Study · Epidemiologia e servicos de saude · 2026Conflicts declared

Ferrous sulfate and folic acid use in pregnant people

What it found

In 428 pregnant people in Criciúma, Brazil, 97.4% received ferrous sulfate and 93.7% received folic acid during pregnancy.

Use was higher in older people and those with more prenatal visits.

What they found

Studies in people

How many got supplements

Of the 428 pregnant people, 97.4% received ferrous sulfate and 93.7% received folic acid at some point during pregnancy.

Ferrous sulfate and age

Ferrous sulfate use rose with age, reaching 100% among those aged 30 or older. Those aged 30 or older had 6% higher use than those aged 18 to 19.

Ferrous sulfate and alcohol

People who drank alcohol during pregnancy had 4% higher ferrous sulfate use than those who did not.

Folic acid and visits

People with six or more prenatal visits had 10% higher folic acid use than those with fewer than six visits. Use was 95.6% versus 86.2%.

Smoking and supplements

Smokers had lower use of both supplements: 89.5% for ferrous sulfate versus 97.8% in non-smokers, and 78.9% for folic acid versus 94.4% in non-smokers.

What the authors conclude

“The results indicate high iron and folic acid supplementation among pregnant people in Primary Health Care.”
Campos-Rosa J, Puchivailo RAC, Schäfer AA, Meller FO, Miranda VIA, 2026

Also in their conclusions

  • They say the results show high ferrous sulfate and folic acid supplementation among pregnant people in primary care, suggesting the National Iron Supplementation Program is working.
  • They advise that identifying factors linked to supplementation, such as age, alcohol use and number of prenatal visits, can guide more targeted strategies by health management.
  • They state that continuous monitoring and improvement of the supplementation programme are essential so all pregnant people have adequate access to these nutrients.

How it was done

Iron and folic acid needs rise in pregnancy and can be hard to meet through diet alone. The authors wanted to check how many pregnant people in local primary care actually received these supplements and what factors were linked to their use.

They interviewed 428 pregnant people aged 18 or over in their third trimester who were getting prenatal care at 48 health centres in Criciúma, Brazil, between April and December 2022. Supplement use was read from each person's prenatal booklet.

What it can’t tell you

  • This was a cross-sectional study, so it can show links but not cause and effect.
  • The prenatal booklet records only whether supplements were prescribed, not how much was taken or how regularly.
  • The findings come from one city in Brazil and may not apply to other places.

The paper

Title
Ferrous Sulfate and Folic Acid Supplementation in Pregnant People in Primary Health Care: a Cross-Sectional Study, Criciúma, 2022
Type
Study
Evidence
Studies in people
Summarised from
Full text
Cite
Campos-Rosa J, Puchivailo RAC, Schäfer AA, Meller FO, Miranda VIA (2026). Ferrous Sulfate and Folic Acid Supplementation in Pregnant People in Primary Health Care: a Cross-Sectional Study, Criciúma, 2022. Epidemiologia e servicos de saude. doi:10.1590/S2237-96222026v35e20240377.enFree full textPubMed 42718097DOI

Summary written 26 Sep 2026. Check it against the paper before it changes what you eat. How we summarise papers · Report an error