Chili pepper
What the research shows
Concerning
in animal and lab studies only
A spicy fruit used as a spice.
It adds spicy heat and flavor to many dishes.1
What research says
Studies in people
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Benefit
Weight loss2
In people, eating chili pepper helped with weight loss in studies lasting up to 12 weeks.
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Benefit
Risk of dying3
People who ate chili pepper often had a lower risk of dying from any cause, heart disease or cancer.
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Benefit
Mouth burn from spicy food4
In people, milk proteins lowered the mouth burn from chili pepper's capsaicin, and casein worked better than whey.
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Open question
Aortic dissection risk7
People with aortic dissection ate less spicy food and had less capsaicin in their blood than people at risk.
Animal and lab studies only
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Benefit
Metabolic syndrome13
In lab and animal studies, low-dose capsaicin from chili pepper improved insulin sensitivity and decreased body fat.
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Concern
Gut inflammation and stature14
In animal studies, a chili pepper-rich diet was linked to gut inflammation and signals tied to short stature in children.
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Benefit
Gut bacteria health15
In lab studies, chili pepper's capsaicin made gut bacteria more varied and raised butanoic acid levels.
Study type not stated
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Benefit
Gut health11
Eating chili pepper in normal amounts may help the gut, though scientists are still studying how capsaicin works.
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Benefit
Memory and thinking in Alzheimer's12
In people, eating more chili pepper was linked to better thinking scores, and in mice it eased Alzheimer's-like memory problems.
How it’s made and used
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Exercise performance5
In men, capsaicin before lifting let them move more weight and feel less tired.
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Running performance6
In active men, capsaicin before a 1,500m run slightly improved times and made the effort feel easier.
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Mouth feel of food8
In people, chili pepper's heat made it harder to tell how thick a soup was.
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Mouth burn while eating9
In people eating chicken tikka masala, the burn from chili pepper's capsaicin rose then leveled off, while liking dropped.
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Brain response to spicy food10
People who often eat spicy food found chili pepper more pleasant, and their brains responded differently than those who rarely ate it.
The signal at the top counts the findings in people and in animal and lab studies. A concern in studies of people outranks animal and lab studies, and “No concerns” needs at least one finding in people. When most findings in people point one way, the page leans that way (“Mostly”), and every finding is still shown. Findings whose study type is not stated are shown but not counted. This page is a reference, not medical advice. It describes what regulators and published research say. Talk to a doctor or dietitian about your own diet.
Products
The 6 most-scanned of 29,624 products on Open Food Facts that list chili pepper.
- Sriracha Sauce Flying Goose Brand · 455 ml 5 additives
- Tyrrell's Sweet Chilli & Red Pepper Tyrrell’s · 30 g x5 (150 g) 1 additive
- Sardines huile d'olives et piment Parmentier · 135 g 0 additives
- Buldak Spicy Ramen Samyang · 4.94 oz (140 g) 14 additives
- Beef Flavour Yum Yum · 60 g 8 additives
- CRISPY CHILLI OIL LAOGANMA · 210 g 1 additive
References
- 1Chili pepper. Wikipedia. Accessed September 26, 2026. CC BY-SA 4.0.
- 2Varghese S, Kubatka P, Rodrigo L, et al. Chili pepper as a body weight-loss food. Int J Food Sci Nutr. 2017;68(4):392-401. doi:10.1080/09637486.2016.1258044
- 3Yang L, Sun J, Zhao M, Xi B. Chili pepper intake and all-cause and disease-specific mortality. Int J Vitam Nutr Res. 2023;93(4):378-384. doi:10.1024/0300-9831/a000746
- 4Farah BA, Hayes JE, Coupland JN. The effect of dairy proteins on the oral burn of capsaicin. J Food Sci. 2023;88(S1):147-157. doi:10.1111/1750-3841.16400
- 5Conrado de Freitas M, Cholewa JM, Freire RV, et al. Acute Capsaicin Supplementation Improves Resistance Training Performance in Trained Men. J Strength Cond Res. 2018;32(8):2227-2232. doi:10.1519/JSC.0000000000002109
- 6de Freitas MC, Cholewa JM, Gobbo LA, de Oliveira JVNS, Lira FS, Rossi FE. Acute Capsaicin Supplementation Improves 1,500-m Running Time-Trial Performance and Rate of Perceived Exertion in Physically Active Adults. J Strength Cond Res. 2018;32(2):572-577. doi:10.1519/JSC.0000000000002329
- 7Lan W, Yang H, Liu W, et al. Dietary capsaicin attenuates aortic dissection by inhibiting M1 macrophage polarisation and modulating the gut microbiota. Phytomedicine. 2026;156:158269. doi:10.1016/j.phymed.2026.158269
- 8Lyu C, Schijvens D, Hayes JE, Stieger M. Capsaicin burn increases thickness discrimination thresholds independently of chronic chili intake. Food Res Int. 2021;149:110702. doi:10.1016/j.foodres.2021.110702
- 9Cunningham PM, Hayes JE. Minimal sensitization to repeated capsaicin exposure during consumption of a real food. Physiol Behav. 2025;301:115066. doi:10.1016/j.physbeh.2025.115066
- 10Zhou L, Ma Y, Hummel T, Han P. Differential neural correlates of oral capsaicin pleasantness in habitual and non-habitual spicy eaters. Neuroimage. 2025;323:121601. doi:10.1016/j.neuroimage.2025.121601
- 11Xiang Y, Xu X, Zhang T, et al. Beneficial effects of dietary capsaicin in gastrointestinal health and disease. Exp Cell Res. 2022;417(2):113227. doi:10.1016/j.yexcr.2022.113227
- 12Li Y, Wang H, Zhang D, et al. Gut microbiota-dependent 24-hydroxycholesterol metabolism contributes to capsaicin-induced amelioration of Alzheimer's disease-like pathology in mice. Nat Commun. 2026;17(1). doi:10.1038/s41467-026-68937-9
- 13Panchal SK, Bliss E, Brown L. Capsaicin in Metabolic Syndrome. Nutrients. 2018;10(5). doi:10.3390/nu10050630
- 14Wang Y, Wu Z, Yuan J, et al. Capsaicin diet drives gut inflammation and exosomal miR-17-3p elevation in idiopathic short stature. Nat Commun. 2025;17(1):1123. doi:10.1038/s41467-025-67883-2
- 15Mahalak KK, Bobokalonov J, Firrman J, et al. Analysis of the Ability of Capsaicin to Modulate the Human Gut Microbiota In Vitro. Nutrients. 2022;14(6). doi:10.3390/nu14061283