Maltodextrin
What the research shows
Mostly no concerns
most studies in people found no harm or a benefit
A white solid made from plant starches.
It is digested fast and gives the body glucose for energy.1
- Vegan
- Vegetarian
What research says
Studies in people
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Concern
Gut bacteria changes2
In studies of people, maltodextrin often changed gut bacteria and immune markers, so scientists question whether it truly works as a placebo.
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Open question
Bowel movements3
Resistant maltodextrin, a fiber, made stool volume and frequency go up in people who took it.
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Benefit
Gut bacteria balance7
In people, maltodextrin used as a placebo helped gut bifidobacteria grow, so it may act like a prebiotic.
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Benefit
Blood sugar control8
In 17 healthy adults, a drink with 30% tapioca resistant maltodextrin lowered insulin after meals.
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Benefit
Post-run inflammation9
In runners, maltodextrin-fructose taken around a hard run lowered signs of inflammation afterward.
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No harm found
Tooth decay10
In people, maltodextrin mixed with sugar did not change how much the sugar caused tooth decay.
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Benefit
Appetite and fullness11
In men, a soup with maltodextrin before lunch left them less hungry and they ate less.
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No harm found
Newborn feeding13
Newborns given maltodextrin when breast milk ran short did as well as those given formula.
Animal and lab studies only
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Concern
Gut inflammation15
In lab studies, maltodextrin weakened cells' ability to fight bacteria and their gut defenses.
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Benefit
Colon cancer growth16
In lab and animal studies, maltodextrin (Fibersol-2) slowed colon cancer cell growth, but it is not known if this happens in people.
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Concern
Gut inflammation in mice17
In mice, maltodextrin made colitis worse and cut the mucus that protects the gut lining.
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Open question
Diarrhea germ toxin growth18
In baby formula containing maltodextrin, a germ that causes diarrhea grew and made toxin.
How it’s made and used
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Muscle fuel during exercise4
In people, taking maltodextrin before leg press exercise did not improve how many reps they could do.
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Stomach emptying in labour5
In labouring women, maltodextrin left the stomach faster than coffee with milk or orange juice.
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Fiber and fish oil effects6
In older adults, maltodextrin plus corn oil differed from fish oil plus fiber in gut bacteria and cell pathways.
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Endurance during recovery12
In athletes, taking maltodextrin with fructose during recovery let them run longer afterward than maltodextrin with glucose.
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Cheese texture and taste14
Adding maltodextrin to low-fat soft cheese made it creamier and smoother, though too much gave a starchy taste.
The signal at the top counts the findings in people and in animal and lab studies. A concern in studies of people outranks animal and lab studies, and “No concerns” needs at least one finding in people. When most findings in people point one way, the page leans that way (“Mostly”), and every finding is still shown. Findings whose study type is not stated are shown but not counted. This page is a reference, not medical advice. It describes what regulators and published research say. Talk to a doctor or dietitian about your own diet.
Products
The 6 most-scanned of 41,429 products on Open Food Facts that list maltodextrin.
- Croissance réduit en sucre Jaouda · 500 ml 1 additive
- Paprika Pringles · 165 g 6 additives
- Protein Nut Bar Fruit & Chocolate Nature Valley · 160 g 4 additives
- Pringles Original Pringles · 40 g 2 additives
- Pringles Original Pringles · 165 g 1 additive
- Pringles sour cream & onion Pringles · 40 g 8 additives
References
- 1Maltodextrin. Wikipedia. Accessed September 26, 2026. CC BY-SA 4.0.
- 2Almutairi R, Basson AR, Wearsh P, Cominelli F, Rodriguez-Palacios A. Validity of food additive maltodextrin as placebo and effects on human gut physiology: systematic review of placebo-controlled clinical trials. Eur J Nutr. 2022;61(6):2853-2871. doi:10.1007/s00394-022-02802-5
- 3Watanabe N, Suzuki M, Yamaguchi Y, Egashira Y. Effects of resistant maltodextrin on bowel movements: a systematic review and meta-analysis. Clin Exp Gastroenterol. 2018;11:85-96. doi:10.2147/CEG.S153924
- 4Wilburn DT, Machek SB, Cardaci TD, Hwang PS, Willoughby DS. Acute Maltodextrin Supplementation During Resistance Exercise. J Sports Sci Med. 2020;19(2):282-288.
