Isomaltulose

What the research shows

Mostly no concerns

most studies in people found no harm or a benefit

A sugar alternative made from table sugar.

It tastes like sugar but is digested slower, giving a lower blood glucose response.1

What research says

Studies in people

  • Benefit

    Blood sugar after meals2

    In people with diabetes, isomaltulose raised blood sugar less than sucrose an hour after eating.

  • Benefit

    Blood sugar control3

    Isomaltulose is a sugar that raises blood sugar less than regular sugar does.

  • Open question

    Blood sugar after eating4

    Isomaltulose is a sugar that raises blood sugar and insulin more slowly than regular sugar.

  • Benefit

    Blood vessel health5

    In people, isomaltulose kept blood vessels working better than sugar after a meal.

  • Benefit

    Weight loss and body fat6

    In overweight adults, isomaltulose in a reduced-calorie diet led to more weight and fat loss than sucrose.

  • Benefit

    Rehydration after exercise7

    In young men, a 6.5% isomaltulose-electrolyte drink after exercise in heat restored hydration better than water or a 2% drink.

  • Open question

    Appetite and blood sugar8

    In people, trifle sweetened with isomaltulose raised blood sugar less than sucrose, but hunger and later eating were the same.

  • Open question

    Blood sugar in babies9

    In infants fed formula with isomaltulose, blood sugar 60 minutes after feeding was higher than with regular formula.

  • Benefit

    Blood sugar and fat burning10

    In overweight men with insulin resistance, isomaltulose led to lower blood sugar and insulin and more fat burning than regular sugar.

  • Benefit

    Plaque on teeth11

    In people, isomaltulose snacks led to less plaque on teeth than sucrose snacks did.

  • Benefit

    Artery stiffness after eating13

    In middle-aged and older adults, isomaltulose kept arteries from stiffening after eating, unlike sucrose.

  • Benefit

    Blood sugar during exercise14

    In people with type 1 diabetes, isomaltulose before running kept blood sugar steadier than dextrose did.

  • Concern

    Stomach comfort during exercise15

    In male cyclists, isomaltulose caused worse stomach cramps and bloating and slower time-trial times than a fructose-maltodextrin drink.

  • Benefit

    Blood sugar control in diabetes16

    In people with type 2 diabetes, isomaltulose did not change blood sugar control but triglycerides were lower.

How it’s made and used

The signal at the top counts the findings in people and in animal and lab studies. A concern in studies of people outranks animal and lab studies, and “No concerns” needs at least one finding in people. When most findings in people point one way, the page leans that way (“Mostly”), and every finding is still shown. Findings whose study type is not stated are shown but not counted. This page is a reference, not medical advice. It describes what regulators and published research say. Talk to a doctor or dietitian about your own diet.

Products

The 6 most-scanned of 78 products on Open Food Facts that list isomaltulose.

  • Soft Bakes Choc Chip Belvita · 5x 7 additives
  • Soft Bakes Choc Chips belVita 6 additives
  • Soft Bakes Blueberry Belvita · 250 g 5 additives
  • Soft Bakes Choco Hazelnut Flavour belVita · 250 g 4 additives
  • Breakfast Biscuits Soft Bakes Filled Choco Hazelnut Belvita · 250 g 5 additives
  • Soft Bakes Blueberry Crownfield · 250 g 6 additives

