Randomised trial · Journal of the International Society of Sports Nutrition · 2017

Cranberry extract, iron and inflammation in rowers

What it found

In 16 rowers, cranberry extract raised antioxidant capacity in the blood but did not change most markers of inflammation or iron.

The authors say it strengthened antioxidant potential after hard exercise.

What they found

Studies in people

Antioxidant capacity

After 6 weeks, the cranberry group had higher total antioxidant capacity at rest, after exercise and after recovery than the placebo group.

Inflammation markers

Cranberry extract did not significantly change levels of IL-6 or TNF-alpha. Exercise raised IL-6 in both groups at both tests.

Hepcidin and myoglobin

After exercise, the placebo group had higher hepcidin and myoglobin, but the cranberry group did not. The authors say cranberry did not directly affect these markers.

Iron and binding capacity

Serum iron, total iron-binding capacity and unbound iron-binding capacity rose after exercise in both groups at the second test. Cranberry did not significantly change these.

Ferritin and transferrin receptor

Neither cranberry nor exercise significantly changed ferritin or soluble transferrin receptor levels.

What the authors conclude

“Supplementation with cranberry extract contributed to a significant strengthening of antioxidant potential in individuals exposed to strenuous physical exercise.”
Skarpańska-Stejnborn A, Basta P, Trzeciak J, Michalska A, Kafkas ME, Woitas-Ślubowska D, 2017

Also in their conclusions

  • They conclude that cranberry extract strengthened antioxidant potential in people doing strenuous exercise.
  • They state that supplementation did not exert direct effects on inflammatory markers and indices of iron metabolism (TNF-alpha, hepcidin and myoglobin).
  • They call for more research on how cranberry components, especially anthocyanins, affect iron metabolism, and for guidelines on cranberry supplement use.

How it was done

Hard training can cause inflammation and disturb iron handling in the body. The authors wanted to see whether cranberry, which contains antioxidant and iron-binding compounds, could help.

They studied 16 male Polish national rowers during a 6-week training camp. Nine took 1200 mg of cranberry extract daily and seven took a placebo, and all did 2000-m rowing tests at the start and end.

What it can’t tell you

  • This was a small study of 16 male rowers, so the results may not apply to other people or to women.
  • The study lasted 6 weeks, so it cannot show what happens over longer periods.

The paper

Title
Effects of cranberry ( Vaccinum macrocarpon ) supplementation on iron status and inflammatory markers in rowers
Type
Randomised controlled trial
Evidence
Studies in people
Summarised from
Full text
Cite
Skarpańska-Stejnborn A, Basta P, Trzeciak J, Michalska A, Kafkas ME, Woitas-Ślubowska D (2017). Effects of cranberry ( Vaccinum macrocarpon ) supplementation on iron status and inflammatory markers in rowers. Journal of the International Society of Sports Nutrition. doi:10.1186/s12970-017-0165-zFree full textPubMed 28261001DOI

Summary written 26 Sep 2026. Check it against the paper before it changes what you eat. How we summarise papers · Report an error