E375

Nicotinic acid

What the research shows

Prototype

No concerns

none of the findings here link it to harm

3 health findings on this page, all in people · See the findings

A form of vitamin B3.

It is an essential nutrient the body needs.

Written from English Wikipedia1

  • May not be vegan
  • May not be vegetarian

What research says

Studies in people

  • Benefit

    Fatty liver disease2

    People who ate more niacin in food were less likely to have fatty liver disease.

  • Benefit

    Eye health in diabetes3

    Eating more niacin was linked to fewer cases of diabetic eye disease, but we do not know if niacin causes this.

  • Benefit

    Suicidal thoughts4

    People who ate more niacin were less likely to report suicidal thoughts, though scientists do not yet know whether niacin causes this.

Study type not stated

  • Benefit

    How cells make energy5

    Nicotinic acid helps the body make NAD, which cells need for metabolism and respiration.

The signal at the top counts the findings in people and in animal and lab studies. A concern in studies of people outranks animal and lab studies, and “No concerns” needs at least two findings in people. Findings whose study type is not stated are shown but not counted. This page is a reference, not medical advice. It describes what regulators and published research say. Talk to a doctor or dietitian about your own diet.

Products

The 6 most-scanned of 74,072 products on Open Food Facts that list nicotinic acid.

  • Sésame Gerblé · 230 g 4 additives
  • Weetabix Weetabix · 430 g 0 additives
  • CORN FLAKES Kellogg's · 500 g 0 additives
  • Sablés Anglais L'Original McVitie's · 400 g 3 additives
  • Marmite Yeast Extract Marmite · 250 g 0 additives
  • Croissance réduit en sucre Jaouda · 500 ml 1 additive

References

  1. 1Nicotinic acid. Wikipedia. Accessed September 25, 2026.
  2. 2Pan J, Hu Y, Pang N, Yang L. Association between Dietary Niacin Intake and Nonalcoholic Fatty Liver Disease: NHANES 2003-2018. Nutrients. 2023;15(19). doi:10.3390/nu15194128
  3. 3Wang S, Li X, Chen M. Association of dietary niacin intake with diabetic retinopathy: A cross-sectional study. Medicine (Baltimore). 2025;104(47):e46064. doi:10.1097/MD.0000000000046064
  4. 4Lin H, Xu J, Wang B, Ye W, Jiang X, Qu S. Association between dietary niacin intake and suicidal ideation: mediating role of C-reactive protein. BMC Psychiatry. 2025;25(1):820. doi:10.1186/s12888-025-07278-1
  5. 5Kirkland JB, Meyer-Ficca ML. Niacin. Adv Food Nutr Res. 2018;83:83-149. doi:10.1016/bs.afnr.2017.11.003