Resistant dextrin, satiety and blood sugar in UK adults
What it found
In 36 healthy UK adults, 28 days of resistant dextrin changed some satiety scores and lowered the blood sugar rise after a mid-morning drink, compared with a maltodextrin control.
Body weight, body fat and waist size did not change.
What they found
Studies in people
Fasting satiety
Fasting satiety scores were higher with resistant dextrin than with the control at day 14 and day 28, but not at day 1. Across the whole group and in the normal weight group, fasting satiety was higher at day 28 than at day 1 with resistant dextrin.
Satiety after meals
After the mid-morning drink, satiety was higher with resistant dextrin at day 28 in the normal weight group. After both the lunch and evening meals, satiety was lower with resistant dextrin than with the control at day 28.
Blood sugar response
The blood sugar rise in the 30 minutes after the mid-morning drink was lower with resistant dextrin than with the control at day 28. With resistant dextrin, this response was also lower at days 14 and 28 than at day 1.
Blood pressure
In the normal weight group only, systolic blood pressure was lower at day 28 (mean 112 mmHg) than at day 1 (mean 120 mmHg) and day 14 (mean 118 mmHg) with resistant dextrin. No differences were found in the overweight group.
Body measurements
Body weight, body fat, waist and hip circumference, and diastolic blood pressure were not changed by either resistant dextrin or the control.
Energy intake
On day 1, the amount eaten at lunch was higher after the resistant dextrin mid-morning drink than after the control (mean difference 88 kcal). This was seen in the overweight group (mean difference 170 kcal) but not the normal weight group.
What the authors conclude
“In conclusion, this study provides evidence that chronic consumption of RD reduces postprandial glycaemia and influences fasted satiety in healthy adults living in the UK.”
Also in their conclusions
- They conclude that chronic consumption of resistant dextrin reduces postprandial glycaemia and influences fasted satiety in healthy adults living in the UK.
- They say that intervention studies of a greater duration are needed to determine whether resistant dextrin consumption can help regulate body weight and influence metabolic health.
- They note that the observed potential anti-hypertensive properties of resistant dextrin are of interest but require further investigation.
How it was done
Resistant dextrin had been shown to alter satiety, blood sugar and body weight in overweight Chinese men, but there was little data in other groups. The authors wanted to test its effects in normal weight and overweight adults in the United Kingdom.
36 adults (20 normal weight, 16 overweight) completed a randomised, double-blind, cross-over trial. They drank either 14 g per day of resistant dextrin (NUTRIOSE FB06) or an energy-matched maltodextrin control in mid-morning and mid-afternoon drinks for 28 days, then switched to the other drink after a 28-day break. On days 1, 14 and 28 of each period, they spent 10 hours in the clinic where satiety, blood sugar, gut hormones and blood pressure were measured around provided meals.
What it can’t tell you
- The study lasted only 28 days, so it cannot show what happens over longer periods.
- It cannot show whether resistant dextrin helps control body weight, because no weight changes were seen in this time.
- The findings in normal weight adults may not apply to overweight adults, who responded differently in this study.
Who paid
- Conflicts
- The study was funded by Roquette Ltd. who produce the resistant dextrin NUTRIOSE®. The contributing authors from Roquette helped define the study hypothesis, these authors were not involved in the study execution, analysis, or data interpretation. The academic team has no vested interest in the study outcome and was given full control over the publication of study data. All study data can be made available on request.
- Authors work at
- The University of Reading, UK; Northumbria University, UK
The paper
- Title
- Impact of dietary supplementation with resistant dextrin (NUTRIOSE ® ) on satiety, glycaemia, and related endpoints, in healthy adults
- Type
- Randomised controlled trial
- Evidence
- Studies in people
- Summarised from
- Full text
- Cite
- Hobden MR, Commane DM, Guérin-Deremaux L, et al (2021). Impact of dietary supplementation with resistant dextrin (NUTRIOSE ® ) on satiety, glycaemia, and related endpoints, in healthy adults. European journal of nutrition. doi:10.1007/s00394-021-02618-9Free full textPubMed 34170392DOI
Summary written 26 Sep 2026. Check it against the paper before it changes what you eat. How we summarise papers · Report an error