E234Preservative
Nisin
A germ-killing substance made by a bacterium.
It is used as a preservative to keep food from spoiling.
Written from English Wikipedia1
- Vegan
- Vegetarian
- EU permitted
What research says
Study type not stated
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Open question
Gut bacteria health2
Scientists are exploring whether nisin, a food preservative, can change the bacteria living in your gut.
How it’s made and used
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Food preservatives3
Nisin has been used as a preservative in food, and researchers are still studying how it is made and used.
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germ-fighting power in meat4
Nisin loses its germ-fighting power faster in raw meat than in cooked meat, and scientists now know why.
The signal at the top counts the findings in people and in animal and lab studies. A concern in studies of people outranks animal and lab studies, and “No concerns” needs at least two findings in people. Findings whose study type is not stated are shown but not counted. This page is a reference, not medical advice. It describes what regulators and published research say. Talk to a doctor or dietitian about your own diet.
Regulatory status
Checked Sep 2026-
European Union Permitted EUR-Lex Reg. (EC) 1333/2008
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United Kingdom Permitted FSA retained EU law
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Canada Permitted Health Canada · Preservatives
Status reflects the named register on the date checked. It is not a safety rating. A country appears here once we've found this ingredient on its official list.
How we checkProducts
The 6 most-scanned of 334 products on Open Food Facts that list nisin.
- Eggs from plants JUST · 16 oz 3 additives
- Ramona’s heavenly houmous Ramona’s 5 additives
- Egg White Wraps Egglife · 6 oz 2 additives
- Baked Scalloped Potatoes Reser's Main St Bistro Select · 40 oz 1 additive
- Plant-Based Scramble (Liquid) East JUST Inc. · 12 fl oz 4 additives
- Chicken Salad Cape Cod Recipe · 40 oz 2 additives
References
- 1Nisin. Wikipedia. Accessed September 26, 2026.
- 2Field D, Fernandez de Ullivarri M, Ross RP, Hill C. After a century of nisin research - where are we now? FEMS Microbiol Rev. 2023;47(3). doi:10.1093/femsre/fuad023
- 3Yuan L, Wu S, Tian K, Wang S, Wu H, Qiao J. Nisin-relevant antimicrobial peptides: synthesis strategies and applications. Food Funct. 2024;15(19):9662-9677. doi:10.1039/d3fo05619h
- 4Stergiou VA, Thomas LV, Adams MR. Interactions of nisin with glutathione in a model protein system and meat. J Food Prot. 2006;69(4):951-6. doi:10.4315/0362-028x-69.4.951