Shiitake
What the research shows
Unclear
the research on this page hasn’t settled it
An edible mushroom from East Asia.1
What research says
Studies in people
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Open question
Cholesterol and blood fats3
Eating shiitake bars cut triglycerides about 10% in people with borderline high cholesterol, though some sensitive people got a skin rash.
Animal and lab studies only
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Benefit
Gut inflammation and bowel disease7
In lab and animal studies, shiitake compounds reduced gut inflammation, but human evidence is limited.
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Benefit
Tooth decay prevention8
In lab studies, shiitake mushrooms may help prevent tooth decay, but more research is needed.
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No harm found
Pregnancy and fetal development9
In animal studies, pregnant rats fed shiitake showed no changes in their babies' body measurements.
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Benefit
Blood sugar after eating10
In lab studies, noodles with shiitake stem powder released less sugar during digestion than plain noodles.
Study type not stated
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Open question
Gut bacteria and cholesterol5
Shiitake may feed gut bacteria that make butyrate, and compounds in it are linked to cholesterol, but human proof is still thin.
Found in some samples or products
These come from where it was grown, how it was processed or cooked, or what it was made into. They are not about the ingredient itself, so the signal does not count them.
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Arsenic and cadmium levels6
Shiitake mushrooms grown in Poland contained arsenic and cadmium at levels that may be bad for people who eat them.
Single cases of misuse or overdose
One person or one incident, such as an accidental overdose or a mistake in a kitchen or factory. They are real, but a single case does not show what happens at normal amounts, so the signal does not count them.
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Skin rash after eating2
A woman got an itchy, streak-like rash on her trunk 48 hours after eating shiitake mushrooms.
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Skin rash from food4
Eating raw shiitake mushrooms can cause an itchy, whip-like rash on the body.
The signal at the top counts the findings in people and in animal and lab studies. A concern in studies of people outranks animal and lab studies, and “No concerns” needs at least one finding in people. When most findings in people point one way, the page leans that way (“Mostly”), and every finding is still shown. Findings whose study type is not stated are shown but not counted. This page is a reference, not medical advice. It describes what regulators and published research say. Talk to a doctor or dietitian about your own diet.
Products
The 6 most-scanned of 1,133 products on Open Food Facts that list shiitake.
- SHIN RAMYUN kpoptészta NONGSHIM · 120 g 9 additives
- Organic Swiss Vegetable Vegan Bouillon Powder Marigold · 140 g 0 additives
- This is super superfood This is · 250 0 additives
- organic supergreens fruits & vegetables zena greens 4 additives
- Granola Minis, Chocolate Chip & Mixed Berry Made Good 0 additives
- ORGANIC CHEWY GRANOLA BARS mixed berry MADEGOOD · 144 g (6 * 24 g) 0 additives
References
- 1shiitake: ingredient taxonomy entry. Open Food Facts.
- 2Rojas-Mejía DV, Serrano C. [Flagellate dermatitis caused by the intake of shiitake mushrooms. A case report and review of the literature]. Rev Alerg Mex. 2020;67(1):79-82. doi:10.29262/ram.v67i1.620
- 3Spim SRV, Pistila AMH, Pickler TB, Silva MT, Grotto D. Effects of Shiitake Culinary-Medicinal Mushroom, Lentinus edodes (Agaricomycetes), Bars on Lipid and Antioxidant Profiles in Individuals with Borderline High Cholesterol: A Double-Blind Randomized Clinical Trial. Int J Med Mushrooms. 2021;23(7):1-12. doi:10.1615/IntJMedMushrooms.2021038773
- 4Mulhall J, Elseth A, Perdue J, Pomerantz H, Brown B, Frasca D. Flagellate Dermatitis After Ingestion of Shiitake Mushrooms in a Healthy Female Living in the Southeastern United States. J Emerg Med. 2020;59(1):e13-e15. doi:10.1016/j.jemermed.2020.04.035
- 5Makkar S, Nehra K, Makker J, et al. Macromolecular Organization in Lentinula edodes: Integrating Co-Occurring Bioactives for Structure-Function Relationships Across Gut Microbiota and Host Metabolism. Compr Rev Food Sci Food Saf. 2026;25(4):e70536. doi:10.1111/1541-4337.70536
- 6Mleczek M, Siwulski M, Rzymski P, et al. Multi-elemental analysis of Lentinula edodes mushrooms available in trade. J Environ Sci Health B. 2017;52(3):196-205. doi:10.1080/03601234.2017.1261551
- 7Bugajewski M, Angerhoefer N, Pączek L, Kaleta B. Lentinula edodes as a Source of Bioactive Compounds with Therapeutical Potential in Intestinal Inflammation and Colorectal Cancer. Int J Mol Sci. 2025;26(7). doi:10.3390/ijms26073320
- 8Avinash J, Vinay S, Jha K, Das D, Goutham BS, Kumar G. The Unexplored Anticaries Potential of Shiitake Mushroom. Pharmacogn Rev. 2016;10(20):100-104. doi:10.4103/0973-7847.194039
- 9Camargo IF, Caetano ELA, Pickler TB, Gerenutti M, Grotto D. Shiitake Culinary-Medicinal Mushroom, Lentinus edodes (Agaricomycetes): Absence of Changes in Maternal Reproductive Performance and Embryofetal Development In Vivo. Int J Med Mushrooms. 2020;22(8):781-791. doi:10.1615/IntJMedMushrooms.2020035680
- 10Wang L, Zhao H, Brennan M, et al. In vitro gastric digestion antioxidant and cellular radical scavenging activities of wheat-shiitake noodles. Food Chem. 2020;330:127214. doi:10.1016/j.foodchem.2020.127214