Whey
What the research shows
No concerns
none of the findings here link it to harm*
*Allergies present
The liquid left after milk is curdled and strained.1
- Not vegan
- May not be vegetarian
What research says
Studies in people
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Benefit
Muscle strength in older adults2
Whey protein helped older people who were frail or sarcopenic gain muscle and walk faster, but did nothing for healthy older people.
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Benefit
Muscle mass as we age3
Whey protein helps build and keep muscle, especially with exercise, and may slow muscle loss with age.
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Benefit
Muscle strength in older women4
In postmenopausal women, whey protein helped arm strength and leg muscle only when paired with resistance training.
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Benefit
Muscle recovery after exercise5
In young, healthy adults, whey protein had small to medium benefits for muscle function recovery after hard workouts.
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No harm found
Acne severity in men6
In men with acne, whey protein did not make acne worse over six months.
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Benefit
Muscle soreness after exercise7
In men who exercised hard, whey protein lowered blood signs of muscle damage, but soreness and fitness stayed the same.
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Benefit
Muscle soreness after running8
In runners, whey protein was linked to lower muscle damage markers after a marathon and longer distances at 9 and 12 minutes.
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Benefit
Muscle soreness after exercise9
In active women, four days of whey protein hydrolysate improved flexibility and strength recovery after hard exercise.
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Benefit
Muscle strength and mass in older adults10
In older people with muscle loss, whey protein plus leucine and vitamin D added muscle, but strength improved only with exercise too.
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Benefit
Muscle loss with age11
In older adults, leucine-enriched whey protein plus resistance training increased lean muscle mass, strength and physical performance.
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Benefit
Muscle building after exercise12
In healthy adults, whey protein taken with exercise boosted muscle protein building, especially when taken before or right after a workout.
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Open question
Kidney stone risk13
In healthy people, whey protein did not change average kidney stone risk factors, but some individuals saw big shifts.
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Benefit
Muscle and body fat after workouts14
In people doing strength training, whey protein after workouts helped build lean muscle and lose fat.
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Open question
Baby growth and stools15
Babies fed whey formula grew the same as others, but their stools were different.
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Benefit
Muscle mass in older adults16
In older people in care homes, whey protein plus vitamin D and strength training improved muscle mass.
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Open question
Blood pressure18
Whey protein drinks lowered a blood enzyme in people, but blood pressure itself did not change.
Animal and lab studies only
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Benefit
Cancer treatment support24
Whey protein has shown anti-cancer effects in lab and animal studies, but human studies are still in their early days.
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Benefit
Muscle and liver cells25
In lab studies, whey peptides crossed a gut cell barrier and fought free radicals in muscle and liver cells.
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Benefit
Thyroid health in rats26
In animal studies, whey protein raised antioxidant levels in rats with an underactive thyroid.
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Benefit
Milk protein allergy27
In animal studies, whey-based baby formula with certain broken-down milk proteins reduced allergy sensitization, but not all whey formulas work the same.
Study type not stated
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Concern
Kidney and liver health19
Taking whey protein in large amounts for a long time may affect the kidneys and liver.
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Benefit
Gut and brain health20
Acid whey may help gut health and babies' brain development, but scientists are still studying it.
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Benefit
Dairy waste disposal22
Cheese whey, a byproduct of cheese-making, can be used to make health-promoting drinks and vinegar.
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Concern
Mineral levels in protein powders23
Whey protein powders can carry minerals like calcium and sodium, and heavy daily scooping may push some past daily recommended amounts.
Allergies and intolerances
These are about people with an allergy, an intolerance or coeliac disease. The signal is about the ingredient itself, and these are about the person eating it, so the signal does not count them.
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Blood immune complexes17
People allergic to milk had higher levels of immune complexes made against whey in their blood.
How it’s made and used
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Food texture and mixing21
Whey proteins mixed with plant compounds can change how they foam, emulsify and act as antioxidants.
The signal at the top counts the findings in people and in animal and lab studies. A concern in studies of people outranks animal and lab studies, and “No concerns” needs at least one finding in people. When most findings in people point one way, the page leans that way (“Mostly”), and every finding is still shown. Findings whose study type is not stated are shown but not counted. This page is a reference, not medical advice. It describes what regulators and published research say. Talk to a doctor or dietitian about your own diet.
Products
The 6 most-scanned of 40,094 products on Open Food Facts that list whey.
- Prince Goût Chocolat au blé complet Mondelez · 300 g 3 additives
- PESTO alla GENOVESE Barilla · 190 g e 1 additive
- Pesto Rosso BARILLA · 200 g 1 additive
- Chocolate con leche y almendras Maruja · 150 g 1 additive
- Poulain Poulain · 400 g 1 additive
- Granola L'Original LU · 200 g e 5 additives
References
- 1whey: ingredient taxonomy entry. Open Food Facts.
