Coffee, caffeine and functional dyspepsia in Iranian adults
What it found
In a large group of Iranian adults, coffee and caffeine intake was not linked to functional dyspepsia or its symptoms.
The study was in people.
What they found
Studies in people
Functional dyspepsia
Coffee intake was not significantly associated with functional dyspepsia. The prevalence of functional dyspepsia in the group was 14.5%.
Caffeine and dyspepsia
Caffeine intake was not significantly associated with functional dyspepsia.
Symptoms
Coffee and caffeine intake were not significantly associated with early satiation, post-prandial fullness, or epigastric pain.
By gender and BMI
When the researchers looked separately at men and women, and at normal-weight and overweight people, they still found no significant links.
Tea and dyspepsia
Tea consumption was also not significantly associated with functional dyspepsia.
What the authors conclude
“In conclusion, we found no significant association between coffee and caffeine consumption with odds of FD and its symptoms.”
Also in their conclusions
- They found no significant association between coffee and caffeine consumption and odds of functional dyspepsia and its symptoms.
- They say further research in other populations with high coffee consumption is needed.
- They suggest that investigating the impact of discontinuing coffee and caffeine consumption on functional dyspepsia symptoms through an interventional study could help clarify the effects.
How it was done
Coffee can stimulate stomach acid and may affect digestion, but few studies have looked at whether it is linked to functional dyspepsia. The authors wanted to examine this in a population with high rates of the condition.
They studied 3362 adults aged 18 to 55 in Iran. Participants filled out a food frequency questionnaire and a questionnaire about gut symptoms. The researchers compared coffee and caffeine intake with the presence of functional dyspepsia.
What it can’t tell you
- This was a cross-sectional study, so it cannot show whether coffee or caffeine causes functional dyspepsia or its symptoms.
- Coffee and caffeine intake were assessed by a food frequency questionnaire, which may lead to some misclassification.
- The study did not have information on the type of coffee or how it was prepared, which may affect the findings.
Who paid
- Conflicts
- Declarations. Competing interests: The authors declare no competing interests. Ethical approval and consent participants: The study protocol was ethically approved by the Regional Bioethics Committee of Isfahan University of Medical Sciences. All participants provided written informed consent forms. All methods were carried out in accordance with relevant guideline and regulations.
- Authors work at
- Maragheh University of Medical Sciences, Iran; Ilam University of Medical Sciences, Iran; University of Alberta, Canada
The paper
- Title
- Association between coffee and caffeine intake and functional dyspepsia
- Type
- Study
- Evidence
- Studies in people
- Summarised from
- Full text
- Cite
- Koochakpoor G, Salari-Moghaddam A, Keshteli AH, Esmaillzadeh A, Adibi P (2024). Association between coffee and caffeine intake and functional dyspepsia. Scientific reports. doi:10.1038/s41598-024-81670-xFree full textPubMed 39738317DOI
Summary written 26 Sep 2026. Check it against the paper before it changes what you eat. How we summarise papers · Report an error