Milk protein concentrate with a weight-loss diet in obese women
What it found
This is a plan for a trial in 44 obese women to see whether 30 grams of milk protein concentrate a day, alongside a weight-loss diet, changes metabolic measures, appetite hormones and body composition.
The results are not yet available.
What they found
Studies in people
Who is in the trial
The trial plans to recruit 44 premenopausal obese women with a BMI of 30 to 40. They must not be pregnant or breastfeeding, and must not have food allergies or certain health conditions.
Outcomes measured
The main outcomes are leptin, adiponectin, waist circumference, BMI and body composition. Other measures include fasting glucose and insulin, blood fats, insulin resistance and appetite.
Background from people
One study found that giving milk protein concentrate directly into the small intestine improved the blood sugar and food intake effects of a diabetes drug. The authors say this supports the idea that dairy protein may help as an add-on to such drugs.
Animal and lab studies
Background from animals
A study in obese rats found that milk protein concentrate reduced body weight and fat accumulation more than casein or whey protein alone. This may be because it is digested more slowly and keeps you feeling fuller.
Other findings
What is being tested
The trial will test 30 grams of milk protein concentrate daily for 8 weeks, added to a weight-loss diet. The powder provides 105 kcal, 0.4 g fat, 6 g carbohydrate and 20 g protein per sachet.
What the authors conclude
- They aim to find out if 30 grams of milk protein concentrate alongside a weight-loss diet improves metabolic parameters, appetite hormones and body composition in obese women.
- They say the results will help understand the effectiveness of milk protein concentrate with a weight-loss diet compared with a control group.
- They add that the findings may help obese women lose weight and improve their heart and metabolic health.
How it was done
The authors say no study has yet looked at milk protein concentrate together with a weight-loss diet in obese women. They want to know if it improves metabolic measures, appetite hormones and body composition.
They planned an 8-week randomised controlled trial in 44 premenopausal obese women aged 18 or older, split into two groups of 22. Both groups follow a diet with 800 kcal less than their estimated needs; one group also takes a 30-gram milk protein concentrate sachet each morning.
What it can’t tell you
- This is a study protocol, so no results are available yet.
- The trial will only include women, so the findings may not apply to men.
- The trial will not measure other appetite-related hormones or gut hormones because of funding limits.
Who paid
- Conflicts
- Competing interests: None declared.
- Authors work at
- Ahvaz Jundishapur University of Medical Sciences, Iran; Deakin University, Australia; Khalkhal University of Medical Sciences, Iran
The paper
- Title
- Effects of milk protein concentrate supplementation on metabolic parameters, adipocytokines and body composition in obese women under weight-loss diet: study protocol for a randomised controlled trial
- Type
- Study
- Evidence
- Studies in people · animals · lab
- Summarised from
- Full text
- Cite
- Haidari F, Elahikhah M, Shariful Islam SM, Mohammadshahi M, Shahbazian H, Aghamohammadi V (2022). Effects of milk protein concentrate supplementation on metabolic parameters, adipocytokines and body composition in obese women under weight-loss diet: study protocol for a randomised controlled trial. BMJ open. doi:10.1136/bmjopen-2022-064727Free full textPubMed 36202586DOI
Summary written 26 Sep 2026. Check it against the paper before it changes what you eat. How we summarise papers · Report an error