Systematic review · Journal of public health (Oxford, England) · 2016

Bifidobacterium lactis and the science behind advertising claims in people

What it found

Only four trials in people backed up the claim that Bifidobacterium lactis speeds up gut transit.

None of the trials supported the immune defence claims made for Lactobacillus casei.

What they found

Studies in people

Gut transit time

Four trials in people found that Bifidobacterium lactis shortened the time food takes to move through the gut. These were the only studies rated as strong evidence by the authors.

Immune system markers

Trials in people looking at Lactobacillus casei measured things like immune cells and antibodies in blood or saliva. The authors say none showed real clinical benefits matching the advertising claims.

Stool frequency

Several trials in people found no difference in how often participants went to the toilet when taking Bifidobacterium lactis compared to a control product.

Other findings

Company website studies

The company website listed 47 studies, but only 12 met the strict criteria the authors set. Of the 35 website studies left out, most tested sick people or measured unrelated effects.

Funding sources

In 7 of the 16 included trials, the company declared it paid for the research. In several others, the company supplied the product or an author was linked to the firm.

What the authors conclude

  • They conclude there is not enough scientific proof to back the health claims advertised for these products, especially for Lactobacillus casei.
  • They advise policymakers to tighten rules so companies cannot use weak evidence in food advertising.
  • They suggest doctors should be aware of how much trust shoppers place in these marketing messages.

How it was done

Companies advertise fermented milk drinks as boosting immunity or improving digestion. The authors wanted to check if the science actually supports those messages, and whether company websites show the full picture.

They searched medical databases for human trials testing these two specific bacteria in healthy people. They found 16 randomised controlled trials matching their criteria and compared them with 47 studies listed on the company website.

What it can’t tell you

  • These trials looked only at healthy people, so they cannot show what happens in someone who is ill.
  • A trial can show cause and effect for what it measured, but many of these studies relied on people reporting their own symptoms, which can be influenced by expectations.

The paper

Title
Does the scientific evidence support the advertising claims made for products containing Lactobacillus casei and Bifidobacterium lactis? A systematic review
Type
Systematic review
Evidence
Studies in people
Summarised from
Full text
Cite
Meléndez-Illanes L, González-Díaz C, Chilet-Rosell E, Álvarez-Dardet C (2016). Does the scientific evidence support the advertising claims made for products containing Lactobacillus casei and Bifidobacterium lactis? A systematic review. Journal of public health (Oxford, England). doi:10.1093/pubmed/fdv151Free full textPubMed 26515088DOI

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