E160aColour

Carotene

What the research shows

Mostly no concerns

most studies in people found no harm or a benefit

Used in food as a colour.

  • May not be vegan
  • May not be vegetarian
  • EU permitted

What research says

Studies in people

  • Benefit

    Breast cancer risk1

    Studies suggest carotene in the diet may be linked to a lower risk of breast cancer.

  • Benefit

    Risk of dying2

    In studies of healthy adults, higher beta-carotene in diet or blood was linked to lower death risk.

  • Benefit

    Eye health and cataracts3

    Eating more carotene and vitamin A may be linked to a lower risk of cataracts, but this is not certain.

  • Benefit

    Sunburn protection from food4

    In people, eating carotene-rich foods like tomatoes for several weeks made sun-reddened skin less red.

  • Open question

    Brain aging and memory5

    In older people, low carotene levels in the blood went with Alzheimer's, but we don't know if carotene prevents it.

  • Concern

    Lung cancer risk7

    In a Finnish trial, male smokers taking beta-carotene supplements had more lung cancer, not less.

  • Concern

    Cancer risk from supplements8

    Carotene in food seems helpful, but high-dose pills raised cancer cases in smokers and asbestos workers.

  • Benefit

    Memory and thinking skills9

    Carotene eaten in food or taken with other vitamins may help keep thinking sharp, but scientists do not yet know for sure.

  • Benefit

    Lung health in cystic fibrosis10

    In people with cystic fibrosis, beta-carotene supplements may mean fewer days on antibiotics for lung flare-ups, but the evidence is weak.

  • Concern

    Lung cancer risk in smokers11

    Smokers who took high doses of beta-carotene got lung cancer more often in some studies.

  • Open question

    Cancer risk and diet12

    In people, carotene supplements are being tested in trials, but whether they lower cancer risk is not yet known.

  • Benefit

    Fat and absorption13

    Eating fat with carotene helps the body take in more, but people vary a lot.

  • Open question

    Skin colour changes14

    In people taking carotene pills, some skin turned yellow-orange, and some blood antioxidant levels changed.

  • Benefit

    Anxiety in midlife women15

    In US midlife women, eating more beta-carotene was linked to less anxiety in early perimenopause, but not before it.

  • Benefit

    Oxidative stress markers17

    In healthy people, carotene supplements raised blood carotene levels, but only the 40 mg dose lowered one oxidative stress marker.

Animal and lab studies only

  • Benefit

    Artery plaque build-up19

    In mice, carotene helped clear fatty plaque from arteries, the authors say.

  • Benefit

    Skin rash in mice21

    In mice, eating carotene made skin rash symptoms milder than in mice that did not get it.

  • Benefit

    Vitamin A from food22

    Bread made with orange sweet potato contains carotene the body can turn into vitamin A.

Study type not stated

  • Open question

    Gut bacteria and health18

    Reviews of studies suggest carotene, vitamin C and vitamin E may change gut bacteria, but this link to health is unproven.

How it’s made and used

The signal at the top counts the findings in people and in animal and lab studies. A concern in studies of people outranks animal and lab studies, and “No concerns” needs at least one finding in people. When most findings in people point one way, the page leans that way (“Mostly”), and every finding is still shown. Findings whose study type is not stated are shown but not counted. This page is a reference, not medical advice. It describes what regulators and published research say. Talk to a doctor or dietitian about your own diet.

What expert reviews concluded

Expert panels that weigh all the research. Shown for context: the signal at the top does not count them.

Regulatory status

Checked Sep 2026

Status reflects the named register on the date checked. It is not a safety rating. A country appears here once we've found this ingredient on its official list.

How we check

Products

The 6 most-scanned of 12,246 products on Open Food Facts that list carotene.

  • Cappy PULPY Coca cola · 1 L 9 additives
  • مارغرين المائدة Lilia · 400 g 7 additives
  • BUTTERY FLORA · 450 g 2 additives
  • High Protein Drink Gusto Vaniglia Milbona · 350 g 2 additives
  • Fanta 0,5 Fanta · 500 ml 4 additives
  • High Protein Pudding Chocolate & Caramel Flavour Milbona · 150 g 6 additives

