Randomised trial · Journal of human nutrition and dietetics · 2020Abstract only

Soya lecithin in children with delayed soya allergy

What it found

In a small trial in children with a delayed gut reaction to soya, most children did not react to soya lecithin eaten in biscuits.

One child had a slight reaction to the lecithin.

What they found

Studies in people

Reactions reported

Parents reported reactions in six cases: five to the placebo and one to the soya lecithin. The authors say there was no statistical difference between the groups.

One slight reaction

One child with a non-IgE-mediated gastrointestinal allergy had a slight reaction to soya lecithin.

Children who took part

Twenty-two children were recruited, 16 boys, with a median age of 44 months (range 21 to 58 months). Only 20 completed the full study.

Other foods avoided

The median number of foods avoided in addition to soya was 3.

What the authors conclude

“Although single cases may react to soya lecithin, we suggest that soya lecithin should be included in children with this delayed allergy, unless they have a confirmed reaction to traces of soya within this emulsifier.”
Gholmie Y, Lozinsky AC, Godwin H, et al, 2020

Also in their conclusions

  • They suggest that soya lecithin should be included in children with this delayed allergy, unless they have a confirmed reaction to traces of soya within this emulsifier.
  • They note that although single cases may react to soya lecithin, one child in this study had a slight reaction.

How it was done

Soya lecithin is used in many foods children eat. Children with delayed allergies who already avoid milk and soya would have a much more limited diet if they also had to avoid soya lecithin.

Twenty-two children aged 8 months to 5 years with confirmed non-IgE-mediated gastrointestinal soya allergy took part. They were randomly given either soya lecithin (1.5 g per day) or a placebo in a biscuit for 1 week, then after a 1-week washout switched to the other for 1 week. Parents recorded symptoms before the study and at the end of each week.

What it can’t tell you

  • We summarised it from the abstract only.
  • This was a small trial with 20 children completing it, so the results may not apply to all children with this allergy.
  • The trial lasted only 1 week for each period, so it cannot show what happens over longer periods.

The paper

Title
Tolerance of soya lecithin in children with non-immunoglobulin E-mediated soya allergy: a randomised, double-blind, cross-over trial
Type
Randomised controlled trial
Evidence
Studies in people
Summarised from
Abstract only
Cite
Gholmie Y, Lozinsky AC, Godwin H, et al (2020). Tolerance of soya lecithin in children with non-immunoglobulin E-mediated soya allergy: a randomised, double-blind, cross-over trial. Journal of human nutrition and dietetics. doi:10.1111/jhn.12708PubMed 31603281DOI

Summary written 26 Sep 2026. Check it against the paper before it changes what you eat. How we summarise papers · Report an error