E961Sweetener
Neotame
What the research shows
Unclear
the research on this page hasn’t settled it
A sweetener that has no calories.
It makes food sweet and boosts other flavours.1
- Vegan
- Vegetarian
- EU permitted
What research says
Studies in people
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Open question
Appetite and blood sugar2
In adults with overweight or obesity, biscuits with Neotame reduced insulin after eating, but appetite was similar to sugar.
The signal at the top counts the findings in people and in animal and lab studies. A concern in studies of people outranks animal and lab studies, and “No concerns” needs at least one finding in people. When most findings in people point one way, the page leans that way (“Mostly”), and every finding is still shown. Findings whose study type is not stated are shown but not counted. This page is a reference, not medical advice. It describes what regulators and published research say. Talk to a doctor or dietitian about your own diet.
What expert reviews concluded
Expert panels that weigh all the research. Shown for context: the signal at the top does not count them.
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UN and WHO food additive experts (JECFA), 2003
Acceptable daily intake: up to 2 mg per kg of body weight.
Regulatory status
Checked Sep 2026-
United States Permitted FDA 21 CFR 172.829
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European Union Permitted EUR-Lex Reg. (EC) 1333/2008
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United Kingdom Permitted FSA retained EU law
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Canada Permitted Health Canada · Sweeteners
Status reflects the named register on the date checked. It is not a safety rating.
How we checkProducts
The 6 most-scanned of 235 products on Open Food Facts that list neotame.
- Tangy Original SunnyD 10 additives
- Ice breaker ice cubes peppermint Ice Breakers 15 additives
- Ice Breakers Ice Cubes Arctic Grape Sugar Free Gum Icebreakers 16 additives
- Thinck! Delight think! 9 additives
- Sunny D Tangy Original Sunny D · 8 oz 10 additives
- Ice Breakers IceCubes Spearmint Ice Breakers 13 additives
References
- 1Neotame. Wikipedia. Accessed September 26, 2026. CC BY-SA 4.0.
- 2Gibbons C, Beaulieu K, Almiron-Roig E, et al. Acute and two-week effects of neotame, stevia rebaudioside M and sucrose-sweetened biscuits on postprandial appetite and endocrine response in adults with overweight/obesity-a randomised crossover trial from the SWEET consortium. EBioMedicine. 2024;102:105005. doi:10.1016/j.ebiom.2024.105005