Pomegranate
What the research shows
No concerns
none of the findings here link it to harm
The fruit of a shrub that grows 1.5–5 metres tall.
The fruit and its juice are used in baking, cooking, juice blends, garnishes, nonalcoholic drinks, and cocktails.1
What research says
Studies in people
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Benefit
Joint pain in arthritis2
In people with arthritis, pomegranate juice or extract seemed to ease joint pain and swelling, but the evidence is weak.
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Benefit
Heart and blood sugar health3
In people, pomegranate supplements slightly lowered blood pressure, blood sugar and cholesterol, though scientists say more research is needed.
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Benefit
Blood inflammation marker4
Pomegranate juice lowered a blood marker of inflammation in people, but scientists say more studies are needed.
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Benefit
Gut bacteria health5
Pomegranate feeds good gut bacteria, but how much urolithin your body makes from it varies from person to person.
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Benefit
Gut bacteria and colon cancer7
In people newly diagnosed with colon cancer, eating pomegranate lowered a blood marker of gut bacteria leaking into the body.
Animal and lab studies only
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Benefit
Metabolic syndrome risk factors12
In animal studies, pomegranate and its extracts seemed to help with blood sugar, cholesterol, blood pressure and weight.
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Benefit
Heart disease risk13
In lab studies, pomegranate's punicalagin blocked gut bacteria from making a compound linked to heart disease.
Study type not stated
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Benefit
Gut bacteria and nutrient absorption8
Pomegranate's benefits may depend on gut bacteria turning its compounds into usable forms.
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Benefit
Heart and gut health9
Pomegranate has plant compounds, and studies suggest it may help the heart and digestion.
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Benefit
Brain health and memory10
Pomegranate may help brain diseases like Alzheimer's, but scientists do not yet know whether it truly works in people.
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Open question
Compound interactions in humans11
Scientists do not yet know how the many compounds in pomegranate work together in people.
Single cases of misuse or overdose
One person or one incident, such as an accidental overdose or a mistake in a kitchen or factory. They are real, but a single case does not show what happens at normal amounts, so the signal does not count them.
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Allergic reaction in a child6
A 7-year-old with asthma had a breathing reaction right after eating pomegranate seeds.
The signal at the top counts the findings in people and in animal and lab studies. A concern in studies of people outranks animal and lab studies, and “No concerns” needs at least one finding in people. When most findings in people point one way, the page leans that way (“Mostly”), and every finding is still shown. Findings whose study type is not stated are shown but not counted. This page is a reference, not medical advice. It describes what regulators and published research say. Talk to a doctor or dietitian about your own diet.
Products
The 6 most-scanned of 1,470 products on Open Food Facts that list pomegranate.
- Beyond Burger Beyond Meat · 226 g 3 additives
- organic supergreens fruits & vegetables zena greens 4 additives
- Beyond Burger Beyond Meat · 226 g (2x113 g) 3 additives
- Super Nutty Wholefood Marks & Spencers · 230 g 0 additives
- Nutty Super Wholefood M&S Food · 285 g 0 additives
- Protein Pancake & Waffle Mix Flourish · 1 kg 1 additive
References
- 1Pomegranate. Wikipedia. Accessed September 29, 2026. CC BY-SA 4.0.
- 2de Carvalho JF, Hautz E. Pomegranate (Punica granatum) as an adjunctive therapy in rheumatic diseases: A systematic review. Clin Nutr ESPEN. 2026;72:102809. doi:10.1016/j.clnesp.2025.11.017
- 3Mohammadi S, Heshmati J, Baziar N, et al. Impacts of supplementation with pomegranate on cardiometabolic risk factors: A systematic review and dose-response meta-analysis. Nutr Metab Cardiovasc Dis. 2025;35(10):104154. doi:10.1016/j.numecd.2025.104154
- 4Jazinaki MS, Rashidmayvan M, Pahlavani N. The effect of pomegranate juice supplementation on C-reactive protein levels: GRADE-assessed systematic review and dose-response updated meta-analysis of data from randomized controlled trials. Phytother Res. 2024;38(6):2818-2831. doi:10.1002/ptr.8188
- 5Yin Y, Martínez R, Zhang W, Estévez M. Crosstalk between dietary pomegranate and gut microbiota: evidence of health benefits. Crit Rev Food Sci Nutr. 2024;64(27):10009-10035. doi:10.1080/10408398.2023.2219763
- 6Gaig P, Botey J, Gutiérrez V, Pena M, Eseverri JL, Marín A. Allergy to pomegranate (Punica granatum). J Investig Allergol Clin Immunol. 1992;2(4):216-8.
- 7González-Sarrías A , Núñez-Sánchez MA , Ávila-Gálvez MA , et al. Consumption of pomegranate decreases plasma lipopolysaccharide-binding protein levels, a marker of metabolic endotoxemia, in patients with newly diagnosed colorectal cancer: a randomized controlled clinical trial. Food Funct. 2018;9(5):2617-2622. doi:10.1039/c8fo00264a
- 8Kobylińska Z, Bochno A, Och E, et al. Phytochemical Diversity of Punica granatum L. and Its Multi-Target Biological Functions. Nutrients. 2026;18(8). doi:10.3390/nu18081306
- 9Zhou Z, Ma C, Hao P, Peng L, Zhang SY, Zhao Q. Phenolic Components and Biological Activity of Pomegranate. Chem Biodivers. 2025;22(3):e202402301. doi:10.1002/cbdv.202402301
- 10Mehdi A, Lamiae B, Samira B, et al. Pomegranate (Punica granatum L.) Attenuates Neuroinflammation Involved in Neurodegenerative Diseases. Foods. 2022;11(17). doi:10.3390/foods11172570
- 11Wu S, Tian L. Diverse Phytochemicals and Bioactivities in the Ancient Fruit and Modern Functional Food Pomegranate (Punica granatum). Molecules. 2017;22(10). doi:10.3390/molecules22101606
- 12Laurindo LF, Rodrigues VD, Minniti G, et al. Pomegranate (Punica granatum L.) phytochemicals target the components of metabolic syndrome. J Nutr Biochem. 2024;131:109670. doi:10.1016/j.jnutbio.2024.109670
- 13Haarhuis JE, Gamal El-Din MI, Lamprinaki D, Kroon PA. Punicalagin is the key pomegranate polyphenol inhibiting gut microbial trimethylamine (TMA) production from L-carnitine in an in vitro human colon model. Food Funct. 2026;17(4):1827-1840. doi:10.1039/d5fo04781a