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Magnesium oxide
What the research shows
PrototypeNo concerns
none of the findings here link it to harm
3 health findings on this page, all in people · See the findings
A white mineral that is a source of magnesium.
Written from English Wikipedia1
- Vegan
- Vegetarian
- EU permitted
What research says
Studies in people
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Benefit
Night leg cramps2
In people, magnesium oxide monohydrate reduced how often and how long night leg cramps happened, and improved sleep.
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Benefit
Kidney stone risk3
In people, magnesium oxide lowered oxalate in urine, which matters for kidney stones, though less than magnesium citrate did.
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Benefit
Bone strength in girls4
In girls, taking magnesium oxide daily led to more bone buildup in the hip.
Study type not stated
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Open question
Artery stiffness5
Scientists do not yet know whether magnesium oxide affects artery stiffness, blood pressure or gut bacteria in people.
The signal at the top counts the findings in people and in animal and lab studies. A concern in studies of people outranks animal and lab studies, and “No concerns” needs at least two findings in people. Findings whose study type is not stated are shown but not counted. This page is a reference, not medical advice. It describes what regulators and published research say. Talk to a doctor or dietitian about your own diet.
Regulatory status
Checked Sep 2026-
United States Permitted FDA 21 CFR 184.1431
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European Union Permitted EUR-Lex Reg. (EC) 1333/2008
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United Kingdom Permitted FSA retained EU law
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Canada Permitted Health Canada · Anticaking Agents
Status reflects the named register on the date checked. It is not a safety rating.
How we checkProducts
The 6 most-scanned of 2,156 products on Open Food Facts that list magnesium oxide.
- Purified Drinking Water Kirkland Signature · 500 mL 2 additives
- Kirkland Spring Water 500ml Kirkland Signature · 500 ml 2 additives
- MuscleTech, Platinum Multivitamin Muscletech · 90 tablets 1 additive
- Purified water Kirkland Signature 2 additives
- Protein Powder Drink Mix Isopure · 30.5 g 3 additives
- Vector Kellogg's · 400 g 3 additives
References
- 1Magnesium oxide. Wikipedia. Accessed September 26, 2026.
- 2Barna O, Lohoida P, Holovchenko Y, et al. A randomized, double-blind, placebo-controlled, multicenter study assessing the efficacy of magnesium oxide monohydrate in the treatment of nocturnal leg cramps. Nutr J. 2021;20(1):90. doi:10.1186/s12937-021-00747-9
- 3Taheri M, Jalali S, Borumandnia N, Tavasoli S, Basiri A, Taheri F. Effect of magnesium oxide or citrate supplements on metabolic risk factors in kidney stone formers with idiopathic hyperoxaluria: a randomized clinical trial. Magnes Res. 2024;37(1):12-21. doi:10.1684/mrh.2024.0524
- 4Carpenter TO, DeLucia MC, Zhang JH, et al. A randomized controlled study of effects of dietary magnesium oxide supplementation on bone mineral content in healthy girls. J Clin Endocrinol Metab. 2006;91(12):4866-72. doi:10.1210/jc.2006-1391
- 5Schutten JC, Joris PJ, Mensink RP, et al. Effects of magnesium citrate, magnesium oxide and magnesium sulfate supplementation on arterial stiffness in healthy overweight individuals: a study protocol for a randomized controlled trial. Trials. 2019;20(1):295. doi:10.1186/s13063-019-3414-4