Perilla

What the research shows

No concerns

none of the findings here link it to harm

A herb, seed and vegetable crop from the mint family.1

What research says

Studies in people

  • Open question

    Asthma breathing and blood fats2

    In people with asthma, perilla seed oil lowered some blood fats and improved breathing in some, but not others.

  • Benefit

    Blood pressure and heart risk3

    In healthy Japanese adults, perilla leaf powder lowered oxidized LDL and, in those with slightly high blood pressure, reduced morning systolic pressure.

  • Benefit

    Heart artery health4

    In people, drinking red perilla extract slowed the oxidation of LDL cholesterol, a step linked to hardened arteries.

Animal and lab studies only

  • Benefit

    Gut health and aging8

    In lab studies, perilla peptides boosted good gut bacteria, supported skin, and helped blood sugar.

  • Benefit

    Weight gain and body fat9

    In animal studies, purple perilla prevented weight gain and cut body fat in mice fed high-fat diets.

  • Benefit

    Memory and brain health10

    In animal studies, ALA from perilla oil helped prevent memory loss caused by a brain protein.

Study type not stated

  • Benefit

    Heart and blood vessel health5

    Perilla seed oil is rich in omega-3 fats that may help lower blood cholesterol and support heart health.

  • Benefit

    Fat processing in the body6

    Perilla oil may help the body handle fats, but scientists still need to find the right amount.

  • Benefit

    Heart and blood fats7

    Perilla seeds contain omega-3 fats, which may lower cholesterol and support heart health.

The signal at the top counts the findings in people and in animal and lab studies. A concern in studies of people outranks animal and lab studies, and “No concerns” needs at least one finding in people. When most findings in people point one way, the page leans that way (“Mostly”), and every finding is still shown. Findings whose study type is not stated are shown but not counted. This page is a reference, not medical advice. It describes what regulators and published research say. Talk to a doctor or dietitian about your own diet.

Products

The 3 most-scanned of 52 products on Open Food Facts that list perilla.

  • Shiso Fumi Furikake Rice Seasoning Jfc · 10 g 0 additives
  • Eden Shake Sesame & Sea Vegetable Seasoning Eden 0 additives
  • Ume Plum Vinegar Eden Foods Inc. · 5 ml 0 additives

References

  1. 1Perilla. Wikipedia. Accessed September 30, 2026. CC BY-SA 4.0.
  2. 2Okamoto M, Mitsunobu F, Ashida K, et al. Effects of perilla seed oil supplementation on leukotriene generation by leucocytes in patients with asthma associated with lipometabolism. Int Arch Allergy Immunol. 2000;122(2):137-42. doi:10.1159/000024369
  3. 3Hashimoto M, Tanabe Y, Hossain S, et al. Intake of Alpha-Linolenic Acid-Rich Perilla frutescens Leaf Powder Decreases Home Blood Pressure and Serum Oxidized Low-Density Lipoprotein in Japanese Adults. Molecules. 2020;25(9). doi:10.3390/molecules25092099
  4. 4Saita E, Kishimoto Y, Tani M, et al. Antioxidant activities of Perilla frutescens against low-density lipoprotein oxidation in vitro and in human subjects. J Oleo Sci. 2012;61(3):113-20. doi:10.5650/jos.61.113
  5. 5Guan L, Zhu L, Zhang X, et al. Perilla Seed Oil and Protein: Composition, Health Benefits, and Potential Applications in Functional Foods. Molecules. 2024;29(22). doi:10.3390/molecules29225258
  6. 6Xia J, Wang Y, Li X, et al. The mechanism of perilla oil in regulating lipid metabolism. Food Chem. 2025;476:143318. doi:10.1016/j.foodchem.2025.143318
  7. 7Kaur S, Seem K, Ali A, et al. A comprehensive review on nutritional, nutraceutical, and industrial perspectives of perilla (Perilla frutscens L.) seeds - An orphan oilseed crop. Heliyon. 2024;10(12):e33281. doi:10.1016/j.heliyon.2024.e33281
  8. 8Hu Y, Luo H, Netala VR, Li H, Zhang Z, Hou T. Comprehensive Review of Biological Functions and Therapeutic Potential of Perilla Seed Meal Proteins and Peptides. Foods. 2024;14(1). doi:10.3390/foods14010047
  9. 9Thomas SS, Kim M, Lee SJ, Cha YS. Antiobesity Effects of Purple Perilla (Perilla frutescens var. acuta) on Adipocyte Differentiation and Mice Fed a High-fat Diet. J Food Sci. 2018;83(9):2384-2393. doi:10.1111/1750-3841.14288
  10. 10Lee AY, Lee MH, Lee S, Cho EJ. Alpha-Linolenic Acid from Perilla frutescens var. japonica Oil Protects Aβ-Induced Cognitive Impairment through Regulation of APP Processing and Aβ Degradation. J Agric Food Chem. 2017;65(49):10719-10729. doi:10.1021/acs.jafc.7b03941