Sucralose properties, how it is made, and how the body handles it
What it found
Sucralose is a zero-calorie sweetener about 600 times sweeter than regular sugar.
It stays stable when heated, so it can be used in baked and fried foods.
What they found
Studies in people
Who uses it
People with diabetes or obesity take it as tablets. Drug makers also use it as a helper ingredient in medicines.
Studies in people and animals
How the body handles it
The authors gathered data on how sucralose is taken in, spread around, broken down, and cleared from the body. They also looked at its effects once inside.
Other findings
Sweetness and calories
Sucralose has no calories and is about 600 times as sweet as regular sugar. It is made from sugar by swapping three parts for chlorine atoms.
Use in cooking
Unlike some other artificial sweeteners, sucralose holds up under heat. That means it can go into baked and fried foods.
What the authors conclude
- They put together a full picture of sucralose, including how it is made, tested, and processed by the body.
- They also covered how it might relate to nutrition for people with obesity or diabetes.
How it was done
The authors wanted to gather a full profile of sucralose, covering how it is made, measured, and handled by the body. They also looked at its role for people with diabetes or obesity.
They gathered information on the physical traits, lab testing methods, and chemical makeup of sucralose. They also reviewed how the body absorbs, spreads, breaks down, and clears it. Both chemical and germ-based ways of making it were included.
What it can’t tell you
- We summarised it from the abstract only.
- This work gathers existing information rather than running new tests on people or animals. It cannot show whether sucralose causes any health effects on its own.
Who paid
- Authors work at
- Hail University, Saudi Arabia
The paper
- Title
- Sucralose
- Type
- ReviewThe authors read earlier studies and describe what they found. It isn’t a new study.
- Evidence
- Studies in people · animals · lab
- Summarised from
- Abstract only
- Cite
- AlDeeb OA, Mahgoub H, Foda NH (2013). Sucralose. Profiles of drug substances, excipients, and related methodology. doi:10.1016/B978-0-12-407691-4.00010-1PubMed 23668410DOI
Summary written 30 Sep 2026. Check it against the paper before it changes what you eat. How we summarise papers · Report an error