Study · Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment · 2017Abstract only

Cyclamate levels in tabletop sweeteners and daily intake risk

What it found

In lab tests, cyclamate levels in tabletop sweeteners ranged from 2.9% to 73.9%.

The authors say heavy use of one product could push someone past the acceptable daily intake.

What they found

Method performance

The method was specific and selective for cyclamate. Repeatability and intermediate precision were both within 3.3%, and recovery rates ranged from 92% to 108% across the different sweeteners.

Cyclamate levels varied

The amount of cyclamate in the tested sweeteners ranged widely, from 2.9% to 73.9%.

Possible daily intake exceedance

The authors say that heavy use of one of the analysed sweeteners could lead to going over the acceptable daily intake for cyclamate.

What the authors conclude

“The concentration of cyclamate in the samples varied significantly, from 2.9% to 73.9%, which demonstrated that a possible excessive consumption of one of the analysed sweeteners can lead to exceeding the acceptable daily intake for cyclamate.”
Sargaço B, Serra C, Vasco E, 2017

Also in their conclusions

  • They say the wide range of cyclamate levels shows that excessive consumption of one of the analysed sweeteners could lead to exceeding the acceptable daily intake for cyclamate.

How it was done

Cyclamate is widely used as an intense sweetener in the European Union. There is no maximum limit for cyclamate in tabletop sweeteners, and demand for these products is growing, so the authors wanted a reliable way to measure how much is in them and whether that could affect health.

They improved and checked a lab method for measuring cyclamate in tabletop sweeteners, based on European Standard EN 12857. They then used it on liquid, powder and tablet sweeteners.

What it can’t tell you

  • We summarised it from the abstract only.
  • This was a lab measurement of sweetener products, not a study of people eating them.
  • It cannot show what actually happens to health when someone exceeds the acceptable daily intake.

The paper

Title
Validation of an HPLC-DAD/UV method for the quantification of cyclamate in tabletop sweeteners: risk of exceeding the acceptable daily intake
Type
Study
Summarised from
Abstract only
Cite
Sargaço B, Serra C, Vasco E (2017). Validation of an HPLC-DAD/UV method for the quantification of cyclamate in tabletop sweeteners: risk of exceeding the acceptable daily intake. Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment. doi:10.1080/19440049.2017.1306756PubMed 28395647DOI

Summary written 26 Sep 2026. Check it against the paper before it changes what you eat. How we summarise papers · Report an error