References

  1. 1Peraita-Costa I, Carrillo Garcia P, Morales-Suárez-Varela M. Is There an Association between β-Carotene and Breast Cancer? A Systematic Review on Breast Cancer Risk. Nutr Cancer. 2022;74(1):39-54. doi:10.1080/01635581.2020.1865422
  2. 2Zhao LG, Zhang QL, Zheng JL, et al. Dietary, circulating beta-carotene and risk of all-cause mortality: a meta-analysis from prospective studies. Sci Rep. 2016;6:26983. doi:10.1038/srep26983
  3. 3Wang A, Han J, Jiang Y, Zhang D. Association of vitamin A and β-carotene with risk for age-related cataract: a meta-analysis. Nutrition. 2014;30(10):1113-21. doi:10.1016/j.nut.2014.02.025
  4. 4Stahl W, Sies H. β-Carotene and other carotenoids in protection from sunlight. Am J Clin Nutr. 2012;96(5):1179S-84S. doi:10.3945/ajcn.112.034819
  5. 5Boccardi V, Arosio B, Cari L, et al. Beta-carotene, telomerase activity and Alzheimer's disease in old age subjects. Eur J Nutr. 2020;59(1):119-126. doi:10.1007/s00394-019-01892-y
  6. 6Haftel L, Berkovich Z, Reifen R. Elevated milk β-carotene and lycopene after carrot and tomato paste supplementation. Nutrition. 2015;31(3):443-5. doi:10.1016/j.nut.2014.10.009
  7. 7Buring JE, Hennekens CH. beta-carotene and cancer chemoprevention. J Cell Biochem Suppl. 1995;22:226-30. doi:10.1002/jcb.240590828
  8. 8Paiva SA, Russell RM. Beta-carotene and other carotenoids as antioxidants. J Am Coll Nutr. 1999;18(5):426-33. doi:10.1080/07315724.1999.10718880
  9. 9Abrego-Guandique DM, Bonet ML, Caroleo MC, et al. The Effect of Beta-Carotene on Cognitive Function: A Systematic Review. Brain Sci. 2023;13(10). doi:10.3390/brainsci13101468
  10. 10de Vries JJ, Chang AB, Bonifant CM, Shevill E, Marchant JM. Vitamin A and beta (β)-carotene supplementation for cystic fibrosis. Cochrane Database Syst Rev. 2018;8(8):CD006751. doi:10.1002/14651858.CD006751.pub5
  11. 11Siems W, Wiswedel I, Salerno C, et al. Beta-carotene breakdown products may impair mitochondrial functions--potential side effects of high-dose beta-carotene supplementation. J Nutr Biochem. 2005;16(7):385-97. doi:10.1016/j.jnutbio.2005.01.009
  12. 12Bendich A. The safety of beta-carotene. Nutr Cancer. 1988;11(4):207-14. doi:10.1080/01635588809513989
  13. 13Dimitrov NV, Meyer C, Ullrey DE, et al. Bioavailability of beta-carotene in humans. Am J Clin Nutr. 1988;48(2):298-304. doi:10.1093/ajcn/48.2.298
  14. 14McGill CR, Green NR, Meadows MC, Gropper SS. Beta-carotene supplementation decreases leukocyte superoxide dismutase activity and serum glutathione peroxidase concentration in humans. J Nutr Biochem. 2003;14(11):656-62. doi:10.1016/j.jnutbio.2003.08.003
  15. 15Li D, Wu Q, Tong Y, Zheng H, Li Y. Dietary beta-carotene intake is inversely associated with anxiety in US midlife women. J Affect Disord. 2021;287:96-100. doi:10.1016/j.jad.2021.03.021
  16. 16Prince MR, Frisoli JK. Beta-carotene accumulation in serum and skin. Am J Clin Nutr. 1993;57(2):175-81. doi:10.1093/ajcn/57.2.175
  17. 17Elmadfa I, Rust P, Majchrzak D, et al. Effects of beta-carotene supplementation on free radical mechanism in healthy adult subjects. Int J Vitam Nutr Res. 2004;74(2):147-52. doi:10.1024/0300-9831.74.2.147
  18. 18Li XY, Meng L, Shen L, Ji HF. Regulation of gut microbiota by vitamin C, vitamin E and β-carotene. Food Res Int. 2023;169:112749. doi:10.1016/j.foodres.2023.112749
  19. 19Pinos I, Coronel J, Albakri A, et al. β-Carotene accelerates the resolution of atherosclerosis in mice. Elife. 2024;12. doi:10.7554/eLife.87430
  20. 20Xiao F, Zhang L, Xie H, et al. The construction of Moringa oleifera seed protein emulsion: in vitro digestibility and delivery of β-carotene. J Sci Food Agric. 2024;104(13):7953-7964. doi:10.1002/jsfa.13626
  21. 21Hiragun M, Hiragun T, Oseto I, et al. Oral administration of β-carotene or lycopene prevents atopic dermatitis-like dermatitis in HR-1 mice. J Dermatol. 2016;43(10):1188-1192. doi:10.1111/1346-8138.13350
  22. 22Mbogo D, Muzhingi T, Janaswamy S. Starch digestibility and β-carotene bioaccessibility in the orange- fleshed sweet potato puree-wheat bread. J Food Sci. 2021;86(3):901-906. doi:10.1111/1750-3841.15620