Wheat flour

What the research shows

Mostly no concerns

most studies in people found no harm or a benefit

A powder made by grinding wheat.

It gives dough its elasticity and chew.12

What research says

Studies in people

  • No harm found

    Anaemia and iron levels3

    In people, wheat flour with added iron may make little or no difference to anaemia or iron deficiency.

  • Open question

    Vitamin A deficiency4

    Mill-rolled wheat flour can be fortified with vitamin A, though big gaps remain in what is known.

  • Benefit

    Anaemia in the general population5

    Iron-fortified wheat flour may lower anaemia risk, but scientists do not yet know its effects on other health outcomes.

  • Concern

    Heart health and bread7

    Eating more refined wheat flour bread has been linked to higher risk of heart problems and death.

  • Benefit

    Calcium intake shortfall9

    Adding calcium to wheat flour could cut low calcium intake in many Argentinians, though older people may still fall short.

  • Open question

    Zinc levels in the body10

    Scientists are testing whether wheat flour with extra zinc helps raise zinc levels in women and teens.

  • Benefit

    Iron absorption from food11

    In women, wheat flour foods fortified with iron gave better iron absorption when eaten with lemonade.

Animal and lab studies only

  • Benefit

    Fibre in white bread20

    White flour could be bred to hold more fibre, which may slow how fast bread sugar hits the blood.

  • Benefit

    Colon cancer cells21

    In lab studies, some wheat flours slowed colon cancer cells, but this was not tested in people.

  • Benefit

    Mineral absorption from bread22

    Wheat flour keeps more iron and zinc when wholemeal, and bread making helps the body absorb them.

Study type not stated

Found in some samples or products

These come from where it was grown, how it was processed or cooked, or what it was made into. They are not about the ingredient itself, so the signal does not count them.

How it’s made and used

  • Toxin levels in food6

    Most wheat flour samples contained deoxynivalenol, but eating it added little to people's daily intake.

  • Fortification programs falling short8

    Most countries add the wrong kind of iron to wheat flour, so these programs likely do little to raise iron levels.

  • Cake texture and taste12

    Swapping wheat flour for green pea waste flour made cakes denser and harder, and tasters liked them less above a certain level.

  • Dough thickening behavior17

    Adding buckwheat or millet to wheat flour changes how the dough thickens, sets and holds together.

  • Gluten protein makeup18

    In lab studies, wheat flour gliadin extract also contained glutenins and avenin-like proteins.

  • How much the body absorbs19

    In lab studies, only a small share of cooked whole-wheat pasta's polyphenols may be absorbed by the small intestine.

The signal at the top counts the findings in people and in animal and lab studies. A concern in studies of people outranks animal and lab studies, and “No concerns” needs at least one finding in people. When most findings in people point one way, the page leans that way (“Mostly”), and every finding is still shown. Findings whose study type is not stated are shown but not counted. This page is a reference, not medical advice. It describes what regulators and published research say. Talk to a doctor or dietitian about your own diet.

