Study · Archives of disease in childhood · 1970Abstract only

Gluten intolerance in one infant after a gut infection

What it found

One infant who could not handle gluten after a gut infection recovered fully on a gluten-free diet.

His gut lining returned to normal and stayed normal when he ate gluten again.

What they found

Studies in people

Gut damage after infection

A biopsy of the infant's small bowel showed severe flattening of the gut lining. This happened two months after a salmonella infection.

Response to gluten-free diet

The infant improved quickly once he started eating no gluten. He stayed on this diet for one year.

Gut healed on normal diet

After a year without gluten, a second biopsy showed his gut lining was normal. A third biopsy 16 months later, while eating a normal diet, was still normal.

What the authors conclude

  • They suggest the infant had a temporary intolerance to gluten that followed his gut infection.
  • They advise that improving on a gluten-free diet does not always mean someone has coeliac disease.

How it was done

The authors wanted to describe an infant who developed severe gut damage and swelling after a salmonella infection. They explored whether his reaction to gluten was permanent or temporary.

They followed one infant who had swelling from low protein two months after a salmonella gut infection. He ate a gluten-free diet for one year, then returned to a normal diet. Doctors took three small bowel biopsies over about two years.

What it can’t tell you

  • We summarised it from the abstract only.
  • This report follows only one infant. It cannot show how often temporary gluten problems happen after gut infections in other children or adults.

The paper

Title
Transient gluten intolerance
Type
Study
Evidence
Studies in people
Summarised from
Abstract only
Cite
Walker-Smith J (1970). Transient gluten intolerance. Archives of disease in childhood. doi:10.1136/adc.45.242.523PubMed 5506937DOI

Summary written 30 Sep 2026. Check it against the paper before it changes what you eat. How we summarise papers · Report an error