E490

Propylene glycol

What the research shows

Unclear

the research on this page hasn’t settled it

A thick, clear liquid with a faintly sweet taste.1

Also used on skin: Propylene glycol (skin)

  • Vegan
  • Vegetarian

What research says

Studies in people

  • Open question

    Daily intake from drinks3

    Propylene glycol in drinks stays below the safe daily amount, even for children who drink a lot.

Study type not stated

Single cases of misuse or overdose

One person or one incident, such as an accidental overdose or a mistake in a kitchen or factory. They are real, but a single case does not show what happens at normal amounts, so the signal does not count them.

  • Harm from eating too much2

    A woman who ate large amounts of corn starch mixed with baking soda built up propylene glycol and became very ill.

  • Skin rash from food5

    A woman's skin rash flared up again after she ate foods containing propylene glycol.

How it’s made and used

  • How much we eat4

    Propylene glycol was found in most Korean foods tested, with bread adding the most to daily intake.

  • Daily intake from food6

    Propylene glycol was found in about a third of tested foods, mostly raw noodles, at levels well below the limit.

The signal at the top counts the findings in people and in animal and lab studies. A concern in studies of people outranks animal and lab studies, and “No concerns” needs at least one finding in people. When most findings in people point one way, the page leans that way (“Mostly”), and every finding is still shown. Findings whose study type is not stated are shown but not counted. This page is a reference, not medical advice. It describes what regulators and published research say. Talk to a doctor or dietitian about your own diet.

Regulatory status

Checked Sep 2026

Status reflects the named register on the date checked. It is not a safety rating. A country appears here once we've found this ingredient on its official list.

How we check

Products

The 6 most-scanned of 3,229 products on Open Food Facts that list propylene glycol.

  • Esența Vanilie Dr.oetker · 38 ml e 3 additives
  • vanilla extract Asda · 60 ml 2 additives
  • Buche des fetes 14 additives
  • Sweetened Coconut Flakes Great Value · 7 oz 2 additives
  • cvs cleansing wipes 8 additives
  • Mio Sport Berry Blast 8 additives

References

  1. 1Propylene glycol. Wikipedia. Accessed September 26, 2026. CC BY-SA 4.0.
  2. 2Peterson J, Stadlen R, Radke J. Propylene glycol toxicity from compulsive corn starch ingestion. Am J Emerg Med. 2022;53:286.e1-286.e3. doi:10.1016/j.ajem.2021.09.054
  3. 3Tran NL, Anderson MM, Jack MM. Tiered intake assessment for propylene glycol in beverages. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2025;42(3):317-325. doi:10.1080/19440049.2025.2449820
  4. 4Lim HS, Hwang JY, Choi E, Lee GY, Yun SS, Kang T. Assessment of the dietary intake of propylene glycol in the Korean population. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2016;33(8):1290-8. doi:10.1080/19440049.2016.1209576
  5. 5Lowther A, McCormick T, Nedorost S. Systemic contact dermatitis from propylene glycol. Dermatitis. 2008;19(2):105-8.
  6. 6Ishiwata H, Nishijima M, Fukasawa Y. Estimation of inorganic food additive (nitrite, nitrate and sulfur dioxide), antioxidant (BHA and BHT), processing agent (propylene glycol) and sweetener (sodium saccharin) concentrations in foods and their daily intake based on official inspection results in Japan in fiscal year 1998. Shokuhin Eiseigaku Zasshi. 2003;44(2):132-43. doi:10.3358/shokueishi.44.132
  7. 7Lewis AS, Boomhower SR, Marsh CM, Jack MM. Considerations for deriving a safe intake of propylene glycol. Food Chem Toxicol. 2024;186:114460. doi:10.1016/j.fct.2024.114460