References

  1. 1wheat flour: ingredient taxonomy entry. Open Food Facts.
  2. 2Wheat flour. Wikipedia. Accessed September 26, 2026. CC BY-SA 4.0.
  3. 3Field MS, Mithra P, Estevez D, Peña-Rosas JP. Wheat flour fortification with iron for reducing anaemia and improving iron status in populations. Cochrane Database Syst Rev. 2020;7(7):CD011302. doi:10.1002/14651858.CD011302.pub2
  4. 4Klemm RD, West KP Jr, Palmer AC, et al. Vitamin A fortification of wheat flour: considerations and current recommendations. Food Nutr Bull. 2010;31(1 Suppl):S47-61. doi:10.1177/15648265100311S105
  5. 5Field MS, Mithra P, Peña-Rosas JP. Wheat flour fortification with iron and other micronutrients for reducing anaemia and improving iron status in populations. Cochrane Database Syst Rev. 2021;1(1):CD011302. doi:10.1002/14651858.CD011302.pub3
  6. 6Li F, Jiang D, Zhou J, Chen J, Li W, Zheng F. Mycotoxins in wheat flour and intake assessment in Shandong province of China. Food Addit Contam Part B Surveill. 2016;9(3):170-5. doi:10.1080/19393210.2016.1154109
  7. 7Wang Y, Jian C. Sustainable plant-based ingredients as wheat flour substitutes in bread making. NPJ Sci Food. 2022;6(1):49. doi:10.1038/s41538-022-00163-1
  8. 8Hurrell R, Ranum P, de Pee S, et al. Revised recommendations for iron fortification of wheat flour and an evaluation of the expected impact of current national wheat flour fortification programs. Food Nutr Bull. 2010;31(1 Suppl):S7-21. doi:10.1177/15648265100311S102
  9. 9Cormick G, Romero IB, Puchulu MB, et al. A simulation study to improve calcium intake through wheat flour fortification. Public Health Nutr. 2024;27(1):e159. doi:10.1017/S1368980024001228
  10. 10Das JK, Padhani ZA, Khan M, et al. Efficacy of Zinc Fortified and Fermented Wheat Flour (EZAFFAW): A randomized controlled trial protocol. PLoS One. 2024;19(6):e0304462. doi:10.1371/journal.pone.0304462
  11. 11Olivares M, Pizarro F, Hertrampf E, Fuenmayor G, Estévez E. Iron absorption from wheat flour: effects of lemonade and chamomile infusion. Nutrition. 2007;23(4):296-300. doi:10.1016/j.nut.2006.04.014
  12. 12Sallam YI, El-Salam EAEA, Abaza AG. Green pea waste flour as a wheat flour partial replacer in pound cake: Batter rheology behavior and cake quality properties. Acta Sci Pol Technol Aliment. 2021;20(1):67-78. doi:10.17306/J.AFS.0838
  13. 13Pachón H, Reynolds B, Duong M, et al. The Potential Contribution of Fortified Maize Flour, Oil, Rice, Salt, and Wheat Flour to Estimated Average Requirements and Tolerable Upper Intake Levels for 15 Nutrients in 153 Countries. Nutrients. 2021;13(2). doi:10.3390/nu13020579
  14. 14Li L, Zhang Y, Ippolito JA, Xing W, Tu C. Lead smelting alters wheat flour heavy metal concentrations and health risks. J Environ Qual. 2021;50(2):454-464. doi:10.1002/jeq2.20198
  15. 15Tejera RL, Luis G, González-Weller D, et al. Metals in wheat flour; comparative study and safety control. Nutr Hosp. 2013;28(2):506-13. doi:10.3305/nh.2013.28.2.6287
  16. 16Bronder KL, Zimmerman SL, van den Wijngaart A, Codling K, Johns KA, Pachón H. Instant noodles made with fortified wheat flour to improve micronutrient intake in Asia: a review of simulation, nutrient retention and sensory studies. Asia Pac J Clin Nutr. 2017;26(2):191-201. doi:10.6133/apjcn.122015.06
  17. 17Wu K, Gan R, Dai S, Cai YZ, Corke H, Zhu F. Buckwheat and Millet Affect Thermal, Rheological, and Gelling Properties of Wheat Flour. J Food Sci. 2016;81(3):E627-36. doi:10.1111/1750-3841.13240
  18. 18Perez-Gregorio MR, Días R, Mateus N, de Freitas V. Chromatographic and mass spectrometry analysis of wheat flour prolamins, the causative compounds of celiac disease. Food Funct. 2017;8(8):2712-2721. doi:10.1039/c7fo00266a
  19. 19Podio NS, Baroni MV, Pérez GT, Wunderlin DA. Assessment of bioactive compounds and their in vitro bioaccessibility in whole-wheat flour pasta. Food Chem. 2019;293:408-417. doi:10.1016/j.foodchem.2019.04.117
  20. 20Shewry PR, Joy EJM, De La Revilla LS, Hansen A, Brennan J, Lovegrove A. Increasing fibre in white flour and bread: Implications for health and processing. Nutr Bull. 2023;48(4):587-593. doi:10.1111/nbu.12648
  21. 21Lv J, Yu L, Lu Y, et al. Phytochemical compositions, and antioxidant properties, and antiproliferative activities of wheat flour. Food Chem. 2012;135(2):325-31. doi:10.1016/j.foodchem.2012.04.141
  22. 22Ciccolini V, Pellegrino E, Coccina A, et al. Biofortification with Iron and Zinc Improves Nutritional and Nutraceutical Properties of Common Wheat Flour and Bread. J Agric Food Chem. 2017;65(27):5443-5452. doi:10.1021/acs.jafc.7b01176