E620
Glutamic acid
What the research shows
No concerns
none of the findings here link it to harm
A building block of proteins that gives food a savory taste.
It adds a savory flavor to foods.1
- Vegan
- Vegetarian
- EU permitted
What research says
Studies in people
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No harm found
Eye damage from diabetes2
In people with type 2 diabetes, eating more glutamic acid did not change their risk of diabetic eye disease.
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Benefit
Colon cancer risk4
In older adults, eating more glutamic acid was linked to lower colorectal cancer risk, mainly in those not overweight.
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Benefit
Stroke risk in women5
In a Japanese study, women who ate more glutamic acid were less likely to die from stroke.
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Open question
Blood pressure7
In people, eating more glutamic acid was linked to slightly lower blood pressure.
How it’s made and used
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Infant formula intake3
Babies fed infant formula took in more glutamic acid than the recommended daily amount.
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Taste threshold for broth6
Untrained people could not tell chicken broth with added glutamic acid from plain broth, even at the highest amount tested.
The signal at the top counts the findings in people and in animal and lab studies. A concern in studies of people outranks animal and lab studies, and “No concerns” needs at least one finding in people. When most findings in people point one way, the page leans that way (“Mostly”), and every finding is still shown. Findings whose study type is not stated are shown but not counted. This page is a reference, not medical advice. It describes what regulators and published research say. Talk to a doctor or dietitian about your own diet.
Regulatory status
Checked Sep 2026-
United States Permitted FDA 21 CFR 182.1045
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European Union Permitted EUR-Lex Reg. (EC) 1333/2008
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United Kingdom Permitted FSA retained EU law
Status reflects the named register on the date checked. It is not a safety rating. A country appears here once we've found this ingredient on its official list.
How we checkProducts
The 6 most-scanned of 148 products on Open Food Facts that list glutamic acid.
- CHIK'N NUGGETS Morning Star FARMS 6 additives
- Ranch KEN'S Steak House 11 additives
- Ranch Dressing KEN'S Steak House 11 additives
- Original Chik'n Patties MorningStar Farms · 10 oz 6 additives
- ORIGINAL CHIK'N PATTIES MorningStar FARMS 6 additives
- Smart Dogs Plant-Based Hot Dogs Canada Lightlife · 340 g 5 additives
References
- 1Glutamic acid. Wikipedia. Accessed September 26, 2026. CC BY-SA 4.0.
- 2Park SY, Kim J, Son JI, et al. Dietary glutamic acid and aspartic acid as biomarkers for predicting diabetic retinopathy. Sci Rep. 2021;11(1):7244. doi:10.1038/s41598-021-83165-5
- 3Mennella JA, Smethers AD, Delahanty MT, Stallings VA, Trabulsi JC. Glutamic acid intake by formula-fed infants: are acceptable daily intakes appropriate? Eur J Pediatr. 2023;182(12):5701-5705. doi:10.1007/s00431-023-05215-6
- 4Viana Veloso GG, Franco OH, Ruiter R, et al. Baseline dietary glutamic acid intake and the risk of colorectal cancer: The Rotterdam study. Cancer. 2016;122(6):899-907. doi:10.1002/cncr.29862
- 5Nagata C, Wada K, Tamura T, et al. Dietary intakes of glutamic acid and glycine are associated with stroke mortality in Japanese adults. J Nutr. 2015;145(4):720-8. doi:10.3945/jn.114.201293
- 6Watanabe G, Ishida S, Akada K, et al. Discrimination thresholds for glutamic acid and chicken oil in chicken broth assessed by an untrained panel at a research institute. Anim Sci J. 2025;96(1):e70022. doi:10.1111/asj.70022
- 7Stamler J, Brown IJ, Daviglus ML, et al. Glutamic acid, the main dietary amino acid, and blood pressure: the INTERMAP Study (International Collaborative Study of Macronutrients, Micronutrients and Blood Pressure). Circulation. 2009;120(3):221-8. doi:10.1161/CIRCULATIONAHA.108.839241