E461Emulsifier · Stabiliser · Thickener
Methyl cellulose
What the research shows
Concerning
in animal and lab studies only
What research says
Studies in people
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Benefit
Blood sugar after meals3
Methylcellulose eaten with breakfast lowered insulin levels in overweight adults, though it did not clearly lower blood sugar.
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Open question
Gut and bowel effects4
People who ate methyl cellulose for 23 days had bulkier stools, and no allergic or other bad effects were reported.
Animal and lab studies only
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Concern
Gut and tissue effects5
Methyl cellulose caused no tissue changes in rats, though very high amounts slowed their growth.
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Benefit
Edible coating during frying7
Coating fried dough cakes with methyl cellulose before frying cut the oil and harmful chemicals like acrylamide.
How it’s made and used
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Fat digestion6
In lab studies, methylcellulose added to emulsions slowed how much fat broke down during digestion.
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Oil absorbed by fried food8
A methylcellulose coating on fried potato chips cut the oil they soaked up by about a third.
The signal at the top counts the findings in people and in animal and lab studies. A concern in studies of people outranks animal and lab studies, and “No concerns” needs at least one finding in people. When most findings in people point one way, the page leans that way (“Mostly”), and every finding is still shown. Findings whose study type is not stated are shown but not counted. This page is a reference, not medical advice. It describes what regulators and published research say. Talk to a doctor or dietitian about your own diet.
What expert reviews concluded
Expert panels that weigh all the research. Shown for context: the signal at the top does not count them.
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UN and WHO food additive experts (JECFA), 1989
No daily limit needed (“ADI not specified”, JECFA’s term for very low toxicity).
Regulatory status
Checked Sep 2026-
United States Permitted FDA 21 CFR 182.1480
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European Union Permitted EUR-Lex Reg. (EC) 1333/2008
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United Kingdom Permitted FSA retained EU law
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Canada Permitted Health Canada · Emulsifying Gelling Stabilizing Thickening Agents
Status reflects the named register on the date checked. It is not a safety rating.
How we checkProducts
The 6 most-scanned of 2,217 products on Open Food Facts that list methyl cellulose.
- MEAT-FREE TASTY SAUSAGES RICHMOND · 304 g 3 additives
- Beyond Burger Beyond Meat · 226 g 3 additives
- 6 sausages vegan Linda McCartney · 270 g 4 additives
- Lincolnshire sausages Cauldron · 276 g 4 additives
- This isn't pork sausages This · 270 g 6 additives
- mozzarella 1/4lb burgers Linda McCartney · 227 g, 2 burgers 1 additive
References
- 1methyl cellulose: ingredient taxonomy entry. Open Food Facts.
- 2Methyl cellulose. Wikipedia. Accessed September 26, 2026. CC BY-SA 4.0.
- 3Maki KC, Carson ML, Miller MP, et al. Hydroxypropylmethylcellulose and methylcellulose consumption reduce postprandial insulinemia in overweight and obese men and women. J Nutr. 2008;138(2):292-6. doi:10.1093/jn/138.2.292
- 4Eastwood MA, Brydon WG, Anderson DM. The effects of dietary methylcellulose in man. Food Addit Contam. 1990;7(1):9-19. doi:10.1080/02652039009373814
- 5Younes M, Aggett P, Aguilar F, et al. Re-evaluation of celluloses E 460(i), E 460(ii), E 461, E 462, E 463, E 464, E 465, E 466, E 468 and E 469 as food additives. EFSA J. 2018;16(1):e05047. doi:10.2903/j.efsa.2018.5047
- 6Zhang L, Halket J, Caldwell A, Vllasaliu D, Bajka B, Dreiss CA. Controlling in vitro lipid digestion: Pickering emulsions with cellulose nanocrystals, chitosan and methylcellulose. Food Res Int. 2025;218:116793. doi:10.1016/j.foodres.2025.116793
- 7Han L, He YE, Wang S, et al. Effects of Methyl Cellulose and Soybean Protein Isolate Coating on Amount of Oil and Chemical Hazards in Chinese Fried Dough Cake. J Food Prot. 2021;84(8):1333-1339. doi:10.4315/JFP-21-062
- 8Tavera-Quiroz MJ, Urriza M, Pinotti A, Bertola N. Plasticized methylcellulose coating for reducing oil uptake in potato chips. J Sci Food Agric. 2012;92(7):1346-53. doi:10.1002/jsfa.4704