability. Exp Biol Med (Maywood). 2007;232(10):1266-74. doi:10.3181/0703-MR-67