Trehalose
What the research shows
No concerns
none of the findings here link it to harm
What research says
Studies in people
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Benefit
Blood sugar and insulin3
In overweight people, trehalose caused a smaller rise in blood sugar and insulin than glucose.
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Benefit
Hip fracture healing5
In adults with surgically treated pertrochanteric fractures, trehalose supplements improved X-ray healing and hip function at 12 weeks.
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Benefit
Blood sugar after meals7
In people with impaired glucose tolerance, trehalose caused a smaller rise in blood sugar and insulin than glucose did.
Study type not stated
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Benefit
Blood sugar control8
Trehalose is a natural sweet sugar that may help keep blood sugar steady in people with diabetes.
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Open question
Gut bacteria and metabolism9
Trehalose is a sugar that seems to change gut bacteria and how the body handles energy, but how is still being studied.
How it’s made and used
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Fuel use during exercise4
In people cycling for hours, trehalose was burned for fuel more slowly than maltose.
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Cycling endurance6
In cyclists, trehalose during a long ride improved time-trial performance compared with water.
The signal at the top counts the findings in people and in animal and lab studies. A concern in studies of people outranks animal and lab studies, and “No concerns” needs at least one finding in people. When most findings in people point one way, the page leans that way (“Mostly”), and every finding is still shown. Findings whose study type is not stated are shown but not counted. This page is a reference, not medical advice. It describes what regulators and published research say. Talk to a doctor or dietitian about your own diet.
Products
The 6 most-scanned of 225 products on Open Food Facts that list trehalose.
- Mango & Passionfruit Mochi Ice Cream Little Moons · 192 g 5 additives
- Honey Roasted Pistachio Mochi Ice Cream Little Moons · 6 x 32 g 6 additives
- ALOE VERA DRINK white real aloe pieces Grace · 500 ml 4 additives
- Very Berry Mochi Sorbet Little Moons refreshos 6 additives
- Japanese style mochi Lidl · 6 servings 210 g e 5 additives
- Pop Corn Mochi Little Moons · 6 x 32 g 10 additives
References
- 1trehalose: ingredient taxonomy entry. Open Food Facts.
- 2Trehalose. Wikipedia. Accessed September 30, 2026. CC BY-SA 4.0.
- 3van Can JG, Ijzerman TH, van Loon LJ, Brouns F, Blaak EE. Reduced glycaemic and insulinaemic responses following trehalose ingestion: implications for postprandial substrate use. Br J Nutr. 2009;102(10):1395-9. doi:10.1017/S000711450999050X
- 4Venables MC, Brouns F, Jeukendrup AE. Oxidation of maltose and trehalose during prolonged moderate-intensity exercise. Med Sci Sports Exerc. 2008;40(9):1653-9. doi:10.1249/MSS.0b013e318175716c
- 5Mehrvar A, Razani HO, Zavareh AT, et al. Effects of trehalose supplementation on bone healing, physical function, and pain in patients with pertrochanteric fractures: a randomized controlled trial. Sci Rep. 2026;16(1). doi:10.1038/s41598-026-56086-4
- 6de Oliveira NG, de Oliveira LF, da Silva RP, et al. Trehalose Improved 20-min Cycling Time-Trial Performance After 100-min Cycling in Amateur Cyclists. Int J Sport Nutr Exerc Metab. 2024;34(4):199-206. doi:10.1123/ijsnem.2023-0241
- 7van Can JG, van Loon LJ, Brouns F, Blaak EE. Reduced glycaemic and insulinaemic responses following trehalose and isomaltulose ingestion: implications for postprandial substrate use in impaired glucose-tolerant subjects. Br J Nutr. 2012;108(7):1210-7. doi:10.1017/S0007114511006714
- 8Sokołowska E, Sadowska A, Sawicka D, Kotulska-Bąblińska I, Car H. A head-to-head comparison review of biological and toxicological studies of isomaltulose, d-tagatose, and trehalose on glycemic control. Crit Rev Food Sci Nutr. 2022;62(21):5679-5704. doi:10.1080/10408398.2021.1895057
- 9Zhang Y, DeBosch BJ. Microbial and metabolic impacts of trehalose and trehalose analogues. Gut Microbes. 2020;11(5):1475-1482. doi:10.1080/19490976.2020.1750273