Perilla
What the research shows
No concerns
none of the findings here link it to harm
A herb, seed and vegetable crop from the mint family.1
What research says
Studies in people
-
Open question
Asthma breathing and blood fats2
In people with asthma, perilla seed oil lowered some blood fats and improved breathing in some, but not others.
-
Benefit
Blood pressure and heart risk3
In healthy Japanese adults, perilla leaf powder lowered oxidized LDL and, in those with slightly high blood pressure, reduced morning systolic pressure.
-
Benefit
Heart artery health4
In people, drinking red perilla extract slowed the oxidation of LDL cholesterol, a step linked to hardened arteries.
Animal and lab studies only
-
Benefit
Gut health and aging8
In lab studies, perilla peptides boosted good gut bacteria, supported skin, and helped blood sugar.
-
Benefit
Weight gain and body fat9
In animal studies, purple perilla prevented weight gain and cut body fat in mice fed high-fat diets.
-
Benefit
Memory and brain health10
In animal studies, ALA from perilla oil helped prevent memory loss caused by a brain protein.
Study type not stated
-
Benefit
Heart and blood vessel health5
Perilla seed oil is rich in omega-3 fats that may help lower blood cholesterol and support heart health.
-
Benefit
Fat processing in the body6
Perilla oil may help the body handle fats, but scientists still need to find the right amount.
-
Benefit
Heart and blood fats7
Perilla seeds contain omega-3 fats, which may lower cholesterol and support heart health.
The signal at the top counts the findings in people and in animal and lab studies. A concern in studies of people outranks animal and lab studies, and “No concerns” needs at least one finding in people. When most findings in people point one way, the page leans that way (“Mostly”), and every finding is still shown. Findings whose study type is not stated are shown but not counted. This page is a reference, not medical advice. It describes what regulators and published research say. Talk to a doctor or dietitian about your own diet.
Products
The 3 most-scanned of 52 products on Open Food Facts that list perilla.
- Shiso Fumi Furikake Rice Seasoning Jfc · 10 g 0 additives
- Eden Shake Sesame & Sea Vegetable Seasoning Eden 0 additives
- Ume Plum Vinegar Eden Foods Inc. · 5 ml 0 additives
References
- 1Perilla. Wikipedia. Accessed September 30, 2026. CC BY-SA 4.0.
- 2Okamoto M, Mitsunobu F, Ashida K, et al. Effects of perilla seed oil supplementation on leukotriene generation by leucocytes in patients with asthma associated with lipometabolism. Int Arch Allergy Immunol. 2000;122(2):137-42. doi:10.1159/000024369
- 3Hashimoto M, Tanabe Y, Hossain S, et al. Intake of Alpha-Linolenic Acid-Rich Perilla frutescens Leaf Powder Decreases Home Blood Pressure and Serum Oxidized Low-Density Lipoprotein in Japanese Adults. Molecules. 2020;25(9). doi:10.3390/molecules25092099
- 4Saita E, Kishimoto Y, Tani M, et al. Antioxidant activities of Perilla frutescens against low-density lipoprotein oxidation in vitro and in human subjects. J Oleo Sci. 2012;61(3):113-20. doi:10.5650/jos.61.113
- 5Guan L, Zhu L, Zhang X, et al. Perilla Seed Oil and Protein: Composition, Health Benefits, and Potential Applications in Functional Foods. Molecules. 2024;29(22). doi:10.3390/molecules29225258
- 6Xia J, Wang Y, Li X, et al. The mechanism of perilla oil in regulating lipid metabolism. Food Chem. 2025;476:143318. doi:10.1016/j.foodchem.2025.143318
- 7Kaur S, Seem K, Ali A, et al. A comprehensive review on nutritional, nutraceutical, and industrial perspectives of perilla (Perilla frutscens L.) seeds - An orphan oilseed crop. Heliyon. 2024;10(12):e33281. doi:10.1016/j.heliyon.2024.e33281
- 8Hu Y, Luo H, Netala VR, Li H, Zhang Z, Hou T. Comprehensive Review of Biological Functions and Therapeutic Potential of Perilla Seed Meal Proteins and Peptides. Foods. 2024;14(1). doi:10.3390/foods14010047
- 9Thomas SS, Kim M, Lee SJ, Cha YS. Antiobesity Effects of Purple Perilla (Perilla frutescens var. acuta) on Adipocyte Differentiation and Mice Fed a High-fat Diet. J Food Sci. 2018;83(9):2384-2393. doi:10.1111/1750-3841.14288
- 10Lee AY, Lee MH, Lee S, Cho EJ. Alpha-Linolenic Acid from Perilla frutescens var. japonica Oil Protects Aβ-Induced Cognitive Impairment through Regulation of APP Processing and Aβ Degradation. J Agric Food Chem. 2017;65(49):10719-10729. doi:10.1021/acs.jafc.7b03941