Hydrogenated oil
What the research shows
Concerning
in studies of people
What research says
Studies in people
-
Concern
Heart and blood sugar risk3
In adults, hydrogenated oil and ruminant trans fats can raise heart and blood sugar risk factors, especially cholesterol.
-
Concern
Heart and blood vessel risk4
In people, hydrogenated oil's trans fats raise the bad-to-good cholesterol ratio, a sign of heart risk.
-
Concern
Heart disease risk7
Eating hydrogenated oil raises the bad cholesterol and lowers the good, which is linked to heart disease.
-
Open question
Trans fat intake8
Hydrogenated oil is a source of trans fats, and how much people eat varies by country and diet.
-
Concern
Breast cancer risk9
In women, eating more industrial trans fats was linked to a higher chance of breast cancer.
-
Concern
Heart attack risk10
People who ate the most hydrogenated oil fats had more heart attacks than those who ate the least.
-
Concern
Long-term death risk11
In people, higher levels of elaidic acid from hydrogenated oil were linked to more deaths over time.
-
Concern
Colon cancer risk12
In people, trans fats from partially hydrogenated fats were weakly linked to colon cancer in women, but not in men.
-
Concern
Heart and blood vessels13
In studies, eating trans fatty acids from margarine may raise heart disease risk more than saturated fats.
How it’s made and used
-
Dietary fat sources5
In Slovenia, butter and meat were the main sources of trans fats, not hydrogenated oil.
-
Trans fat intake in Canada6
Most Canadians already ate less trans fat than the recommended limit, and hydrogenated oil was not the main source for young children.
The signal at the top counts the findings in people and in animal and lab studies. A concern in studies of people outranks animal and lab studies, and “No concerns” needs at least one finding in people. When most findings in people point one way, the page leans that way (“Mostly”), and every finding is still shown. Findings whose study type is not stated are shown but not counted. This page is a reference, not medical advice. It describes what regulators and published research say. Talk to a doctor or dietitian about your own diet.
References
- 1hydrogenated oil: ingredient taxonomy entry. Open Food Facts.
- 2Hydrogenation. Wikipedia. Accessed September 26, 2026. CC BY-SA 4.0.
- 3Verneque BJF, Machado AM, de Abreu Silva L, Lopes ACS, Duarte CK. Ruminant and industrial trans-fatty acids consumption and cardiometabolic risk markers: A systematic review. Crit Rev Food Sci Nutr. 2022;62(8):2050-2060. doi:10.1080/10408398.2020.1836471
- 4Ascherio A. Trans fatty acids and blood lipids. Atheroscler Suppl. 2006;7(2):25-7. doi:10.1016/j.atherosclerosissup.2006.04.018
- 5Zupanič N, Hribar M, Hristov H, et al. Dietary Intake of trans Fatty Acids in the Slovenian Population. Nutrients. 2021;13(1). doi:10.3390/nu13010207
- 6Demonty I, Wang KC, Rondeau I, et al. Dietary intakes of trans fatty acids before the prohibition of partially hydrogenated oils in Canada. Eur J Nutr. 2024;64(1):59. doi:10.1007/s00394-024-03569-7
- 7Iqbal MP. Trans fatty acids - A risk factor for cardiovascular disease. Pak J Med Sci. 2014;30(1):194-7. doi:10.12669/pjms.301.4525
- 8Craig-Schmidt MC. World-wide consumption of trans fatty acids. Atheroscler Suppl. 2006;7(2):1-4. doi:10.1016/j.atherosclerosissup.2006.04.001
- 9Matta M, Huybrechts I, Biessy C, et al. Dietary intake of trans fatty acids and breast cancer risk in 9 European countries. BMC Med. 2021;19(1):81. doi:10.1186/s12916-021-01952-3
- 10Ascherio A, Hennekens CH, Buring JE, Master C, Stampfer MJ, Willett WC. Trans-fatty acids intake and risk of myocardial infarction. Circulation. 1994;89(1):94-101. doi:10.1161/01.cir.89.1.94
- 11Wang S, Tian W, Liu Y, et al. Temporal trend of circulating trans-fatty acids and risk of long-term mortality in general population. Clin Nutr. 2021;40(3):1095-1101. doi:10.1016/j.clnu.2020.07.010
- 12Slattery ML, Benson J, Ma KN, Schaffer D, Potter JD. Trans-fatty acids and colon cancer. Nutr Cancer. 2001;39(2):170-5. doi:10.1207/S15327914nc392_2
- 13Stender S, Dyerberg J, Hølmer G, Ovesen L, Sandström B. The influence of trans fatty acids on health: a report from the Danish Nutrition Council. Clin Sci (Lond). 1995;88(4):375-92. doi:10.1042/cs0880375