E101Colour
Riboflavin
What the research shows
PrototypeNo concerns
none of the findings here link it to harm
3 health findings on this page, 2 in people · See the findings
A vitamin found in food, also called vitamin B2.
It is used as a food coloring agent.
Written from English Wikipedia1
- May not be vegan
- Vegetarian
- EU permitted
What research says
Studies in people
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Benefit
Women's fertility2
In women, eating more riboflavin was linked to a lower chance of infertility, though this shows only a connection.
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Benefit
Dementia risk in later life3
In Japanese adults, eating more riboflavin was linked to fewer cases of disabling dementia.
Animal and lab studies only
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Benefit
Gut inflammation in mice7
In animal studies, riboflavin and bacteria that make it reduced gut damage and inflammation in mice with colitis.
Study type not stated
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Benefit
Cancer risk and body protection4
Riboflavin may help lower the risk of some cancers and protect the body in other ways.
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Concern
Vitamin deficiency signs5
Not getting enough riboflavin can cause anaemia, high blood pressure and skin and mouth problems.
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Concern
How the body absorbs it6
Riboflavin is taken in through the gut, and not getting enough affects iron absorption and other body processes.
The signal at the top counts the findings in people and in animal and lab studies. A concern in studies of people outranks animal and lab studies, and “No concerns” needs at least two findings in people. Findings whose study type is not stated are shown but not counted. This page is a reference, not medical advice. It describes what regulators and published research say. Talk to a doctor or dietitian about your own diet.
Regulatory status
Checked Sep 2026-
United States Permitted FDA 21 CFR 73.450
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European Union Permitted EUR-Lex Reg. (EC) 1333/2008
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United Kingdom Permitted FSA retained EU law
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Canada Permitted Health Canada · Colouring Agents
Status reflects the named register on the date checked. It is not a safety rating.
How we checkProducts
The 6 most-scanned of 62,383 products on Open Food Facts that list riboflavin.
- Alpro Mandeldrink, Original 1L Alpro · 1 l 2 additives
- Weetabix Weetabix · 430 g 0 additives
- CORN FLAKES Kellogg's · 500 g 0 additives
- Alpro smooth subtle creamy oat alpro · 1 l 2 additives
- Marmite Yeast Extract Marmite · 250 g 0 additives
- Croissance réduit en sucre Jaouda · 500 ml 1 additive
References
- 1Riboflavin. Wikipedia. Accessed September 25, 2026.
- 2Zhao Z, Mao Z, Liu M, et al. Association between vitamin B2 intake and female infertility: a cross-sectional study. Sci Rep. 2025;15(1):23731. doi:10.1038/s41598-025-09161-1
- 3Kishida R, Yamagishi K, Maruyama K, et al. Dietary intake of folate, vitamin B6, vitamin B12, and riboflavin and the risk of incident dementia. Eur J Clin Nutr. 2025;79(11):1099-1105. doi:10.1038/s41430-025-01663-5
- 4Suwannasom N, Kao I, Pruß A, Georgieva R, Bäumler H. Riboflavin: The Health Benefits of a Forgotten Natural Vitamin. Int J Mol Sci. 2020;21(3). doi:10.3390/ijms21030950
- 5McNulty H, Pentieva K, Ward M. Causes and Clinical Sequelae of Riboflavin Deficiency. Annu Rev Nutr. 2023;43:101-122. doi:10.1146/annurev-nutr-061121-084407
- 6Thakur K, Tomar SK, Singh AK, Mandal S, Arora S. Riboflavin and health: A review of recent human research. Crit Rev Food Sci Nutr. 2017;57(17):3650-3660. doi:10.1080/10408398.2016.1145104
- 7Levit R, Savoy de Giori G, de Moreno de LeBlanc A, LeBlanc JG. Effect of riboflavin-producing bacteria against chemically induced colitis in mice. J Appl Microbiol. 2018;124(1):232-240. doi:10.1111/jam.13622