Grana Padano

What the research shows

No concerns

none of the findings here link it to harm*

*Allergies present

A hard Italian cheese made from cows' milk.12

What research says

Studies in people

  • Benefit

    Blood pressure in adults3

    Eating a small daily serving of Grana Padano cheese lowered blood pressure in people with mild to moderate high blood pressure.

  • Open question

    Egg allergy and cheese5

    People with egg allergy ate Grana Padano cheese, and its lysozyme caused no reaction, though a few showed a small immune response.

Study type not stated

Allergies and intolerances

These are about people with an allergy, an intolerance or coeliac disease. The signal is about the ingredient itself, and these are about the person eating it, so the signal does not count them.

  • Egg allergy in children4

    Some children allergic to egg reacted to Grana Padano made with egg lysozyme, though cheese aged 24 months caused fewer reactions.

How it’s made and used

The signal at the top counts the findings in people and in animal and lab studies. A concern in studies of people outranks animal and lab studies, and “No concerns” needs at least one finding in people. When most findings in people point one way, the page leans that way (“Mostly”), and every finding is still shown. Findings whose study type is not stated are shown but not counted. This page is a reference, not medical advice. It describes what regulators and published research say. Talk to a doctor or dietitian about your own diet.

Products

The 6 most-scanned of 305 products on Open Food Facts that list grana padano.

  • Pesto Rosso BARILLA · 200 g 1 additive
  • Classic Pesto Filippo Berio · 190 g 1 additive
  • HEINZ TOMATO, GRANA PADANO & MASCARPONE PASTA SAUCE HEINZ · 350 g 0 additives
  • Pesto Sun-Dried Tomato Saclà · 190 g 2 additives
  • Green Pesto Tesco · 190 g 2 additives
  • Green Pesto Sauce sainsburys · 190 g 3 additives

References

  1. 1Grana Padano: ingredient taxonomy entry. Open Food Facts.
  2. 2Grana Padano. Wikipedia. Accessed September 30, 2026. CC BY-SA 4.0.
  3. 3Crippa G, Zabzuni D, Bravi E, et al. Randomized, double blind placebo-controlled pilot study of the antihypertensive effects of Grana Padano D.O.P. cheese consumption in mild - moderate hypertensive subjects. Eur Rev Med Pharmacol Sci. 2018;22(21):7573-7581. doi:10.26355/eurrev_201811_16299
  4. 4Marseglia A, Castellazzi AM, Valsecchi C, et al. Outcome of oral provocation test in egg-sensitive children receiving semi-fat hard cheese Grana Padano PDO (protected designation of origin) containing, or not, lysozyme. Eur J Nutr. 2013;52(3):877-83. doi:10.1007/s00394-012-0394-5
  5. 5Iaconelli A, Fiorentini L, Bruschi S, Rossi F, Mingrone G, Piva G. Absence of allergic reactions to egg white lysozyme additive in Grana Padano cheese. J Am Coll Nutr. 2008;27(2):326-31. doi:10.1080/07315724.2008.10719707
  6. 6Summer A, Formaggioni P, Franceschi P, Di Frangia F, Righi F, Malacarne M. Cheese as Functional Food: The Example of Parmigiano Reggiano and Grana Padano. Food Technol Biotechnol. 2017;55(3):277-289. doi:10.17113/ftb.55.03.17.5233
  7. 7Cammi G, Ricchi M, Galiero A, et al. Evaluation of Mycobacterium avium subsp. paratuberculosis survival during the manufacturing process of Italian raw milk hard cheeses (Parmigiano Reggiano and Grana Padano). Int J Food Microbiol. 2019;305:108247. doi:10.1016/j.ijfoodmicro.2019.108247