E968Humectant · Sweetener
Erythritol
What the research shows
Mostly no concerns
most studies in people found no harm or a benefit
A sweetener made from corn using enzymes and fermentation.
It is used as a food additive and sugar substitute.1
- Vegan
- Vegetarian
- EU permitted
What research says
Studies in people
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Benefit
Tooth decay and blood sugar2
Erythritol is a sweetener that may cut tooth decay and does not raise blood sugar.
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Benefit
Blood sugar control3
Erythritol is a sweetener studied for helping keep blood sugar levels steady in people and animals.
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Concern
Gut side effects4
Eating a lot of erythritol can cause diarrhoea, and some people may eat more than the level experts consider safe.
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Concern
Blood clotting risk5
In healthy people, eating erythritol made their blood platelets stickier, which may raise clotting risk.
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Open question
Heart and diabetes risk6
Erythritol is a sweetener, and high levels in the blood may predict future diabetes and weight gain.
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Open question
How the body handles sweeteners8
In people, erythritol is taken up by the body and turned into erythronate, but what that means for health is still unknown.
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Benefit
Tooth decay in children9
In schoolchildren, eating erythritol candies daily meant fewer holes in their teeth than xylitol or sorbitol candies.
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No harm found
Blood sugar and insulin10
Erythritol did not change blood sugar or insulin levels in people who ate it.
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Open question
Stroke risk11
A study linked genetically predicted erythritol levels to stroke, but this does not show that eating erythritol causes stroke.
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No harm found
Blood sugar and digestion12
Erythritol did not change blood sugar or insulin, and people's stomachs handled it as well as sugar.
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Benefit
Tooth decay risk13
Teens who used erythritol had less plaque and fewer decay-causing bacteria in their mouths.
Animal and lab studies only
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Concern
Blood vessel health in the brain16
In lab studies, erythritol raised oxidative stress and lowered nitric oxide in human brain blood vessel cells.
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Benefit
Blood sugar after meals17
In animal studies, erythritol lowered blood sugar after eating in diabetic mice.
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Benefit
Sweetener and gut health18
Erythritol helped gut bacteria from people make more butyrate.
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No harm found
Gut bacteria and gas19
In lab studies, erythritol was not broken down by gut bacteria, so it likely makes no gas or energy.
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Benefit
Blood vessel lining in diabetes20
In lab studies, erythritol protected blood vessel lining cells from dying when glucose was high.
Study type not stated
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Open question
Heart and blood clotting15
Scientists do not yet know whether eating erythritol raises the risk of heart problems.
Single cases of misuse or overdose
One person or one incident, such as an accidental overdose or a mistake in a kitchen or factory. They are real, but a single case does not show what happens at normal amounts, so the signal does not count them.
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Allergic reaction to a sweetener14
A woman had a severe allergic reaction after drinking a diet beverage containing erythritol.
How it’s made and used
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Sweet drink cravings7
In people, drinks paired with erythritol ended up just as liked as those paired with sugar.
The signal at the top counts the findings in people and in animal and lab studies. A concern in studies of people outranks animal and lab studies, and “No concerns” needs at least one finding in people. When most findings in people point one way, the page leans that way (“Mostly”), and every finding is still shown. Findings whose study type is not stated are shown but not counted. This page is a reference, not medical advice. It describes what regulators and published research say. Talk to a doctor or dietitian about your own diet.
Regulatory status
Checked Sep 2026-
European Union Permitted EUR-Lex Reg. (EC) 1333/2008
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United Kingdom Permitted FSA retained EU law
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Canada Permitted Health Canada · Sweeteners
Status reflects the named register on the date checked. It is not a safety rating. A country appears here once we've found this ingredient on its official list.
How we checkProducts
The 6 most-scanned of 2,914 products on Open Food Facts that list erythritol.
- High Protein Joghurterzeugnis - Heidelbeere Milbona · 200 g 3 additives
- Yogur High Protein Coco Milbona · 200 g 2 additives
- Raspberry-Pomegranate Milk Product Milbona · 200 gram 3 additives
- Strawberry Milk Product Milbona · 200 g 2 additives
- Protein Chocolate Flavour Pudding Arla · 200 g 5 additives
- nut granola Blueberry Cinnamon nutrail · 22 oz 1 additive
References
- 1Erythritol. Wikipedia. Accessed September 26, 2026. CC BY-SA 4.0.