- 2Nasimi N, Sohrabi Z, Nunes EA, et al. Whey Protein Supplementation with or without Vitamin D on Sarcopenia-Related Measures: A Systematic Review and Meta-Analysis. Adv Nutr. 2023;14(4):762-773. doi:10.1016/j.advnut.2023.05.011
- 3Devries MC, Phillips SM. Supplemental protein in support of muscle mass and health: advantage whey. J Food Sci. 2015;80 Suppl 1:A8-A15. doi:10.1111/1750-3841.12802
- 4Kuo YY, Chang HY, Huang YC, Liu CW. Effect of Whey Protein Supplementation in Postmenopausal Women: A Systematic Review and Meta-Analysis. Nutrients. 2022;14(19). doi:10.3390/nu14194210
- 5Davies RW, Carson BP, Jakeman PM. The Effect of Whey Protein Supplementation on the Temporal Recovery of Muscle Function Following Resistance Training: A Systematic Review and Meta-Analysis. Nutrients. 2018;10(2). doi:10.3390/nu10020221
- 6Sompochpruetikul K, Khongcharoensombat T, Chongpison Y, et al. Whey protein and male acne: A double-blind, randomized controlled trial. J Dermatol. 2024;51(7):1022-1025. doi:10.1111/1346-8138.17109
- 7Nieman DC, Zwetsloot KA, Simonson AJ, et al. Effects of Whey and Pea Protein Supplementation on Post-Eccentric Exercise Muscle Damage: A Randomized Trial. Nutrients. 2020;12(8). doi:10.3390/nu12082382
- 8Huang WC, Chang YC, Chen YM, et al. Whey Protein Improves Marathon-Induced Injury and Exercise Performance in Elite Track Runners. Int J Med Sci. 2017;14(7):648-654. doi:10.7150/ijms.19584
- 9Brown MA, Stevenson EJ, Howatson G. Whey protein hydrolysate supplementation accelerates recovery from exercise-induced muscle damage in females. Appl Physiol Nutr Metab. 2018;43(4):324-330. doi:10.1139/apnm-2017-0412
- 10Chang MC, Choo YJ. Effects of Whey Protein, Leucine, and Vitamin D Supplementation in Patients with Sarcopenia: A Systematic Review and Meta-Analysis. Nutrients. 2023;15(3). doi:10.3390/nu15030521
- 11Ijaz A, Ain HBU, Tufail T, et al. Enhancing Muscle Quality: Exploring Leucine and Whey Protein in Sarcopenic Individuals. J Cachexia Sarcopenia Muscle. 2025;16(5):e70060. doi:10.1002/jcsm.70060
- 12Ji X, Ye X, Ji S, et al. Whey Protein Supplementation Combined with Exercise on Muscle Protein Synthesis and the AKT/mTOR Pathway in Healthy Adults: A Systematic Review and Meta-Analysis. Nutrients. 2025;17(16). doi:10.3390/nu17162579
- 13Hattori CM, Tiselius HG, Heilberg IP. Whey protein and albumin effects upon urinary risk factors for stone formation. Urolithiasis. 2017;45(5):421-428. doi:10.1007/s00240-017-0975-0
- 14Sharp MH, Lowery RP, Shields KA, et al. The Effects of Beef, Chicken, or Whey Protein After Workout on Body Composition and Muscle Performance. J Strength Cond Res. 2018;32(8):2233-2242. doi:10.1519/JSC.0000000000001936
- 15Harrison GG, Graver EJ, Vargas M, Churella HR, Paule CL. Growth and adiposity of term infants fed whey-predominant or casein-predominant formulas or human milk. J Pediatr Gastroenterol Nutr. 1987;6(5):739-47. doi:10.1097/00005176-198709000-00014
- 16Colonetti T, Grande AJ, da Rocha FR, et al. Whey protein and vitamin D supplementation in institutionalized older adults: A randomized trial. Nutr Health. 2023;29(1):129-138. doi:10.1177/02601060211060665
- 17Bell SJ, Potter PC. Milk whey-specific immune complexes in allergic and non-allergic subjects. Allergy. 1988;43(7):497-503. doi:10.1111/j.1398-9995.1988.tb01626.x
- 18Martin M, Hagemann D, Nguyen TT, et al. Plasma concentrations and ACE-inhibitory effects of tryptophan-containing peptides from whey protein hydrolysate in healthy volunteers. Eur J Nutr. 2020;59(3):1135-1147. doi:10.1007/s00394-019-01974-x
- 19Vasconcelos QDJS, Bachur TPR, Aragão GF. Whey protein supplementation and its potentially adverse effects on health: a systematic review. Appl Physiol Nutr Metab. 2021;46(1):27-33. doi:10.1139/apnm-2020-0370
- 20Rocha-Mendoza D, Kosmerl E, Krentz A, et al. Invited review: Acid whey trends and health benefits. J Dairy Sci. 2021;104(2):1262-1275. doi:10.3168/jds.2020-19038
- 21Baba WN, McClements DJ, Maqsood S. Whey protein-polyphenol conjugates and complexes: Production, characterization, and applications. Food Chem. 2021;365:130455. doi:10.1016/j.foodchem.2021.130455
- 22Zotta T, Solieri L, Iacumin L, Picozzi C, Gullo M. Valorization of cheese whey using microbial fermentations. Appl Microbiol Biotechnol. 2020;104(7):2749-2764. doi:10.1007/s00253-020-10408-2
- 23Bethencourt-Barbuzano E, González-Weller D, Paz-Montelongo S, et al. Whey Protein Dietary Supplements: Metal Exposure Assessment and Risk Characterization. Nutrients. 2023;15(16). doi:10.3390/nu15163543
- 24Thampy A, Palani Kumar MK, Serva Peddha M, Reddy M. The effectiveness of whey proteins in prevention and treatment of cancer: a review. Crit Rev Food Sci Nutr. 2024;64(8):2088-2104. doi:10.1080/10408398.2022.2121256
- 25Corrochano AR, Ferraretto A, Arranz E, et al. Bovine whey peptides transit the intestinal barrier to reduce oxidative stress in muscle cells. Food Chem. 2019;288:306-314. doi:10.1016/j.foodchem.2019.03.009
- 26Sajan AL, Pazheparambil Jerom J, Nair BR, et al. Alleviating effect of whey protein supplementation on oxidative stress in hypothyroidism. Food Funct. 2024;15(22):11158-11168. doi:10.1039/d4fo03186e
- 27Bourdeau T, Affolter M, Dupuis L, et al. Peptide Characterization and Functional Stability of a Partially Hydrolyzed Whey-Based Formula over Time. Nutrients. 2021;13(9). doi:10.3390/nu13093011