References

  1. 1Isomaltulose. Wikipedia. Accessed September 30, 2026. CC BY-SA 4.0.
  2. 2Chen Z, Gu F, Wu J. Impact of Isomaltulose on Glycemic Response in Diabetic and Healthy Populations: A Meta-Analysis. Nutrients. 2025;17(11). doi:10.3390/nu17111940
  3. 3Maresch CC, Petry SF, Theis S, Bosy-Westphal A, Linn T. Low Glycemic Index Prototype Isomaltulose-Update of Clinical Trials. Nutrients. 2017;9(4). doi:10.3390/nu9040381
  4. 4Lina BA, Jonker D, Kozianowski G. Isomaltulose (Palatinose): a review of biological and toxicological studies. Food Chem Toxicol. 2002;40(10):1375-81. doi:10.1016/s0278-6915(02)00105-9
  5. 5de Groot E, Schweitzer L, Theis S. Efficacy of Isomaltulose Compared to Sucrose in Modulating Endothelial Function in Overweight Adults. Nutrients. 2020;12(1). doi:10.3390/nu12010141
  6. 6Lightowler H, Schweitzer L, Theis S, Henry CJ. Changes in Weight and Substrate Oxidation in Overweight Adults Following Isomaltulose Intake During a 12-Week Weight Loss Intervention: A Randomized, Double-Blind, Controlled Trial. Nutrients. 2019;11(10). doi:10.3390/nu11102367
  7. 7Amano T, Sugiyama Y, Okumura J, et al. Effects of isomaltulose ingestion on postexercise hydration state and heat loss responses in young men. Exp Physiol. 2019;104(10):1494-1504. doi:10.1113/EP087843
  8. 8Kendall FE, Marchand O, Haszard JJ, Venn BJ. The Comparative Effect on Satiety and Subsequent Energy Intake of Ingesting Sucrose or Isomaltulose Sweetened Trifle: A Randomized Crossover Trial. Nutrients. 2018;10(10). doi:10.3390/nu10101504
  9. 9Fleddermann M, Rauh-Pfeiffer A, Demmelmair H, Holdt L, Teupser D, Koletzko B. Effects of a Follow-On Formula Containing Isomaltulose (Palatinose™) on Metabolic Response, Acceptance, Tolerance and Safety in Infants: A Randomized-Controlled Trial. PLoS One. 2016;11(3):e0151614. doi:10.1371/journal.pone.0151614
  10. 10König D, Theis S, Kozianowski G, Berg A. Postprandial substrate use in overweight subjects with the metabolic syndrome after isomaltulose (Palatinose™) ingestion. Nutrition. 2012;28(6):651-6. doi:10.1016/j.nut.2011.09.019
  11. 11Ooshima T, Izumitani A, Takei T, Fujiwara T, Sobue S. Plaque formation of dietary isomaltulose in humans. Caries Res. 1990;24(1):48-51. doi:10.1159/000261238
  12. 12Amano T, Watanabe D, Otsuka J, et al. Comparison of hydration efficacy of carbohydrate-electrolytes beverages consisting of isomaltulose and sucrose in healthy young adults: A randomized crossover trial. Physiol Behav. 2022;249:113770. doi:10.1016/j.physbeh.2022.113770
  13. 13Kobayashi R, Sakazaki M, Nagai Y, Asaki K, Hashiguchi T, Negoro H. Effects of Different Types of Carbohydrates on Arterial Stiffness: A Comparison of Isomaltulose and Sucrose. Nutrients. 2021;13(12). doi:10.3390/nu13124493
  14. 14West DJ, Morton RD, Stephens JW, et al. Isomaltulose Improves Postexercise Glycemia by Reducing CHO Oxidation in T1DM. Med Sci Sports Exerc. 2011;43(2):204-10. doi:10.1249/MSS.0b013e3181eb6147
  15. 15Oosthuyse T, Carstens M, Millen AM. Ingesting Isomaltulose Versus Fructose-Maltodextrin During Prolonged Moderate-Heavy Exercise Increases Fat Oxidation but Impairs Gastrointestinal Comfort and Cycling Performance. Int J Sport Nutr Exerc Metab. 2015;25(5):427-38. doi:10.1123/ijsnem.2014-0178
  16. 16Brunner S, Holub I, Theis S, et al. Metabolic effects of replacing sucrose by isomaltulose in subjects with type 2 diabetes: a randomized double-blind trial. Diabetes Care. 2012;35(6):1249-51. doi:10.2337/dc11-1485