- 2de Cock P. Erythritol Functional Roles in Oral-Systemic Health. Adv Dent Res. 2018;29(1):104-109. doi:10.1177/0022034517736499
- 3Wölnerhanssen BK, Meyer-Gerspach AC, Beglinger C, Islam MS. Metabolic effects of the natural sweeteners xylitol and erythritol: A comprehensive review. Crit Rev Food Sci Nutr. 2020;60(12):1986-1998. doi:10.1080/10408398.2019.1623757
- 4Younes M, Aquilina G, Castle L, et al. Re-evaluation of erythritol (E 968) as a food additive. EFSA J. 2023;21(12):e8430. doi:10.2903/j.efsa.2023.8430
- 5Witkowski M, Wilcox J, Province V, et al. Ingestion of the Non-Nutritive Sweetener Erythritol, but Not Glucose, Enhances Platelet Reactivity and Thrombosis Potential in Healthy Volunteers-Brief Report. Arterioscler Thromb Vasc Biol. 2024;44(9):2136-2141. doi:10.1161/ATVBAHA.124.321019
- 6Ortiz SR, Field MS. Mammalian metabolism of erythritol: a predictive biomarker of metabolic dysfunction. Curr Opin Clin Nutr Metab Care. 2020;23(5):296-301. doi:10.1097/MCO.0000000000000665
- 7Flad E, Teysseire F, Budzinska A, et al. Erythritol, sucrose, and sucralose elicit similar reward responses after flavor preference learning in healthy humans. Physiol Behav. 2026;314:115394. doi:10.1016/j.physbeh.2026.115394
- 8Bordier V, Teysseire F, Senner F, et al. Absorption and Metabolism of the Natural Sweeteners Erythritol and Xylitol in Humans: A Dose-Ranging Study. Int J Mol Sci. 2022;23(17). doi:10.3390/ijms23179867
- 9Honkala S, Runnel R, Saag M, et al. Effect of erythritol and xylitol on dental caries prevention in children. Caries Res. 2014;48(5):482-90. doi:10.1159/000358399
- 10Bornet FR, Blayo A, Dauchy F, Slama G. Plasma and urine kinetics of erythritol after oral ingestion by healthy humans. Regul Toxicol Pharmacol. 1996;24(2 Pt 2):S280-5. doi:10.1006/rtph.1996.0109
- 11Zhong A, Yu F, Xia C, et al. Risk of Erythritol-Associated Ischemic Stroke: Integrated Genetic, Transcriptomic, and Machine Learning Evidence. Int J Mol Sci. 2026;27(17). doi:10.3390/ijms27177811
- 12Bornet FR, Blayo A, Dauchy F, Slama G. Gastrointestinal response and plasma and urine determinations in human subjects given erythritol. Regul Toxicol Pharmacol. 1996;24(2 Pt 2):S296-302. doi:10.1006/rtph.1996.0111
- 13Mäkinen KK, Saag M, Isotupa KP, et al. Similarity of the effects of erythritol and xylitol on some risk factors of dental caries. Caries Res. 2005;39(3):207-15. doi:10.1159/000084800
- 14Kim S, Yoo W, Park HK, Jo EJ. The First Case of Erythritol-Induced Anaphylaxis in Korea. J Korean Med Sci. 2022;37(10):e83. doi:10.3346/jkms.2022.37.e83
- 15Mazi TA, Stanhope KL. Elevated Erythritol: A Marker of Metabolic Dysregulation or Contributor to the Pathogenesis of Cardiometabolic Disease? Nutrients. 2023;15(18). doi:10.3390/nu15184011
- 16Berry AR, Ruzzene ST, Ostrander EI, et al. The non-nutritive sweetener erythritol adversely affects brain microvascular endothelial cell function. J Appl Physiol (1985). 2025;138(6):1571-1577. doi:10.1152/japplphysiol.00276.2025
- 17Wen H, Tang B, Stewart AJ, et al. Erythritol Attenuates Postprandial Blood Glucose by Inhibiting α-Glucosidase. J Agric Food Chem. 2018;66(6):1401-1407. doi:10.1021/acs.jafc.7b05033
- 18Adolphus K, Van den Abbeele P, Poppe J, et al. d-Allulose and erythritol increase butyrate production and impact the gut microbiota in healthy adults and adults with type-2 diabetes ex vivo. Benef Microbes. 2025;16(5):573-591. doi:10.1163/18762891-bja00071
- 19Arrigoni E, Brouns F, Amadò R. Human gut microbiota does not ferment erythritol. Br J Nutr. 2005;94(5):643-6. doi:10.1079/bjn20051546
- 20Boesten DM, Berger A, de Cock P, et al. Multi-targeted mechanisms underlying the endothelial protective effects of the diabetic-safe sweetener erythritol. PLoS One. 2013;8(6):e65741. doi:10.1371/journal.pone.0065741