Thiamin intake and high uric acid in US adults
What it found
In US adults, men who ate more thiamin had lower odds of high uric acid, but women did not.
This was a survey, so it cannot show cause and effect.
What they found
Studies in people
High uric acid in men
Men who took in more vitamin B1 had lower odds of high uric acid. Compared with the lowest intake group, the odds fell as intake rose, and the trend was statistically significant.
No link in women
In women, vitamin B1 intake was not linked to high uric acid. The trend test was not statistically significant.
Uric acid levels in men
In men, higher vitamin B1 intake went with lower blood uric acid levels. This was shown by a smoothed curve.
Uric acid levels in women
In women, there was no significant link between vitamin B1 intake and blood uric acid levels.
Prevalence of high uric acid
The prevalence of high uric acid was 18.90% overall. It was 20.15% in men and 17.79% in women.
Subgroups in men
The link in men was seen in non-Hispanic White men and in middle-aged men (42 to 60 years old). No link was found in groups based on BMI or alcohol consumption.
What the authors conclude
“Our study suggests that that dietary vitamin B1 intake is negatively associated with hyperuricemia in men among US adults after adjusting for major confounders.”
Also in their conclusions
- They say dietary vitamin B1 intake is negatively associated with high uric acid in men among US adults after adjusting for major confounders.
- They call for large prospective cohort studies to support their findings.
How it was done
The authors say studies on whether dietary vitamin B1 intake is linked to high uric acid are scarce. They wanted to look at this link in a large, nationally representative sample of US adults.
They used data from 5750 adults aged 20 and over in the National Health and Nutrition Examination Survey from March 2017 to March 2020. Vitamin B1 intake was estimated from 24-hour dietary recall interviews, and blood uric acid was measured.
What it can’t tell you
- This was a cross-sectional study, so it cannot show that vitamin B1 intake causes lower uric acid.
- Dietary intake was estimated from 24-hour recalls, which may not reflect long-term habits.
- The study cannot rule out other unmeasured factors that might explain the link.
Who paid
- Conflicts
- The authors declare no competing interests.
- Authors work at
- Jining Medical University, China; Affiliated Hospital of Jining Medical University, China; Jining First People's Hospital, China
The paper
- Title
- Association between vitamin B1 intake and hyperuricemia in adults
- Type
- Study
- Evidence
- Studies in people
- Summarised from
- Full text
- Cite
- Li YM, Xu XH, Xu XF, et al (2024). Association between vitamin B1 intake and hyperuricemia in adults. Scientific reports. doi:10.1038/s41598-024-66384-4Free full textPubMed 39013961DOI
Summary written 26 Sep 2026. Check it against the paper before it changes what you eat. How we summarise papers · Report an error