Wheat flour
What the research shows
Mostly no concerns
most studies in people found no harm or a benefit
What research says
Studies in people
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No harm found
Anaemia and iron levels3
In people, wheat flour with added iron may make little or no difference to anaemia or iron deficiency.
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Open question
Vitamin A deficiency4
Mill-rolled wheat flour can be fortified with vitamin A, though big gaps remain in what is known.
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Benefit
Anaemia in the general population5
Iron-fortified wheat flour may lower anaemia risk, but scientists do not yet know its effects on other health outcomes.
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Concern
Heart health and bread7
Eating more refined wheat flour bread has been linked to higher risk of heart problems and death.
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Benefit
Calcium intake shortfall9
Adding calcium to wheat flour could cut low calcium intake in many Argentinians, though older people may still fall short.
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Open question
Zinc levels in the body10
Scientists are testing whether wheat flour with extra zinc helps raise zinc levels in women and teens.
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Benefit
Iron absorption from food11
In women, wheat flour foods fortified with iron gave better iron absorption when eaten with lemonade.
Animal and lab studies only
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Benefit
Fibre in white bread20
White flour could be bred to hold more fibre, which may slow how fast bread sugar hits the blood.
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Benefit
Colon cancer cells21
In lab studies, some wheat flours slowed colon cancer cells, but this was not tested in people.
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Benefit
Mineral absorption from bread22
Wheat flour keeps more iron and zinc when wholemeal, and bread making helps the body absorb them.
Study type not stated
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Benefit
Nutrient levels in fortified foods13
Fortified wheat flour and other foods can add vitamins and minerals to diets without going over safe amounts.
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No harm found
Heavy metal exposure levels15
Wheat flour contained small amounts of metals like lead and cadmium, but well below the levels considered risky.
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Open question
Nutrient levels in noodles16
Instant noodles made with fortified wheat flour kept most added vitamins and minerals, though not thiamin.
Found in some samples or products
These come from where it was grown, how it was processed or cooked, or what it was made into. They are not about the ingredient itself, so the signal does not count them.
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Grain contamination near smelters14
Wheat flour grown near a lead smelter held cadmium and lead above safe levels, especially in whole wheat flour.
How it’s made and used
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Toxin levels in food6
Most wheat flour samples contained deoxynivalenol, but eating it added little to people's daily intake.
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Fortification programs falling short8
Most countries add the wrong kind of iron to wheat flour, so these programs likely do little to raise iron levels.
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Cake texture and taste12
Swapping wheat flour for green pea waste flour made cakes denser and harder, and tasters liked them less above a certain level.
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Dough thickening behavior17
Adding buckwheat or millet to wheat flour changes how the dough thickens, sets and holds together.
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Gluten protein makeup18
In lab studies, wheat flour gliadin extract also contained glutenins and avenin-like proteins.
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How much the body absorbs19
In lab studies, only a small share of cooked whole-wheat pasta's polyphenols may be absorbed by the small intestine.
The signal at the top counts the findings in people and in animal and lab studies. A concern in studies of people outranks animal and lab studies, and “No concerns” needs at least one finding in people. When most findings in people point one way, the page leans that way (“Mostly”), and every finding is still shown. Findings whose study type is not stated are shown but not counted. This page is a reference, not medical advice. It describes what regulators and published research say. Talk to a doctor or dietitian about your own diet.
References
- 1wheat flour: ingredient taxonomy entry. Open Food Facts.
- 2Wheat flour. Wikipedia. Accessed September 26, 2026. CC BY-SA 4.0.
