Review · Beneficial microbes · 2014Abstract only

Polydextrose fermentation in the large intestine and its effects

What it found

Polydextrose is slowly fermented by gut bacteria in the large intestine, and this has been shown to affect appetite and satiety in people and improve gut function.

What they found

Studies in people

Appetite and gut function

Polydextrose has been shown to affect appetite and fullness in people and to improve how the gut works.

Other findings

Structure and digestion

Polydextrose is a glucose polymer with a random, highly branched and complex structure. It resists digestion in the upper gut and is partly fermented by microbes in the large intestine.

Slow fermentation

Because its structure is complex, many different microbes are needed to break it down, and this happens slowly. This slow process produces moderate amounts of short chain fatty acids and gas.

Fermentation in distal colon

Fermentation products continue to be made in the far part of the colon, which is usually thought to have run out of fermentable materials.

Gut bacteria changes

Fermenting polydextrose changes the mix of bacteria in the colon.

What the authors conclude

  • They summarise the lab, animal and human studies on polydextrose fermentation in the large intestine.

How it was done

The authors wanted to summarise the lab, animal and human studies on how polydextrose is fermented in the large intestine.

What it can’t tell you

  • We summarised it from the abstract only.
  • This is a summary of other studies, so it cannot provide new data on polydextrose itself.
  • The human findings on appetite and gut function come from the studies reviewed, not from new experiments.

The paper

Title
The fermentation of polydextrose in the large intestine and its beneficial effects
Type
ReviewThe authors read earlier studies and describe what they found. It isn’t a new study.
Evidence
Studies in people
Summarised from
Abstract only
Cite
Röytiö H, Ouwehand AC (2014). The fermentation of polydextrose in the large intestine and its beneficial effects. Beneficial microbes. doi:10.3920/BM2013.0065PubMed 24736314DOI

Summary written 26 Sep 2026. Check it against the paper before it changes what you eat. How we summarise papers · Report an error