E577Sequestrant
Potassium gluconate
What the research shows
No concerns
none of the findings here link it to harm
A potassium salt of the conjugate base of gluconic acid.1
- Vegan
- Vegetarian
- EU permitted
What research says
Studies in people
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Open question
Blood pressure and potassium2
In people, potassium gluconate supplements raised blood potassium the same as potatoes, but blood pressure did not change.
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Benefit
Calcium loss in urine3
In a feeding trial, people taking potassium gluconate lost less calcium in their urine than when on the control diet.
The signal at the top counts the findings in people and in animal and lab studies. A concern in studies of people outranks animal and lab studies, and “No concerns” needs at least one finding in people. When most findings in people point one way, the page leans that way (“Mostly”), and every finding is still shown. Findings whose study type is not stated are shown but not counted. This page is a reference, not medical advice. It describes what regulators and published research say. Talk to a doctor or dietitian about your own diet.
What expert reviews concluded
Expert panels that weigh all the research. Shown for context: the signal at the top does not count them.
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UN and WHO food additive experts (JECFA), 1998
No daily limit needed (“ADI not specified”, JECFA’s term for very low toxicity).
Regulatory status
Checked Sep 2026-
European Union Permitted EUR-Lex Reg. (EC) 1333/2008
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United Kingdom Permitted FSA retained EU law
Status reflects the named register on the date checked. It is not a safety rating. A country appears here once we've found this ingredient on its official list.
How we checkProducts
The 6 most-scanned of 20 products on Open Food Facts that list potassium gluconate.
- Chicken ceasar bacon baguette Pret · 1 Baguette 3 additives
- Posh Cheddar & Pickle Baguette Pret A Manger · 233 g 0 additives
- Italian Prosciutto Baguette Pret 0 additives
- Smoked Salmon, Egg Mayo & Avo Baguette Pret A Manger 0 additives
- Sandwich Avo Olive and Toms Baguette Pret · 237 g 0 additives
- GATORADE ENERGY BAR PEANUT BUTTER 2.1 oz Kunella · 500 g 4 additives
References
- 1Potassium gluconate. Wikipedia. Accessed September 26, 2026. CC BY-SA 4.0.
- 2Macdonald-Clarke CJ, Martin BR, McCabe LD, et al. Bioavailability of potassium from potatoes and potassium gluconate: a randomized dose response trial. Am J Clin Nutr. 2016;104(2):346-53. doi:10.3945/ajcn.115.127225
- 3Stone MS, Martin BR, Weaver CM. Short-Term Supplemental Dietary Potassium from Potato and Potassium Gluconate: Effect on Calcium Retention and Urinary pH in Pre-Hypertensive-to-Hypertensive Adults. Nutrients. 2021;13(12). doi:10.3390/nu13124399