E161bColour
Lutein
What the research shows
Mostly no concerns
most studies in people found no harm or a benefit
Used in food as a colour.
- Vegan
- Vegetarian
- EU permitted
What research says
Studies in people
-
Benefit
Eye disease progression1
Lutein and zeaxanthin supplements may slow worsening of age-related macular degeneration, though scientists are still studying how much they help.
-
Benefit
Eye health and vision2
Lutein from food or supplements is widely recommended for eye health, but the science behind that advice is often overlooked.
-
No harm found
Vision loss in older adults3
In people at risk of vision loss, lutein plus zeaxanthin did not further lower the chance of the disease getting worse.
-
Benefit
Heart artery health4
In people, lutein with two related carotenoids lowered blood markers of inflammation and oxidized fats tied to artery plaque.
-
No harm found
Lung cancer risk5
In people with AMD, lutein/zeaxanthin showed no big lung cancer risk, unlike beta carotene.
-
Benefit
Children's eye and brain health6
In children given lutein and zeaxanthin gummies for 180 days, eye strain, focus and memory improved compared with placebo.
-
Benefit
Dry eye symptoms7
People taking lutein with zeaxanthin and elderberry for 20 days reported less dry eye discomfort.
-
Benefit
Eye and heart health8
Eating lutein from greens is linked to lower risk of eye and heart problems.
-
Benefit
Memory and thinking in adults9
In adults, lutein with zeaxanthin supplements were linked to better thinking, possibly by helping eyesight.
-
Benefit
Eye-hand coordination10
In people who work at screens, lutein with astaxanthin and zeaxanthin improved eye-hand coordination after eight weeks.
-
Benefit
Children's eye health12
In children, lutein ester supplements for six months slowed thinning of a layer inside the eye.
-
Concern
Lung function in smokers13
In smokers, eating more lutein was linked to worse lung function, but no link was seen overall.
-
Benefit
Eye blood flow14
In healthy women, lutein with other plant compounds increased blood flow in the eye's retina.
Animal and lab studies only
-
Benefit
Weight gain and belly fat20
In animal studies, lutein lowered belly fat, cholesterol and blood sugar in mice fed a high-fat diet.
Study type not stated
-
Benefit
Eye health15
Lutein is found in the eye and may help delay eye diseases, but scientists do not yet know the best dose.
-
Benefit
Antioxidant roles in plants16
In plants and humans, lutein and zeaxanthin have several protective roles, the review says.
-
Benefit
Eye and brain health17
Lutein, found in leafy greens and eggs, may help with eye and brain problems, but scientists do not yet know for sure.
-
Benefit
Infant brain and eye development18
Lutein may help a baby's eyes and brain grow, but scientists do not yet know for sure.
-
Benefit
Eye health and ageing19
Lutein builds up in the eye and may help protect against age-related macular degeneration.
How it’s made and used
-
Diet tracking accuracy11
In adults, a food questionnaire did not accurately measure lutein eaten from foods like spinach.
-
How much the body absorbs21
In lab studies, lutein in a liquid meal dropped by about 40% during one stage of digestion.
The signal at the top counts the findings in people and in animal and lab studies. A concern in studies of people outranks animal and lab studies, and “No concerns” needs at least one finding in people. When most findings in people point one way, the page leans that way (“Mostly”), and every finding is still shown. Findings whose study type is not stated are shown but not counted. This page is a reference, not medical advice. It describes what regulators and published research say. Talk to a doctor or dietitian about your own diet.
What expert reviews concluded
Expert panels that weigh all the research. Shown for context: the signal at the top does not count them.
-
UN and WHO food additive experts (JECFA), 1977
No acceptable daily intake set.
Regulatory status
Checked Sep 2026-
European Union Permitted EUR-Lex Reg. (EC) 1333/2008
-
United Kingdom Permitted FSA retained EU law
-
Canada Permitted Health Canada · Colouring Agents
Status reflects the named register on the date checked. It is not a safety rating. A country appears here once we've found this ingredient on its official list.
How we checkProducts
The 6 most-scanned of 607 products on Open Food Facts that list lutein.
