E251Preservative
Sodium nitrate
What the research shows
Concerning
in animal and lab studies only
What research says
Studies in people
-
Benefit
Blood pressure and metabolism3
In animal and human studies, nitrate lowered blood pressure and improved blood sugar handling.
Animal and lab studies only
-
Concern
Stomach inflammation5
In mice, a high-sodium-nitrate diet caused stomach inflammation and changed stomach bacteria.
Found in some samples or products
These come from where it was grown, how it was processed or cooked, or what it was made into. They are not about the ingredient itself, so the signal does not count them.
-
Young children's nitrite intake4
In Swedish children, nitrate from food may turn into nitrite, and about 12% of 4-year-olds got more nitrite than advised.
The signal at the top counts the findings in people and in animal and lab studies. A concern in studies of people outranks animal and lab studies, and “No concerns” needs at least one finding in people. When most findings in people point one way, the page leans that way (“Mostly”), and every finding is still shown. Findings whose study type is not stated are shown but not counted. This page is a reference, not medical advice. It describes what regulators and published research say. Talk to a doctor or dietitian about your own diet.
What expert reviews concluded
Expert panels that weigh all the research. Shown for context: the signal at the top does not count them. IARC rates whether something can cause cancer at all, not how likely it is at the amounts in food.
-
UN and WHO food additive experts (JECFA), 1995
Acceptable daily intake: up to 3.7 mg per kg of body weight.
-
WHO cancer agency (IARC), 2006
For nitrate or nitrite eaten under conditions that form nitroso compounds in the body: probably causes cancer in people (Group 2A).
Regulatory status
Checked Sep 2026-
United States Permitted FDA 21 CFR 172.170
-
European Union Permitted EUR-Lex Reg. (EC) 1333/2008
-
United Kingdom Permitted FSA retained EU law
-
Canada Permitted Health Canada · Preservatives
Status reflects the named register on the date checked. It is not a safety rating.
How we checkProducts
The 6 most-scanned of 1,077 products on Open Food Facts that list sodium nitrate.
- Charlie Bingham Lasagne Charlie Bigham's · 690 g 4 additives
- Chicken, Leek & Smoked Bacon Pie Mark & Spencer · 500 g 4 additives
- Tortilla Rolls Crispy Cheese Lidl · 125 g 4 additives
- Lasagne for 1 Charlie Bigham's · 335 g 4 additives
- Slim Jim Original Conagra Brands · 8 g 3 additives
- Stonebaked Pepperoni Hand Stretched Pizza Sainsbury's 3 additives
References
- 1Sodium nitrate: ingredient taxonomy entry. Open Food Facts.
- 2Sodium nitrate. Wikipedia. Accessed September 26, 2026. CC BY-SA 4.0.
- 3Lundberg JO, Carlström M, Weitzberg E. Metabolic Effects of Dietary Nitrate in Health and Disease. Cell Metab. 2018;28(1):9-22. doi:10.1016/j.cmet.2018.06.007
- 4Larsson K, Darnerud PO, Ilbäck NG, Merino L. Estimated dietary intake of nitrite and nitrate in Swedish children. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2011;28(5):659-66. doi:10.1080/19440049.2011.555842
- 5Jiang L, Li T, Wu J, et al. Dietary nitrate drives gastritis by modulating gastric microbiota and metabolites. Cancer Biol Med. 2026;23(5):717-36. doi:10.20892/j.issn.2095-3941.2025.0679