Hydrogenated oil

What the research shows

Concerning

in studies of people

A fat made by turning liquid oil into a solid.

It makes oils solid or semi-solid, like in margarine.12

What research says

Studies in people

  • Concern

    Heart and blood sugar risk3

    In adults, hydrogenated oil and ruminant trans fats can raise heart and blood sugar risk factors, especially cholesterol.

  • Concern

    Heart and blood vessel risk4

    In people, hydrogenated oil's trans fats raise the bad-to-good cholesterol ratio, a sign of heart risk.

  • Concern

    Heart disease risk7

    Eating hydrogenated oil raises the bad cholesterol and lowers the good, which is linked to heart disease.

  • Open question

    Trans fat intake8

    Hydrogenated oil is a source of trans fats, and how much people eat varies by country and diet.

  • Concern

    Breast cancer risk9

    In women, eating more industrial trans fats was linked to a higher chance of breast cancer.

  • Concern

    Heart attack risk10

    People who ate the most hydrogenated oil fats had more heart attacks than those who ate the least.

  • Concern

    Long-term death risk11

    In people, higher levels of elaidic acid from hydrogenated oil were linked to more deaths over time.

  • Concern

    Colon cancer risk12

    In people, trans fats from partially hydrogenated fats were weakly linked to colon cancer in women, but not in men.

  • Concern

    Heart and blood vessels13

    In studies, eating trans fatty acids from margarine may raise heart disease risk more than saturated fats.

How it’s made and used

  • Dietary fat sources5

    In Slovenia, butter and meat were the main sources of trans fats, not hydrogenated oil.

  • Trans fat intake in Canada6

    Most Canadians already ate less trans fat than the recommended limit, and hydrogenated oil was not the main source for young children.

The signal at the top counts the findings in people and in animal and lab studies. A concern in studies of people outranks animal and lab studies, and “No concerns” needs at least one finding in people. When most findings in people point one way, the page leans that way (“Mostly”), and every finding is still shown. Findings whose study type is not stated are shown but not counted. This page is a reference, not medical advice. It describes what regulators and published research say. Talk to a doctor or dietitian about your own diet.

References

  1. 1hydrogenated oil: ingredient taxonomy entry. Open Food Facts.
  2. 2Hydrogenation. Wikipedia. Accessed September 26, 2026. CC BY-SA 4.0.
  3. 3Verneque BJF, Machado AM, de Abreu Silva L, Lopes ACS, Duarte CK. Ruminant and industrial trans-fatty acids consumption and cardiometabolic risk markers: A systematic review. Crit Rev Food Sci Nutr. 2022;62(8):2050-2060. doi:10.1080/10408398.2020.1836471
  4. 4Ascherio A. Trans fatty acids and blood lipids. Atheroscler Suppl. 2006;7(2):25-7. doi:10.1016/j.atherosclerosissup.2006.04.018
  5. 5Zupanič N, Hribar M, Hristov H, et al. Dietary Intake of trans Fatty Acids in the Slovenian Population. Nutrients. 2021;13(1). doi:10.3390/nu13010207
  6. 6Demonty I, Wang KC, Rondeau I, et al. Dietary intakes of trans fatty acids before the prohibition of partially hydrogenated oils in Canada. Eur J Nutr. 2024;64(1):59. doi:10.1007/s00394-024-03569-7
  7. 7Iqbal MP. Trans fatty acids - A risk factor for cardiovascular disease. Pak J Med Sci. 2014;30(1):194-7. doi:10.12669/pjms.301.4525
  8. 8Craig-Schmidt MC. World-wide consumption of trans fatty acids. Atheroscler Suppl. 2006;7(2):1-4. doi:10.1016/j.atherosclerosissup.2006.04.001
  9. 9Matta M, Huybrechts I, Biessy C, et al. Dietary intake of trans fatty acids and breast cancer risk in 9 European countries. BMC Med. 2021;19(1):81. doi:10.1186/s12916-021-01952-3
  10. 10Ascherio A, Hennekens CH, Buring JE, Master C, Stampfer MJ, Willett WC. Trans-fatty acids intake and risk of myocardial infarction. Circulation. 1994;89(1):94-101. doi:10.1161/01.cir.89.1.94
  11. 11Wang S, Tian W, Liu Y, et al. Temporal trend of circulating trans-fatty acids and risk of long-term mortality in general population. Clin Nutr. 2021;40(3):1095-1101. doi:10.1016/j.clnu.2020.07.010
  12. 12Slattery ML, Benson J, Ma KN, Schaffer D, Potter JD. Trans-fatty acids and colon cancer. Nutr Cancer. 2001;39(2):170-5. doi:10.1207/S15327914nc392_2
  13. 13Stender S, Dyerberg J, Hølmer G, Ovesen L, Sandström B. The influence of trans fatty acids on health: a report from the Danish Nutrition Council. Clin Sci (Lond). 1995;88(4):375-92. doi:10.1042/cs0880375