Streptococcus thermophilus
What the research shows
No concerns
none of the findings here link it to harm
What research says
Studies in people
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Open question
Gut survival of probiotics3
Scientists often can't tell whether Streptococcus thermophilus found in stool was the probiotic or a look-alike germ.
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Benefit
Diarrhea severity in infants4
Infants fed formula fermented with Streptococcus thermophilus had less severe diarrhea, though how often it happened was the same.
Animal and lab studies only
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Benefit
Gut bacteria growth7
Streptococcus thermophilus makes folate, which helped certain gut bacteria grow.
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Benefit
Gut survival and germ-killing8
In lab studies, Streptococcus thermophilus from dahi survived acidic conditions and bile salts and killed some food-borne germs.
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Benefit
Immune system response9
Streptococcus thermophilus made human immune cells release a signal that calms inflammation.
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Benefit
Gut tumours in mice10
In mice, Streptococcus thermophilus reduced tumor formation, though it is unclear if it works the same way in people.
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Benefit
Liver health11
In animal studies, Streptococcus thermophilus helped keep liver blood markers normal in mice exposed to air pollution particles.
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Benefit
Gut infection defence12
In lab studies, one Streptococcus thermophilus strain kept Listeria, Staphylococcus and Salmonella germs from sticking to gut cells better than another strain.
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Benefit
Alcohol-related liver damage13
In animal studies, Streptococcus thermophilus improved liver tests and reduced liver fat and inflammation in mice with alcohol-related liver damage.
How it’s made and used
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Gut bacteria after eating5
Streptococcus thermophilus showed up in people's stool during and after eating yogurt or a supplement, then faded away.
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Gut bacteria survival6
Streptococcus thermophilus was found in the guts of many healthy adults and can stay there for days.
The signal at the top counts the findings in people and in animal and lab studies. A concern in studies of people outranks animal and lab studies, and “No concerns” needs at least one finding in people. When most findings in people point one way, the page leans that way (“Mostly”), and every finding is still shown. Findings whose study type is not stated are shown but not counted. This page is a reference, not medical advice. It describes what regulators and published research say. Talk to a doctor or dietitian about your own diet.
Products
The 6 most-scanned of 2,910 products on Open Food Facts that list streptococcus thermophilus.
- Nature aux Amandes - Végétal soja & amande Alpro · 0.5 kg 5 additives
- Heidelbeere Alpro · 500 g 4 additives
- Total 0% FAGE · 450 g 0 additives
- Fermented Coconut Yoghurt Alternative The Coconut Collab · 350 g 1 additive
- Greek 0% Fat Authentic Greek Yogurt Brooklea · 500 g 0 additives
- Greek 10% fat authentic yogurt Brooklea · 500 g 0 additives
References
- 1Streptococcus thermophilus: ingredient taxonomy entry. Open Food Facts.
- 2Streptococcus thermophilus. Wikipedia. Accessed September 29, 2026. CC BY-SA 4.0.
- 3Martinović A, Cocuzzi R, Arioli S, Mora D. Streptococcus thermophilus: To Survive, or Not to Survive the Gastrointestinal Tract, That Is the Question! Nutrients. 2020;12(8). doi:10.3390/nu12082175
- 4Thibault H, Aubert-Jacquin C, Goulet O. Effects of long-term consumption of a fermented infant formula (with Bifidobacterium breve c50 and Streptococcus thermophilus 065) on acute diarrhea in healthy infants. J Pediatr Gastroenterol Nutr. 2004;39(2):147-52. doi:10.1097/00005176-200408000-00004
- 5Brigidi P, Swennen E, Vitali B, Rossi M, Matteuzzi D. PCR detection of Bifidobacterium strains and Streptococcus thermophilus in feces of human subjects after oral bacteriotherapy and yogurt consumption. Int J Food Microbiol. 2003;81(3):203-9. doi:10.1016/s0168-1605(02)00245-3
- 6Lugli GA, Argentini C, Tarracchini C, et al. Host interactions of Lactococcus lactis and Streptococcus thermophilus support their adaptation to the human gut microbiota. Appl Environ Microbiol. 2025;91(12):e0154725. doi:10.1128/aem.01547-25
- 7Nam EH, Lee M, Kim D, Jung YH, Yang J, Shin M. Folate Production by Streptococcus thermophilus IDCC 2201 and Its Impact on Human Gut Microbiota. J Microbiol Biotechnol. 2025;35:e2502045. doi:10.4014/jmb.2502.02045
- 8Mahmood T, Masud T, Imran M, Ahmed I, Khalid N. Selection and characterization of probiotic culture of Streptococcus thermophilus from dahi. Int J Food Sci Nutr. 2013;64(4):494-501. doi:10.3109/09637486.2012.749840
- 9Latvala S, Miettinen M, Kekkonen RA, Korpela R, Julkunen I. Lactobacillus rhamnosus GG and Streptococcus thermophilus induce suppressor of cytokine signalling 3 (SOCS3) gene expression directly and indirectly via interleukin-10 in human primary macrophages. Clin Exp Immunol. 2011;165(1):94-103. doi:10.1111/j.1365-2249.2011.04408.x
- 10Li Q, Hu W, Liu WX, et al. Streptococcus thermophilus Inhibits Colorectal Tumorigenesis Through Secreting β-Galactosidase. Gastroenterology. 2021;160(4):1179-1193.e14. doi:10.1053/j.gastro.2020.09.003
- 11Jeon MG, Kim TR, Lee JY, et al. Hepatoprotective Effects of Streptococcus thermophilus LM1012 in Mice Exposed to Air Pollutants. J Med Food. 2020;23(8):852-861. doi:10.1089/jmf.2019.4636
- 12Guigas C, Faulhaber K, Duerbeck D, Neve H, Heller KJ. Prophage-mediated modulation of interaction of Streptococcus thermophilus J34 with human intestinal epithelial cells and its competition against human pathogens. Benef Microbes. 2016;7(2):289-97. doi:10.3920/BM2015.0108
- 13Xia J, Cheng Y, Sang L, Wei Q, Li Q, Chang B. Streptococcus thermophilus alleviates fatty liver disease by regulating gut microbiota, lipid metabolism, and inflammation. Int Immunopharmacol. 2026;168(Pt 2):115905. doi:10.1016/j.intimp.2025.115905