- Bourn Vita 500Gram Pauch Cadbury 10 additives
- Banana Lunchbox Loaves Soreen 4 additives
- wine gums Maynards 9 additives
- Lemon curd Sainsbury's · 411 g 4 additives
- Jelly Babies Maynards Bassetts · 165 g 7 additives
- Korma Cooking Sauce Sharwood's · 420 g 3 additives
References
- 1Mrowicka M, Mrowicki J, Kucharska E, Majsterek I. Lutein and Zeaxanthin and Their Roles in Age-Related Macular Degeneration-Neurodegenerative Disease. Nutrients. 2022;14(4). doi:10.3390/nu14040827
- 2Bernstein PS, Li B, Vachali PP, et al. Lutein, zeaxanthin, and meso-zeaxanthin: The basic and clinical science underlying carotenoid-based nutritional interventions against ocular disease. Prog Retin Eye Res. 2016;50:34-66. doi:10.1016/j.preteyeres.2015.10.003
- 3Age-Related Eye Disease Study 2 Research Group. Lutein + zeaxanthin and omega-3 fatty acids for age-related macular degeneration: the Age-Related Eye Disease Study 2 (AREDS2) randomized clinical trial. JAMA. 2013;309(19):2005-15. doi:10.1001/jama.2013.4997
- 4Stringham NT, Green M, Roche W, Prado-Cabrero A, Mulcahy R, Nolan J. Lutein, zeaxanthin, and meso-zeaxanthin supplementation attenuates inflammatory cytokines and markers of oxidative cardiovascular processes in humans. Nutr Metab Cardiovasc Dis. 2024;34(8):1976-1983. doi:10.1016/j.numecd.2024.05.009
- 5Chew EY, Clemons TE, Agrón E, et al. Long-term Outcomes of Adding Lutein/Zeaxanthin and ω-3 Fatty Acids to the AREDS Supplements on Age-Related Macular Degeneration Progression: AREDS2 Report 28. JAMA Ophthalmol. 2022;140(7):692-698. doi:10.1001/jamaophthalmol.2022.1640
- 6Parekh R, Hammond BR Jr, Chandradhara D. Lutein and Zeaxanthin Supplementation Improves Dynamic Visual and Cognitive Performance in Children: A Randomized, Double-Blind, Parallel, Placebo-Controlled Study. Adv Ther. 2024;41(4):1496-1511. doi:10.1007/s12325-024-02785-1
- 7Goh KM, Tan ESS, Lim CSY, et al. Effect of Dietary Supplementation with Lutein, Zeaxanthin, and Elderberries on Dry Eye Disease (DED) and Immunity: A Randomized Controlled Trial. Nutrients. 2024;16(24). doi:10.3390/nu16244366
- 8Li N, Wu X, Zhuang W, et al. Green leafy vegetable and lutein intake and multiple health outcomes. Food Chem. 2021;360:130145. doi:10.1016/j.foodchem.2021.130145
- 9Wang H, Wang G, Billings R, et al. Can Diet Supplements of Macular Pigment of Lutein, Zeaxanthin, and Meso-zeaxanthin Affect Cognition? J Alzheimers Dis. 2022;87(3):1079-1087. doi:10.3233/JAD-215736
- 10Yoshida K, Sakai O, Honda T, et al. Effects of Astaxanthin, Lutein, and Zeaxanthin on Eye-Hand Coordination and Smooth-Pursuit Eye Movement after Visual Display Terminal Operation in Healthy Subjects: A Randomized, Double-Blind Placebo-Controlled Intergroup Trial. Nutrients. 2023;15(6). doi:10.3390/nu15061459
- 11Fitzpatrick NK, Capra S, Shore A, et al. Newly developed dietary assessment tools for lutein and zeaxanthin are correlated with 24-hour diet recalls, but are not a valid measure of intake in Australian and United Kingdom adults. Nutr Res. 2024;122:68-79. doi:10.1016/j.nutres.2023.12.010
- 12Li T, Li J, Deng C, et al. Effect of Lutein Ester Supplement on Choroidal Thickness in Children: A Randomized Controlled Trial. Transl Vis Sci Technol. 2025;14(12):7. doi:10.1167/tvst.14.12.7
- 13Melo van Lent D, Leermakers ET, Hofman A, et al. Association between lutein intake and lung function in adults: the Rotterdam Study. Br J Nutr. 2017;117(5):720-730. doi:10.1017/S0007114517000319
- 14Harris A, Siesky B, Huang A, et al. Lutein Complex Supplementation Increases Ocular Blood Flow Biomarkers in Healthy Subjects. Int J Vitam Nutr Res. 2019;89(1-2):5-12. doi:10.1024/0300-9831/a000576
- 15Li LH, Lee JC, Leung HH, Lam WC, Fu Z, Lo ACY. Lutein Supplementation for Eye Diseases. Nutrients. 2020;12(6). doi:10.3390/nu12061721
- 16Demmig-Adams B, López-Pozo M, Stewart JJ, Adams WW 3rd. Zeaxanthin and Lutein: Photoprotectors, Anti-Inflammatories, and Brain Food. Molecules. 2020;25(16). doi:10.3390/molecules25163607
- 17Mitra S, Rauf A, Tareq AM, et al. Potential health benefits of carotenoid lutein: An updated review. Food Chem Toxicol. 2021;154:112328. doi:10.1016/j.fct.2021.112328
- 18Giordano E, Quadro L. Lutein, zeaxanthin and mammalian development: Metabolism, functions and implications for health. Arch Biochem Biophys. 2018;647:33-40. doi:10.1016/j.abb.2018.04.008
- 19Fiedorowicz J, Dobrzynska MM. Lutein and zeaxanthin - radio- and chemoprotective properties. Mechanism and possible use. Rocz Panstw Zakl Hig. 2023;74(3):257-264. doi:10.32394/rpzh.2023.0266
- 20Gopal SS, Sukhdeo SV, Vallikannan B, Ponesakki G. Lutein ameliorates high-fat diet-induced obesity, fatty liver, and glucose intolerance in C57BL/6J mice. Phytother Res. 2023;37(1):329-341. doi:10.1002/ptr.7615
- 21Kopec RE, Gleize B, Borel P, Desmarchelier C, Caris-Veyrat C. Are lutein, lycopene, and β-carotene lost through the digestive process? Food Funct. 2017;8(4):1494-1503. doi:10.1039/c7fo00021a