Review · Allergy · 2016Abstract only

Sesame and other edible seeds linked to allergic reactions

What it found

Allergic reactions to sesame and five other common seeds can be severe, with sesame allergy estimated at 0.1-0.2% of people.

Pinpointing the exact seed causing a reaction is often difficult.

What they found

Studies in people

How common sesame allergy is

Sesame allergy was reported more often than allergies to the other five seeds. The estimated rate in people is 0.1-0.2%.

Severity of reactions

Allergic reactions to these seeds can be severe. Reactions may happen through different routes of exposure, including their oils.

Diagnosing seed allergies

Routine allergy tests have limited reliability for these seeds. Doctors need a careful patient history and specific challenge tests to confirm an allergy.

Current treatment options

Management relies on avoiding the seed in food and using symptom-relief medicines. These medicines may include epinephrine auto-injectors.

Studies in people and animals

Cross-reactions between seeds

People allergic to one seed may also react to other seeds or certain foods. The authors identified the main proteins responsible for these reactions.

What the authors conclude

  • They note that no well-designed studies on immunotherapy for seed allergies exist yet.
  • They hope that safe and effective treatment protocols will be developed soon.

How it was done

Seeds are being added to more foods, raising the chance of severe allergic reactions. Identifying which seed caused a problem is often hard or not attempted.

The authors searched English-language medical literature from January 1930 to March 2016 for reports on allergies to six edible seeds. They looked at sesame, sunflower, poppy, pumpkin, flaxseed and mustard seed. Most published work consisted of single case reports rather than large studies.

What it can’t tell you

  • We summarised it from the abstract only.
  • Most evidence comes from individual case reports rather than large studies, so true rates may differ.
  • This summary cannot show how often mild versus severe reactions occur across all people who eat these seeds.

The paper

Title
Hypersensitivities to sesame and other common edible seeds
Type
ReviewThe authors read earlier studies and describe what they found. It isn’t a new study.
Evidence
Studies in people · animals · lab
Summarised from
Abstract only
Cite
Patel A, Bahna SL (2016). Hypersensitivities to sesame and other common edible seeds. Allergy. doi:10.1111/all.12962PubMed 27332789DOI

Summary written 30 Sep 2026. Check it against the paper before it changes what you eat. How we summarise papers · Report an error