- 3Field MS, Mithra P, Estevez D, Peña-Rosas JP. Wheat flour fortification with iron for reducing anaemia and improving iron status in populations. Cochrane Database Syst Rev. 2020;7(7):CD011302. doi:10.1002/14651858.CD011302.pub2
- 4Klemm RD, West KP Jr, Palmer AC, et al. Vitamin A fortification of wheat flour: considerations and current recommendations. Food Nutr Bull. 2010;31(1 Suppl):S47-61. doi:10.1177/15648265100311S105
- 5Field MS, Mithra P, Peña-Rosas JP. Wheat flour fortification with iron and other micronutrients for reducing anaemia and improving iron status in populations. Cochrane Database Syst Rev. 2021;1(1):CD011302. doi:10.1002/14651858.CD011302.pub3
- 6Li F, Jiang D, Zhou J, Chen J, Li W, Zheng F. Mycotoxins in wheat flour and intake assessment in Shandong province of China. Food Addit Contam Part B Surveill. 2016;9(3):170-5. doi:10.1080/19393210.2016.1154109
- 7Wang Y, Jian C. Sustainable plant-based ingredients as wheat flour substitutes in bread making. NPJ Sci Food. 2022;6(1):49. doi:10.1038/s41538-022-00163-1
- 8Hurrell R, Ranum P, de Pee S, et al. Revised recommendations for iron fortification of wheat flour and an evaluation of the expected impact of current national wheat flour fortification programs. Food Nutr Bull. 2010;31(1 Suppl):S7-21. doi:10.1177/15648265100311S102
- 9Cormick G, Romero IB, Puchulu MB, et al. A simulation study to improve calcium intake through wheat flour fortification. Public Health Nutr. 2024;27(1):e159. doi:10.1017/S1368980024001228
- 10Das JK, Padhani ZA, Khan M, et al. Efficacy of Zinc Fortified and Fermented Wheat Flour (EZAFFAW): A randomized controlled trial protocol. PLoS One. 2024;19(6):e0304462. doi:10.1371/journal.pone.0304462
- 11Olivares M, Pizarro F, Hertrampf E, Fuenmayor G, Estévez E. Iron absorption from wheat flour: effects of lemonade and chamomile infusion. Nutrition. 2007;23(4):296-300. doi:10.1016/j.nut.2006.04.014
- 12Sallam YI, El-Salam EAEA, Abaza AG. Green pea waste flour as a wheat flour partial replacer in pound cake: Batter rheology behavior and cake quality properties. Acta Sci Pol Technol Aliment. 2021;20(1):67-78. doi:10.17306/J.AFS.0838
- 13Pachón H, Reynolds B, Duong M, et al. The Potential Contribution of Fortified Maize Flour, Oil, Rice, Salt, and Wheat Flour to Estimated Average Requirements and Tolerable Upper Intake Levels for 15 Nutrients in 153 Countries. Nutrients. 2021;13(2). doi:10.3390/nu13020579
- 14Li L, Zhang Y, Ippolito JA, Xing W, Tu C. Lead smelting alters wheat flour heavy metal concentrations and health risks. J Environ Qual. 2021;50(2):454-464. doi:10.1002/jeq2.20198
- 15Tejera RL, Luis G, González-Weller D, et al. Metals in wheat flour; comparative study and safety control. Nutr Hosp. 2013;28(2):506-13. doi:10.3305/nh.2013.28.2.6287
- 16Bronder KL, Zimmerman SL, van den Wijngaart A, Codling K, Johns KA, Pachón H. Instant noodles made with fortified wheat flour to improve micronutrient intake in Asia: a review of simulation, nutrient retention and sensory studies. Asia Pac J Clin Nutr. 2017;26(2):191-201. doi:10.6133/apjcn.122015.06
- 17Wu K, Gan R, Dai S, Cai YZ, Corke H, Zhu F. Buckwheat and Millet Affect Thermal, Rheological, and Gelling Properties of Wheat Flour. J Food Sci. 2016;81(3):E627-36. doi:10.1111/1750-3841.13240
- 18Perez-Gregorio MR, Días R, Mateus N, de Freitas V. Chromatographic and mass spectrometry analysis of wheat flour prolamins, the causative compounds of celiac disease. Food Funct. 2017;8(8):2712-2721. doi:10.1039/c7fo00266a
- 19Podio NS, Baroni MV, Pérez GT, Wunderlin DA. Assessment of bioactive compounds and their in vitro bioaccessibility in whole-wheat flour pasta. Food Chem. 2019;293:408-417. doi:10.1016/j.foodchem.2019.04.117
- 20Shewry PR, Joy EJM, De La Revilla LS, Hansen A, Brennan J, Lovegrove A. Increasing fibre in white flour and bread: Implications for health and processing. Nutr Bull. 2023;48(4):587-593. doi:10.1111/nbu.12648
- 21Lv J, Yu L, Lu Y, et al. Phytochemical compositions, and antioxidant properties, and antiproliferative activities of wheat flour. Food Chem. 2012;135(2):325-31. doi:10.1016/j.foodchem.2012.04.141
- 22Ciccolini V, Pellegrino E, Coccina A, et al. Biofortification with Iron and Zinc Improves Nutritional and Nutraceutical Properties of Common Wheat Flour and Bread. J Agric Food Chem. 2017;65(27):5443-5452. doi:10.1021/acs.jafc.7b01176