Randomised trial · Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme · 2021Abstract only

Beetroot juice and blood vessel function in HIV

What it found

Drinking nitrate-rich beetroot juice improved a measure of blood vessel function in both healthy people and people with HIV.

The improvement was seen 120 minutes after drinking it.

What they found

Studies in people

Blood vessel function at start

Before any drink, the healthy group had better flow-mediated dilation than the HIV group in both sessions.

Beetroot juice improved dilation

Flow-mediated dilation improved 120 minutes after beetroot juice in both the HIV and healthy groups.

Placebo had no effect

There was no change in flow-mediated dilation after the placebo drink in either group.

Pulse wave velocity unchanged

Pulse wave velocity showed no differences between groups, time points, or drinks.

What the authors conclude

“Our findings showed that nitrate-rich BJ ingestion acutely improved vascular function in healthy and HIV-infected patients.”
Nogueira Soares R, Machado-Santos AP, Barros-Santos E, Vieira De Oliveira G, Murias JM, Alvares TS, 2021

Also in their conclusions

  • They conclude that drinking nitrate-rich beetroot juice quickly improved blood vessel function in both healthy people and people with HIV.
  • They state that this is the first time beetroot juice has been shown to acutely improve endothelial function in HIV-infected patients.

How it was done

HIV is linked to lower nitric oxide availability and poorer blood vessel function. Nitrate-rich beetroot juice has been shown to quickly raise nitric oxide and improve blood vessel function in healthy people and those at high risk of heart disease.

Thirteen people with HIV (average age 36) and 18 healthy people (average age 27) had blood vessel tests before and 120 minutes after drinking beetroot juice or a placebo.

What it can’t tell you

  • We summarised it from the abstract only.
  • This trial only looked at one dose and measured effects up to 120 minutes later, so it cannot show what happens with longer use.
  • The study was small, so the results may not apply to all people with HIV or all healthy people.

The paper

Title
Acute supplementation with beetroot juice improves endothelial function in HIV-infected individuals
Type
Randomised controlled trial
Evidence
Studies in people
Summarised from
Abstract only
Cite
Nogueira Soares R, Machado-Santos AP, Barros-Santos E, Vieira De Oliveira G, Murias JM, Alvares TS (2021). Acute supplementation with beetroot juice improves endothelial function in HIV-infected individuals. Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme. doi:10.1139/apnm-2020-0498PubMed 32866396DOI

Summary written 26 Sep 2026. Check it against the paper before it changes what you eat. How we summarise papers · Report an error