- 5Nascimento AC, Goveia CS, Guimarães GMN, Filho RPL, Ladeira LCA, Silva HBG. Assessment of gastric emptying of maltodextrin, coffee with milk and orange juice during labour at term using point of care ultrasound: a non-inferiority randomised clinical trial. Anaesthesia. 2019;74(7):856-861. doi:10.1111/anae.14671
- 6Moosavi D, Mullens DA, Davidson LA, et al. Gut microbial community and host intestinal gene expression with combined fish oil and soluble corn fiber compared with corn oil and maltodextrin: A randomized crossover trial in healthy older individuals. Am J Clin Nutr. 2025;122(2):396-412. doi:10.1016/j.ajcnut.2025.04.031
- 7Calgaro M, Pandolfo M, Salvetti E, et al. Metabarcoding analysis of gut microbiota of healthy individuals reveals impact of probiotic and maltodextrin consumption. Benef Microbes. 2021;12(2):121-136. doi:10.3920/BM2020.0137
- 8Astina J, Saphyakhajorn W, Borompichaichartkul C, Sapwarobol S. Tapioca Resistant Maltodextrin as a Carbohydrate Source of Oral Nutrition Supplement (ONS) on Metabolic Indicators: A Clinical Trial. Nutrients. 2022;14(5). doi:10.3390/nu14050916
- 9Righetti S, Medoro A, Graziano F, et al. Effects of Maltodextrin-Fructose Supplementation on Inflammatory Biomarkers and Lipidomic Profile Following Endurance Running: A Randomized Placebo-Controlled Cross-Over Trial. Nutrients. 2024;16(18). doi:10.3390/nu16183078
- 10Rezende G, Arthur RA, Grando D, Hashizume LN. Cariogenic Potential of Sucrose Associated with Maltodextrin on Dental Enamel. Caries Res. 2017;51(2):129-135. doi:10.1159/000453623
- 11Yeomans MR, Gray RW, Conyers TH. Maltodextrin preloads reduce food intake without altering the appetiser effect. Physiol Behav. 1998;64(4):501-6. doi:10.1016/s0031-9384(98)00086-9
- 12Maunder E, Podlogar T, Wallis GA. Postexercise Fructose-Maltodextrin Ingestion Enhances Subsequent Endurance Capacity. Med Sci Sports Exerc. 2018;50(5):1039-1045. doi:10.1249/MSS.0000000000001516
- 13Rosegger H. [Maltodextrin in a 13% solution as a supplement in the first 4 days of life in breast-fed mature newborn infants. Effect on drinking behavior, weight curve, blood picture, blood glucose and bilirubin]. Wien Klin Wochenschr. 1986;98(10):310-5.
- 14Iakovchenko NV, Arseneva TP. Tapioca maltodextrin in the production of soft unripened cheese. Acta Sci Pol Technol Aliment. 2016;15(1):47-56. doi:10.17306/J.AFS.2016.1.5
- 15Nickerson KP, Chanin R, McDonald C. Deregulation of intestinal anti-microbial defense by the dietary additive, maltodextrin. Gut Microbes. 2015;6(1):78-83. doi:10.1080/19490976.2015.1005477
- 16So EY, Ouchi M, Cuesta-Sancho S, et al. Tumor suppression by resistant maltodextrin, Fibersol-2. Cancer Biol Ther. 2015;16(3):460-5. doi:10.1080/15384047.2015.1009269
- 17Zangara MT, Ponti AK, Miller ND, et al. Maltodextrin Consumption Impairs the Intestinal Mucus Barrier and Accelerates Colitis Through Direct Actions on the Epithelium. Front Immunol. 2022;13:841188. doi:10.3389/fimmu.2022.841188
- 18Rowan NJ, Anderson JG. Maltodextrin stimulates growth of Bacillus cereus and synthesis of diarrheal enterotoxin in infant milk formulae. Appl Environ Microbiol. 1997;63(3):1182-4. doi:10.1128/aem.63.3.1182-1184.1997